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Showing papers by "University of Bordeaux published in 1973"


Journal ArticleDOI
02 Nov 1973-Science
TL;DR: The destruction of ascending noradreniergic pathways by bilateral microinjections of 6-hydroxydopamnine made laterally to the pedunculus cerebellaris superior completely abolished the in vitro synthesis of [3H]norepinephrine from L-tyrosine in slices and in synaptosomes of the rat cortex, providing the first biochemical support for the existence of dopaminergic terminals independent of Noradrenergic terminals in theRat cortex.
Abstract: The destruction of ascending noradreniergic pathways by bilateral microinjections of 6-hydroxydopamnine made laterally to the pedunculus cerebellaris superior completely abolished the in vitro synthesis of [(3)H]norepinephrine from L-[(3)H]tyrosine in slices and in synaptosomes of the rat cortex. However, normal [(3)H]dopamine synthesis could still be observed in both cortical preparations from animals with lesions. These results provide the first biochemical support for the existence of dopaminergic terminals independent of noradrenergic terminals in the rat cortex.

469 citations


Journal ArticleDOI
TL;DR: In this article, an investigation of the sodium-cobalt-oxygen system allows the isolation of four new bronze type phases with the formula Naχ.CoO2 (χ 1).

338 citations



Journal ArticleDOI
TL;DR: The “signs”, i.e. the components, of 275 seizures of 190 children with benign epilepsy associated with Rolandic spikes; 36 signs were listed and it was found that the usual signs were motor though some were sensory.
Abstract: SUMMARY We analyzed the “signs”, i.e. the components, of 275 seizures of 190 children with benign epilepsy associated with Rolandic spikes; 36 signs were listed. Primarily generalized convulsions were rare, occurring in 18% of our series. The other seizures were partial and remained so or became secondarily generalized; the usual signs were motor though some were sensory. In spite of an apparent diversity of seizure patterns, most reflect the preferential localization in the lower banks of the Rolandic fissure, the pre- and postcentral suprasylvian gyri. Tonic or clonic manifestations of half the face, arrest of speech, and oropharyngeal manifestations are the commonest signs. Seizures often occur in sleep; when in the waking state, consciousness is often fully or partially retained. RESUME Nous avons etudie les signes cliniques de 275 crises recueillies chez 190 enfants presentant une epilepsie benigne a paroxysmes rolandiques (E.P.R.); 36 signes ont ete retenus et analyses. Les crises generalisees convulsives primaires, sont rares (18% du nombre total des crises). Dans les autres cas, les crises etaient des crises partielles, restant partielles ou se generalisant secondairement. Ces crises partielles comportent surtout des signes moteurs, accessoirement des signes sensitifs. Malgre une symptomatologie en apparence polymorphe, les crises de ľE.P.R. traduisent de facon evidente la mise en jeu preferentielle de la partie basse, immedia-tement suprasylvienne des gyri pre- et postcentraux. Les manifestations toniques et/ou cloniques ďune hemiface, une impossibilitye de parler, des manifestations oropharyngees en sont les signes les plus habituels et les plus evocateurs. ZUSAMMENFASSUNG Wir analysierten die Befunde d.h. die Komponenten von 275 Anfallen bei 190 Kindern mit benigner Epilepsie, die mit Spitzenpotentialen uber der Rolandischen Region einhergehen; 36 Befunde werden unterschieden. Primar generalisierte Krampfe traten selten auf, bei 18% unserer Serien. Die ubrigen Anfalle waren Partialanfalle und blieben solche oder generalisierten sekundar; sie zeigten gewohn-lich motorische, einige auch sensorische Symptome. Trotz der Verschiedenartigkeit der Anfallsbilder zeigten die meisten einen bevor-zugten Ursprung in den unteren Abschnitten der Rolandischen Furche, dem pra-und postzentralen Gyrus. Die haufigsten Symptome sind tonische oder klonische Manifestationen einer Gesichtshalfte, Sprachverlust und oropharyngeale Manifesta-tionen. Die Anfalle ereignen sich haufig im Schlaf; treten sie im Wachzustand auf, bleibt das Bewustsein oft vollig oder teilweise erhalten. RESUMEN Hemos analizado los “signos”, es decir, los componentes de 275 ataques en 190 ninos con epilepsia benigna asociada a puntas rolandicas y se encontraron 36 signos. Convulsiones generalizadas fueron poco frecuentes ocurriendo en 18% de nuestros casos. El resto de los ataques fueron focales y algunos se generalizaron secundaria-mente y los componentes motores fueron mas comunes que los sensoriales. A pesar de una aparente variedad de los ataques, la mayor parte reflejan una localization preferente por la portion inferior de la fisura de Rolando, en los segmen-tos suprasilvianos de las circunvoluciones pre y postrolandicas. Los signos mas comunes fueron episodios tonicos o clonicos de una hemicara, interruption del lenguaje y manifestaciones orofaringeas. Los ataques son frequentes durante el sueno y cuando ocurren en vigilia el estado de conciencia se mantiene total o par-cialmente.

