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Showing papers by "University of Bergen published in 1969"


Journal ArticleDOI
TL;DR: Evidence of exchange of mineral and organic components across the tooth-saliva interface became morphologically detectable within a few weeks after thorough planing of cementum and root dentin.
Abstract: Microradiographic and electron microscopic studies showed that cementum exposed to the oral environment can calcify beyond the normal level. Evidence of exchange of mineral and organic components across the tooth-saliva interface became morphologically detectable within a few weeks after thorough planing of cementum and root dentin.

94 citations


Journal ArticleDOI
TL;DR: When the hormone-treated seedlings were illuminated, their roots reformed starch after 20 to 24 hours; simultaneously the geotropic responsiveness was restored and the results are interpreted in support of the statolith theory.
Abstract: Roots of garden cress (Lepidium sativum L.) seedlings were made starch-free by treatment with gibberellic acid and kinetic for 29 hours at 35°C in the dark. After 3 hours of temperature adaptation at 21°C the starch-depleted roots were unable to respond to gravity, but elongated 0.48 mm por hour. Under the same conditions control roots pretreated in plain water at 21 and at 35°C elongated 0.64 and 0.33 mm per hour, respcetively (at 21°C). When the hormone-treated seedlings were illuminated, their roots reformed starch after 20 to 24 hours; simultaneously the geotropic responsiveness was restored. The results are interpreted in support of the statolith theory.

90 citations


Journal ArticleDOI
05 Apr 1969-Nature
TL;DR: Examination of the internal skeleton of amphioxus supports the view of Ebner and Joseph2, who proposed a muscular nature of the notochord.
Abstract: As is evident from every textbook of zoology, the internal skeleton or notochord of amphioxus (Branchiostoma lanceolatum) has been considered as a passive supporting organ by all but a very few investigators. Our examination, using modern techniques, however, supports the view of Ebner1 and Joseph2, who proposed a muscular nature of the notochord (Fig. 1).

56 citations


Journal ArticleDOI
Poul Larsen1
TL;DR: In this paper, the authors found that pre-inversion of the roots did suppress the curvatures produced by stimulation at angles larger than 90° when measured after 10 to 30 min of klinostat rotation.
Abstract: Roots which are turned from their normal direction to directions at various angles with the plumb line develop the largest geotropic curvatures during a subsequent klinostat rotation period when the stimulation angle is well above the horizontal. In experiments with roots of Lepidium sativum L., the optimum is located at 120 to 140° when the stimulation time is between 2 and 15 min. If this fact is to be explained by the movements of amyloplasts in the root cap cells, one would expect roots which bad been kept inverted before the stimulation (so that the moveable amyloplasts are accumulated in the opposite end of the cells) to show an optimum angle well below 90°. — Pre-inversion of the roots did suppress the curvatures produced by stimulation at angles larger than 90° when measured after 10 to 30 min of klinostat rotation. This suppression may be taken as a support for the starch statolith hypothesis, since the amyloplasts in pre-inverted roots placed at angles exceeding 90° have a restricted opportunity to slide along the cell walls compared to non-inverted roots placed at the same angles. In pre-inverted roots measured after a period of klinostat rotation, however, no optimum was found at angles below 90°. When the stimulation time was 3.75 min, the response curves were nearly symmetrical about 90°. Stimulation for 15 min, on the other hand, resulted in curvatures which were much larger (although suppressed in comparison with non-inverted roots) when the stimulation angle was 165° than when it was 15°. During the 15 min stimulation period itself, however, pre-inverted roots curved 0.3° when stimulated at 15, but only 3.4° at 165°. This small difference was very highly significant and is in agreement with the starch statolith hypothesis insofar as the amyloplasts in pre-inverted roots placed at 15° have the greatest opportunity to slide along the cell walls. The lack of further development (and the actual decrease) of their curvatures during the subsequent klinostat rotation must then be due to other, depressing, factors, summarily designated as tonic. At angles above 90°, the tonic factors are either absent or even enhancing. Tbe tonic effects cannot be explained by amyloplast movements.

