Institution
University of Bordeaux
Education•Bordeaux, France•
About: University of Bordeaux is a education organization based out in Bordeaux, France. It is known for research contribution in the topics: Population & Laser. The organization has 28811 authors who have published 55536 publications receiving 1619635 citations. The organization is also known as: UB.
Topics: Population, Laser, Raman spectroscopy, Polymerization, Crystal structure
Papers published on a yearly basis
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310 citations
Vanderbilt University Medical Center1, Vanderbilt University2, University of Pennsylvania3, National Institute for Health Research4, Queen Mary University of London5, Veterans Health Administration6, Emory University7, VA Boston Healthcare System8, Imperial College London9, University of Ioannina10, University of Leicester11, University of Bordeaux12, University of Michigan13, University of Cambridge14, McMaster University15, COMSATS Institute of Information Technology16, University of Dundee17, University of Newcastle18, Lund University19, Leiden University Medical Center20, University Medical Center Groningen21, University of Edinburgh22, King's College London23, Guy's and St Thomas' NHS Foundation Trust24, University of Texas Health Science Center at Houston25, University of Liverpool26, Broad Institute27, Boston University28, University of London29, University of Bristol30, Washington University in St. Louis31, university of lille32, Wellcome Trust Centre for Human Genetics33, University of Eastern Finland34, Wellcome Trust Sanger Institute35, National Institutes of Health36, Population Health Research Institute37, Brigham and Women's Hospital38, University of Sassari39, Wellcome Trust40, University of Oxford41, Harokopio University42, University of Washington43, Harvard University44, VA Palo Alto Healthcare System45, Stanford University46
TL;DR: Analysis of blood pressure data from the Million Veteran Program trans-ethnic cohort identifies common and rare variants, and genetically predicted gene expression across multiple tissues associated with systolic, diastolic and pulse pressure in over 775,000 individuals.
Abstract: In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood pressure SNPs and 53 rare variants in genome-wide association studies of systolic, diastolic and pulse pressure in up to 776,078 participants from the Million Veteran Program (MVP) and collaborating studies, with analysis of the blood pressure clinical phenome in MVP. Our transcriptome-wide association study detected 4,043 blood pressure associations with genetically predicted gene expression of 840 genes in 45 tissues, and mouse renal single-cell RNA sequencing identified upregulated blood pressure genes in kidney tubule cells.
310 citations
TL;DR: The results of this study do not support using the presence or absence of hot flushes or the pharmacogenetic testing of CYP2D6 to determine whether to treat postmenopausal breast cancer patients with tamoxifen and support the hypothesis that reduced enzyme activity was associated with worse disease control.
Abstract: Background
Adjuvant tamoxifen therapy is effective for postmenopausal women with endocrine-responsive breast cancer. Cytochrome P450 2D6 (CYP2D6) enzyme metabolizes tamoxifen to clinically active metabolites, and CYP2D6 polymorphisms may adversely affect tamoxifen efficacy. In this study, we investigated the clinical relevance of CYP2D6 polymorphisms.
310 citations
TL;DR: Results showed that injections of amphetamine into the nucleus accumbens induced a dose-dependent increase in locomotor activity which remained identical with the repetition of the injections, whereas no difference between the different intra-accumbens pretreated groups was observed following the diverse phosphate-buffered saline solution and amphetamine challenges.
310 citations
TL;DR: A novel octafunctional calixarene derivative, namely, 5,11,17,23,29,35,41,47-octa-tertbutyl-49,50,51,52,53,54,55,56-octakis(2-bromopropionyloxy)calix[8]arene (1) which was readily synthesized in one step, was used to initiate the bulk atom transfer radical polymerization (ATRP) of styrene, at 100 °C, in the presence of CuBr/
Abstract: A novel octafunctional calixarene derivative, namely, 5,11,17,23,29,35,41,47-octa-tert-butyl-49,50,51,52,53,54,55,56-octakis(2-bromopropionyloxy)calix[8]arene (1) which was readily synthesized in one step, was used to initiate the bulk atom transfer radical polymerization (ATRP) of styrene, at 100 °C, in the presence of CuBr/2,2‘-bipyridyl. Polystyrene (PS) stars of narrow polydispersity with precisely eight arms could be synthesized by restricting the polymerization to low conversion, typically below 15−20%. At higher conversions, irreversible coupling occurred between stars as evidenced by a size exclusion chromatography line equipped with a multiangle laser light scattering detector (MALLS/SEC). Octafunctional stars of molar masses up to 340 000 g mol-1 could be prepared by using high ratios of the monomer to the initiator ([M]/[I] = 12 000). The precise octafunctional structure of the stars was confirmed, on one hand, by studying the kinetics of ATRP of styrene initiated by an equimolar mixture of 1 a...
310 citations
Authors
Showing all 28995 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Nicholas G. Martin | 192 | 1770 | 161952 |
| George F. Koob | 171 | 935 | 112521 |
| Daniel J. Jacob | 162 | 656 | 76530 |
| Arthur W. Toga | 159 | 1184 | 109343 |
| James M. Tour | 143 | 859 | 91364 |
| Floyd E. Bloom | 139 | 616 | 72641 |
| Herbert Y. Meltzer | 137 | 1148 | 81371 |
| Jean-Marie Tarascon | 136 | 853 | 137673 |
| Stanley Nattel | 132 | 778 | 65700 |
| Michel Haïssaguerre | 117 | 757 | 62284 |
| Liquan Chen | 111 | 689 | 44229 |
| Marion Leboyer | 110 | 773 | 50767 |
| Jean-François Dartigues | 106 | 631 | 46682 |
| Alexa S. Beiser | 106 | 366 | 47457 |
| Robert Dantzer | 105 | 497 | 46554 |