165 citations


Journal ArticleDOI
TL;DR: In this paper, a new copper (+III) compound, SrLaCuO 4 has been prepared under oxygen pressure and investigated, and it has the K 2 NiF 4 structure (a = 3.765 ± 0.002 A c = 13.27 ±0.02 A).

115 citations



Journal ArticleDOI
TL;DR: In this article, the difference between the magnitudes and thermal evolutions of the magnetic susceptibilities are explained in terms of ferromagnetic vs antiferromagnetic superexchange enhancement and large vs small spin polarons associated with excited states.

75 citations


Journal ArticleDOI
TL;DR: In this paper, the normal modes of characteristic vibrations of cis and trans amide groups are specially discussed, showing the existence of an interaction between oxygen and hydrogen in the amide cis group.

63 citations



Journal ArticleDOI
TL;DR: In this paper, the substitution of organic halides by allylic organotin compounds is described, and the results support a free radical chain mechanism are influence of radical reaction initiators and inhibitors, synthesis of racemic products from an optically active halide, rearrangement of an unstable intermediate free radical, evidence for polar effects and structure-reactivity relationships for the halides.

48 citations


Journal ArticleDOI
TL;DR: In the case of organotin enolates, heating with alkylating agents, usually gives monoalkylated products in very good yields: numerous examples with ketones and aldehydes are described.

Journal ArticleDOI
TL;DR: Nb2Zr6O17 as discussed by the authors is an orthorhombic space group with a = 40.91, b = 4.93, c = 5.27 A. Variations in compositions can be accounted for by increasing or decreasing the number of sevenfold coordinated ions in the structure.

Journal ArticleDOI
TL;DR: In this article, current velocity and suspended sediment concentration measurements at anchor stations in the downstream extremity of Gironde estuary indicate that during periods of high river discharge, a significant amount of suspended sediment is transported out of the estuary onto the adjacent continental shelf.

Journal ArticleDOI
TL;DR: The chromatographic analysis of the volatile leaf oil of Pinus pinaster Ait showed 42% of monoterpene hydrocarbons and 23% of oxygenated compounds including esters (linalyl, bornyl, geranyl, neryl and farnesyl acetates) were also identified as discussed by the authors.

Journal ArticleDOI
TL;DR: In this article, the phase diagram of the system V 1−x Cr x O 2 (0 ⩽ x⩽ 0.15) by magnetic susceptibility and X-ray diffraction measurements was determined.

Journal ArticleDOI
TL;DR: The crystal structure of Ca 2 B 5 O 9 Br has been solved from three-dimensional X-ray counter data (Mo Kα radiation) and refined by least-squares methods, with anisotropic thermal parameters for the heavy atoms, to a conventional agreement factor of R = 0.034.

Journal ArticleDOI
TL;DR: The β-TeVO4 as discussed by the authors octahedra share corners forming puckered sheets parallel to (010) and are held together by [Te2O6]4− groups in which tellurium is one-side coordinated by four oxygen atoms.