52 citations


Journal Article
TL;DR: Evidence is presented that a protein having immunological properties identical with those of a chromogranin purified from chromaffin granules (obtained from bovine adrenal medullae) is present in granules isolated from bOVine splenic nerve.
Abstract: Evidence is presented that a protein having immunological properties identical with those of a chromogranin purified from chromaffin granules (obtained from bovine adrenal medullae) is present in granules isolated from bovine splenic nerve. The possibility that chromogranin plays a role in noradrenaline storage in splenic nerve granules as well as in chromaffin granules is discussed.

49 citations


Journal ArticleDOI
Tor Hofstad1
TL;DR: The isolated LPS was antigenic in rabbits, giving rise to low- and high-molecular-weight antibodies, and cross-reactivity experiments revealed the presence in LPS of both type-specific and group-reactive antigenic determinants.
Abstract: Lipopolysaccharide (LPS) extracted with phenol-water from four oral strains of Bacteroides melaninogenicus was found to be serologically active in precipitation and complement fixation tests and sensitized sheep erythrocytes to agglutination. Except for the capacity to inhibit indirect hemagglutination, the serological activity was destroyed by oxidation with periodate. The isolated LPS was antigenic in rabbits, giving rise to low- and high-molecular-weight antibodies. Cross-reactivity experiments revealed the presence in LPS of both type-specific and group-reactive antigenic determinants.

49 citations


Journal ArticleDOI
15 Oct 1969-Sarsia
TL;DR: Samples of Corallina were obtained at various times of the year from the intertidal and subtidal zones at the two more exposed localities and some 70 species and several higher groups were recorded and in most cases counted.
Abstract: Three localities south of Bergen, one sheltered, one semi-exposed, and one very exposed, were chosen. Samples of Corallina were obtained at various times of the year from the intertidal and subtidal zones at the two more exposed localities. At the sheltered locality samples were taken from just below the intertidal zone only. Some 70 species and several higher groups were recorded and in most cases counted. The size of the animals found living on the plants is considered in relation to the form of growth of Corallina and the faunal composition in relation to the degree of exposure.

43 citations




Journal ArticleDOI
TL;DR: Uptake is slower than uptake of amino acids, and may involve a different mechanism, and the types of molecules absorbed, together with the significance these may have in the overall metabolism, are considered.
Abstract: 1. The oxygen consumption of S. ekmani at 5° C is 0.06 µl./mg./hr. 2. Phenylalanine and glycine are concentrated by S. ekmani . The concentration factor reaches a maximum after 30 min. in animals removed from their tubes. In animals inside their tubes, the rate of uptake is limited by the rate of diffusion through the walls of the tube. The phenylalanine does not move appreciably into the alcohol-insoluble extract of the animals over a period of 1 hr. 3. Protein is taken up by S. ekmani when animals are removed from their tubes. Uptake is slower than uptake of amino acids, and may involve a different mechanism. 4. Autoradiography using S. mergophorum shows that phenylalanine is not adsorbed on the cuticle. It is found especially in secretory cells, within which it is localized over rough endoplasmic reticulum, Golgi regions and secretion spherules. 5. The site and mechanism of uptake of organic molecules are discussed; and the types of molecules absorbed, together with the significance these may have in the overall metabolism, are considered.

36 citations


Journal ArticleDOI
TL;DR: In rats with ventromedial hypothalamic lesions, obesity was observed only when Prussian blue positive substance was deposited in the lesion, and implantation of iron was not effective in producing obesity.


Journal ArticleDOI
TL;DR: In this article, a palaeomagnetic study of samples from 8 localities along the Upper Carboniferous is presented, where alternating field and thermal demagnetization studies reveal secondary components of both low and high stability.

Journal ArticleDOI
TL;DR: Methods for conjugate hydrolysis and ether extraction of simple phenols in urine have been investigated and recoveries of some dihydroxybenzenes were considerably reduced and these losses were shown to occur during the removal of phenolic acids.

Journal ArticleDOI
TL;DR: The most striking trend in the total cases of endometrial carcinoma in Norway from 1957 through 1960 is the increasing mortality with increasing age, even if corrected for natural mortality.

