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Institution

University of Bologna

EducationBologna, Emilia-Romagna, Italy
About: University of Bologna is a education organization based out in Bologna, Emilia-Romagna, Italy. It is known for research contribution in the topics: Population & Galaxy. The organization has 38387 authors who have published 115176 publications receiving 3460869 citations. The organization is also known as: Università di Bologna & UNIBO.


Papers
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Journal ArticleDOI
TL;DR: Focusing on using probabilistic metrics such as average values or variance to quantify design objectives such as performance and power will lead to a major change in SoC design methodologies.
Abstract: On-chip micronetworks, designed with a layered methodology, will meet the distinctive challenges of providing functionally correct, reliable operation of interacting system-on-chip components. A system on chip (SoC) can provide an integrated solution to challenging design problems in the telecommunications, multimedia, and consumer electronics domains. Much of the progress in these fields hinges on the designers' ability to conceive complex electronic engines under strong time-to-market pressure. Success will require using appropriate design and process technologies, as well as interconnecting existing components reliably in a plug-and-play fashion. Focusing on using probabilistic metrics such as average values or variance to quantify design objectives such as performance and power will lead to a major change in SoC design methodologies. Overall, these designs will be based on both deterministic and stochastic models. Creating complex SoCs requires a modular, component-based approach to both hardware and software design. Despite numerous challenges, the authors believe that developers will solve the problems of designing SoC networks. At the same time, they believe that a layered micronetwork design methodology will likely be the only path to mastering the complexity of future SoC designs.

3,852 citations

Book
10 Mar 2005
TL;DR: This unique reference work is an absolutely essential resource for all biometric security professionals, researchers, and systems administrators.
Abstract: A major new professional reference work on fingerprint security systems and technology from leading international researchers in the field Handbook provides authoritative and comprehensive coverage of all major topics, concepts, and methods for fingerprint security systems This unique reference work is an absolutely essential resource for all biometric security professionals, researchers, and systems administrators

3,821 citations

Journal ArticleDOI
TL;DR: The beneficial effects of inflammation devoted to the neutralization of dangerous/harmful agents early in life and in adulthood become detrimental late in life in a period largely not foreseen by evolution, according to the antagonistic pleiotropy theory of aging.
Abstract: In this paper we extend the “network theory of aging,” and we argue that a global reduction in the capacity to cope with a variety of stressors and a concomitant progressive increase in proinflammatory status are major characteristics of the aging process. This phenomenon, which we will refer to as “inflamm-aging,” is provoked by a continuous antigenic load and stress. On the basis of evolutionary studies, we also argue that the immune and the stress responses are equivalent and that antigens are nothing other than particular types of stressors. We also propose to return macrophage to its rightful place as central actor not only in the inflammatory response and immunity, but also in the stress response. The rate of reaching the threshold of proinflammatory status over which diseases/disabilities ensue and the individual capacity to cope with and adapt to stressors are assumed to be complex traits with a genetic component. Finally, we argue that the persistence of inflammatory stimuli over time represents the biologic background (first hit) favoring the susceptibility to age-related diseases/disabilities. A second hit (absence of robust gene variants and/or presence of frail gene variants) is likely necessary to develop overt organ-specific age-related diseases having an inflammatory pathogenesis, such as atherosclerosis, Alzheimer's disease, osteoporosis, and diabetes. Following this perspective, several paradoxes of healthy centenarians (increase of plasma levels of inflammatory cytokines, acute phase proteins, and coagulation factors) are illustrated and explained. In conclusion, the beneficial effects of inflammation devoted to the neutralization of dangerous/harmful agents early in life and in adulthood become detrimental late in life in a period largely not foreseen by evolution, according to the antagonistic pleiotropy theory of aging.

3,763 citations

Book
01 Nov 1990
TL;DR: This paper focuses on the part of the knapsack problem where the problem of bin packing is concerned and investigates the role of computer codes in the solution of this problem.
Abstract: Introduction knapsack problem bounded knapsack problem subset-sum problem change-making problem multiple knapsack problem generalized assignment problem bin packing problem. Appendix: computer codes.

3,694 citations

Journal ArticleDOI
TL;DR: In this paper, a review of the published evidence for management and/or prevention of a given condition is carried out by experts in the field and a critical evaluation of diagnostic and therapeutic procedures is performed including assessment of the risk/benefit ratio.
Abstract: Guidelines and Expert Consensus Documents summarize and evaluate all currently available evidence on a particular issue with the aim to assist physicians in selecting the best management strategies for a typical patient, suffering from a given condition, taking into account the impact on outcome, as well as the risk/benefit ratio of particular diagnostic or therapeutic means. Guidelines are no substitutes for textbooks. The legal implications of medical guidelines have been discussed previously. A great number of Guidelines and Expert Consensus Documents have been issued in recent years by the European Society of Cardiology (ESC) as well as by other societies and organizations. Because of the impact on clinical practice, quality criteria for development of guidelines have been established in order to make all decisions transparent to the user. The recommendations for formulating and issuing ESC Guidelines and Expert Consensus Documents can be found on the ESC website (http://www.escardio.org/knowledge/guidelines). In brief, experts in the field are selected and undertake a comprehensive review of the published evidence for management and/or prevention of a given condition. Unpublished clinical trial results are not taken into account. A critical evaluation of diagnostic and therapeutic procedures is performed including assessment of the risk/benefit ratio. Estimates of expected health outcomes for larger societies are included, where data exist. The level of evidence and the strength of recommendation of particular treatment options are weighed and graded according to predefined scales, as outlined in Tables 1 and 2 . View this table: Table 1 Classes of recommendations View this table: Table 2 Levels of evidence The experts of the writing panels have provided disclosure statements of all relationships they may have which might be perceived as real or potential sources of conflicts of interest. These disclosure forms are kept on file at the European Heart House, headquarters of the ESC. Any changes in conflict of interest that arise …

3,462 citations


Authors

Showing all 39076 results

NameH-indexPapersCitations
Anil K. Jain1831016192151
H. S. Chen1792401178529
Stefan Schreiber1781233138528
Alvio Renzini16290895452
David H. Adams1551613117783
Roberto Romero1511516108321
Thomas E. Starzl150162591704
Paolo Boffetta148145593876
Kypros H. Nicolaides147130287091
J. Fraser Stoddart147123996083
Fabio Finelli147542111128
Jack Hirsh14673486332
Kjell Fuxe142147989846
Andrew Ivanov142181297390
Peter Lang140113698592
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023398
20221,031
20217,486
20207,098
20196,390
20185,737