Journal ArticleDOI
TL;DR: The failure of DOPS to restore self-stimulation elicited from the LH suggests that noradrenergic neurons in this area are not directly involved in LH self- Stimulation; however, it cannot be excluded that DOPS is not homogeneously distributed in the brain.

Journal ArticleDOI
TL;DR: In this paper, the structure of MgB 4, which is based on chains of boron pentagonal pyramids in which the averaged BB bond is 1.787 A, was established from single crystal data collected on an automatic diffractometer.

Journal ArticleDOI
TL;DR: Imposed or self-stimulation of the area ventralis tegmenti activated the utilization and turnover of NE in structures innervated by both the ventral and dorsal ascending noradrenergic pathways and the dopamine limbic system appeared to be directly activated by self- Stimulation.

Journal ArticleDOI
TL;DR: In this article, a good correlation was found between the frequency of maximum absorption and the ionization potential of the solvent molecules, and the 385 nm transient absorption previously attributed to these charge transfer species was reassigned to I−2 radical anions.

Journal ArticleDOI
TL;DR: In this article, the Me 3 SiClMgHMPT system has been used to synthesize e-diketones from α-ethylenic ketones.

Journal ArticleDOI
TL;DR: It is shown that the overall quantum yield of photoreduction is governed by the second step and can be calculated from the ratio of the rate constants of the two elementary processes involved in this step.
Abstract: — The photoreduction of thiazine dyes by ethylene diamine tetraacetic acid (EDTA) was investigated by Rash photolysis. This reaction was found to occur according to a three-step mechanism. the first being the formation of the dye triplet state followed, in weakly acid solutions, by protonation. During the second step, the triplet state of the dye disappears through two competing processes: spontaneous deactivation and reaction with EDTA, which leads to the semireduced dye. The third step leads to the leucodye. It is shown that the overall quantum yield of photoreduction is governed by the second step and can be calculated from the ratio of the rate constants of the two elementary processes involved in this step. This ratio was measured over a wide pH range.

Journal ArticleDOI
TL;DR: The euroxybiontic regulators Stygocapitella subterranea and Marionina achaeta show highest tolerance to low oxygen tension; this adaptive character enables these species to live at a high level of the sandy beach which is known as an oxygen-deficient habitat.

Journal ArticleDOI
TL;DR: In this article, the behavior of 3-halogenoalkoxy tributyltin with magnesium was investigated, and it was observed in very good yields the formation of 3hydroxyalkyltributyl-ltin by an intramolecular process.

Journal ArticleDOI
TL;DR: In this paper, the coupled monopole and volume-conserving quadrupole oscillations in 4He, 12C, 16O, 20Ne and 40Ca have been studied within the framework of the Hill-Wheeler generator coordinate method.

Book ChapterDOI
01 Jan 1973
TL;DR: In this paper, it is shown how it is possible to generalize many results on controllability of linear control systems to the nonlinear ones, by making use of basic definitions of differential geometry.
Abstract: In these lectures we shall see how it is possible to generalize many results on controllability of linear control systems to the nonlinear ones. A little use of basic definitions of differential geometry is made ; the necessary material used is exposed in appendix.

Journal ArticleDOI
TL;DR: The crystal structure of SrFeF5 has been determined by single crystal X-ray diffraction methods as discussed by the authors, and the unit cell is monoclinic (space group P2 1 c ) with a = 7.062 ± 0.001 A.

Journal ArticleDOI
TL;DR: In this article, a precise structural refinement of ferric oxyfluoride (FeOF) has been carried out by means of singlecrystal diffraction methods, and the structure of this compound, which is of the rutile type, is discussed.

Journal ArticleDOI
TL;DR: The crystal structure of a new boracite Li 4 B 7 O 12 Cl has been solved from three dimensional X-ray counter data (Cu K α radiation) and refined by least-squares methods to a conventional agreement factor of R = 0.031.