Journal ArticleDOI
TL;DR: The enzymatic activity of the DTNB-treated enzyme could be fully restored by addition of reducing agents such as 2-mercaptoethanol and the reconstituted enzyme possessed the same sedimentation properties as the native holoenzyme.

Journal ArticleDOI
15 Oct 1969-Sarsia
TL;DR: This species probably causes considerable loss of plants due to weekening of the holdfast in one case and grazing of the frond and stipe in the second in the Isle of Man.
Abstract: The behaviour of the gastropod, Patina pellucida, on Laminaria hyperborea has been investigated in the Isle of Man and near Bergen, western Norway. The animals first settle on the frond. In Britain they later migrate down the stipe and enter the holdfast where they create large cavities while in Norway they remain on the frond and the uppermost part of the stipe. This species probably causes considerable loss of plants due to weekening of the holdfast in one case and grazing of the frond and stipe in the second. The degree of infestation in different plant age-groups has been investigated in the Isle of Man.

Journal ArticleDOI
TL;DR: Investigation of autotransplantation of teeth in order to achieve a greater certainty of indication and prognosis for this reconstructive form of surgery found that a difference in the percentage of successful cases in various age-groups could not be shown within the above age limits.

Journal ArticleDOI
TL;DR: During interphase, when the nuclei of both micro- and mesomere (macromere) had intact nuclear membranes, there also was a break down of the cell walls and a syncytium was formed by the “host cell” and the implanted micromere (see Fig 6).
Abstract: The cleavage pattern of the young sea urchin embryo was studied by means of light and electron microscopy.

Journal ArticleDOI
TL;DR: In this article, a standard method was developed using 1% w/w Carbowax 20 M on Chromosorb W (AW-DMCS) and temperature programming (130° → 185°C at 3°C/min).

Journal ArticleDOI
TL;DR: High frequency electrical stimulation of eight points in the head of the caudate nucleus in six unanesthetized, freely moving cats yielded an orientation response from all points, indistinguishable from the orienting response elicited by novel, acoustic stimulation and by Electrical stimulation of the amygdala, parts of cortex, and the mesencephalic reticular formation.

Journal ArticleDOI
01 Sep 1969-Planta
TL;DR: Ultrathin sections through the median plane of norm al, 48-hrs-old seedling roots of cress, showed the presence of accumulations of a finely fibrillar material and the rod-shaped structure and random orientation of these inclusions were clearly seen in 3-dimensional reconstructions of serial ultrathinsections.
Abstract: Ultrathin sections through the median plane of norm al, 48-hrs-old seedling roots of cress, showed the presence of accumulations of a finely fibrillar material. These inclusions were confined to the cisternae of the granular endoplasmic reticulum of surface cell layers of the root tip and the root-hair zone. The rod-shaped structure and random orientation of these inclusions were clearly seen in 3-dimensional reconstructions of serial ultrathin sections.

Journal ArticleDOI
TL;DR: Two families are reported in which Down's syndrome was transmitted through phenotypi‐cally normal mosaic mothers, and in the first family the mother had normal/G‐trisomy mosaic, and on two successive pregnancies at the age of 22 and 24 years she gave birth to two sibs with regular G2i‐Trisomy and Down's Syndrome.
Abstract: Summary Two families are reported in which Down's syndrome was transmitted through phenotypi-cally normal mosaic mothers. In the first family the mother had normal/G-trisomy mosaic, and on two successive pregnancies at the age of 22 and 24 years she gave birth to two sibs with regular G2i-trisomy and Down's syndrome. In the other family the mother had a mosaic of normal and balanced D/G21 translocation cells, and at the age of 32 years she gave birth to a child with D/G2t translocation trisomy and Down's syndrome. Mosaic mothers carry a considerable risk of having children with Down's syndrome. Exact prediction of the risk cannot be given since the extent of gonadal involvement in the mosaicism is unknown.

Journal ArticleDOI
TL;DR: Circulatory and respiratory responses to increasing exercise loads revealed a hyperkinetic circulation which was normalized after glucose medication and lack of hyperventilation in strenuous exercise and low functional dimensions in the cardiovascular system.
Abstract: The maximal oxygen uptake of a patient suffering from McArdle's disease was 1.82 1/min, or about 50% of normal value. Neither exhaustive dynamic nor static work resulted in lactate formation. The maximal oxygen debt was 1.87 1, which is 15–20% of normal value. Circulatory and respiratory responses to increasing exercise loads revealed a hyperkinetic circulation which was normalized after glucose medication. There were lack of hyperventilation in strenuous exercise and low functional dimensions in the cardiovascular system.

Journal ArticleDOI
TL;DR: In this paper, a detailed level scheme for 35Cl has been determined up to an excitation energy of 5.8 MeV revealing several previously unobserved states, including Coulomb displacement and symmetry energies.

Journal ArticleDOI
TL;DR: The high-potential iron protein (HiPIP) of Chromatium was distinguished from various ferredoxins by its characteristic mode of iron binding, and it was concluded that the unique ellipticity band centered around 230 nm was attributable to iron-SH bondings.

Journal ArticleDOI
TL;DR: N-ethyl maleimide a known cellular radiosensitizer was studied from a radiation chemical viewpoint and was found to react rapidly with water free radicals, which may explain in part the mode of action of NEM as a radiosENSitizer at the cellular level.
Abstract: SummaryN-ethyl maleimide (NEM) a known cellular radiosensitizer was studied from a radiation chemical viewpoint. It was found to react rapidly with water free radicals. The NEM-OH radical adduct can react further with another NEM molecule in the absence of oxygen. NEM also reacts with radicals produced by the reactions of OH free radicals and hydrated electrons with nucleic acid components. These reactions occur in the absence of oxygen by both electron transfer and bond formation. NEM is able to compete with oxygen for free radicals produced by reaction of OH + thymine. These oxygen-like reactions of NEM may explain in part the mode of action of NEM as a radiosensitizer at the cellular level.

Journal ArticleDOI
TL;DR: It is generally concluded that the investigated characteristics of Cystophora blood differ from those of human blood in accordance with its higher Hb content.

Journal ArticleDOI
TL;DR: Four cases of osteopetrosis, with manifestations within the first months of life, are presented, and Heparin seems to be of no practical value in this disorder.
Abstract: Summary Four cases of osteopetrosis, with manifestations within the first months of life, are presented. The first two cases were siblings. One of them received no therapy, the other 12 blood transfusions and antibiotics. Therapy had no influence on the thrombocytopenia and haemolytic process in Case 2, and he developed rachitic-like changes and a decrease in serum calcium during hospitalization. Both these two siblings died at the age of 5 months. The last two cases have been on prednisone therapy for 21 and 14 months, respectively. Case 3 is now doing well on prednisone, 7.5–10 mg every other day. Her mental and stato-motoric development has so far been normal. Optic nerve decompression was performed in March 1968, and the eye on which the operation was performed still retains some vision. Case 4 was started on steroids when he was about 3 months older than Case 3. Splenectomy had to be performed due to high prednisone requirements, and he still needs prednisone, 15 mg every other day. He seems, unfortunately, to be blind and slightly retarded. Heparin seems to be of no practical value in this disorder. Cellulose phosphate therapy resulted in impaired calcium absorption. The resulting hypocalcemia seems, however, to have very little, if any, effect on the underlying disease.

Journal ArticleDOI
TL;DR: Human y-globulin in the antiserum combined with rheumatoid factor in the tissue and blocked the reaction with other y- globulins or antibodies, so specific anti-y-glOBulin sera free from soluble human serum components were prepared.
Abstract: Antisera t o various human y-globulins are usually prepared by immunizing animals with more or less purified y-globulins [Z, 4, 81. To make the resultant antisera specific for a given y-globulin, they are absorbed with preparations of soluble y-globulins, or other serum proteins, lacking the particular y-globulin fractions. I n addition to the remaining antibodies, such absorbed sera contain excess of the antigens used for absorption, or soluble antigen-antibody complexes or both. These components may interfere in some serological test systems. They were particularly troublesome when using mixed agglutination with tissue sections for the study of rheumatoid factor in tissue [3]. Human y-globulin in the antiserum combined with rheumatoid factor in the tissue and blocked the reaction with other y-globulins or antibodies. Therefore we had to prepare specific anti-y-globulin sera free from soluble human serum components.