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Institution

University of Bordeaux

EducationBordeaux, France
About: University of Bordeaux is a education organization based out in Bordeaux, France. It is known for research contribution in the topics: Population & Laser. The organization has 28811 authors who have published 55536 publications receiving 1619635 citations. The organization is also known as: UB.


Papers
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Journal ArticleDOI
TL;DR: The study shows that the conditioned proboscis extension response assay can be used for estimating sublethal effects of pesticides on bees and comparisons of sensitivity as well as the estimation of NOECs, useful for regulatory purposes, are possible.
Abstract: Using a conditioned proboscis extension response (PER) assay, honeybees (Apis mellifera L.) can be trained to associate an odor stimulus with a sucrose reward. Previous studies have shown that observations of conditioned PER were of interest for assessing the behavioral effects of pesticides on the honeybee. In the present study, the effects of sublethal concentrations of nine pesticides on learning performances of worker bees subjected to the PER assay were estimated and compared. Pesticides were tested at three concentrations. The highest concentration of each pesticide corresponded to the median lethal dose value (48-h oral LD50), received per bee and per day, divided by 20. Reduced learning performances were observed for bees surviving treatment with fipronil, deltamethrin, endosulfan, and prochloraz. A lack of behavioral effects after treatment with lambda-cyalothrin, cypermethrin, tau-fluvalinate, triazamate, and dimethoate was recorded. No-observed-effect concentrations (NOECs) for the conditioned PER were derived for the studied pesticides. Our study shows that the PER assay can be used for estimating sublethal effects of pesticides on bees. Furthermore, comparisons of sensitivity as well as the estimation of NOECs, useful for regulatory purposes, are possible.

259 citations

Journal ArticleDOI
Yousef Abou El-Neaj1, Cristiano Alpigiani2, Sana Amairi-Pyka3, Henrique Araujo4, Antun Balaž5, Angelo Bassi6, Lars Bathe-Peters7, Baptiste Battelier8, Aleksandar Belić5, Elliot Bentine9, Jose Bernabeu10, Andrea Bertoldi8, Robert Bingham11, Robert Bingham12, Diego Blas13, Vasiliki Bolpasi14, Kai Bongs15, Sougato Bose16, Philippe Bouyer8, T. J. V. Bowcock17, William B. Bowden18, Oliver Buchmueller4, Clare Burrage19, Xavier Calmet20, Benjamin Canuel8, Laurentiu Ioan Caramete, Andrew Carroll17, Giancarlo Cella6, Vassilis Charmandaris14, S. Chattopadhyay21, S. Chattopadhyay22, Xuzong Chen23, Maria Luisa Chiofalo24, J. P. Coleman17, J. P. Cotter4, Y. Cui25, Andrei Derevianko26, Albert De Roeck27, Goran S. Djordjevic28, P. J. Dornan4, Michael Doser27, Ioannis Drougkakis14, Jacob Dunningham20, Ioana Dutan, Sajan Easo12, G. Elertas17, John Ellis13, John Ellis29, John Ellis27, Mai El Sawy30, Mai El Sawy31, Farida Fassi, D. Felea, Chen Hao Feng8, R. L. Flack16, Christopher J. Foot9, Ivette Fuentes19, Naceur Gaaloul32, A. Gauguet33, Remi Geiger34, Valerie Gibson35, Gian F. Giudice27, J. Goldwin15, O. A. Grachov36, Peter W. Graham37, Dario Grasso24, Maurits van der Grinten12, Mustafa Gündoğan3, Martin G. Haehnelt35, Tiffany Harte35, Aurélien Hees34, Richard Hobson18, Jason M. Hogan37, Bodil Holst38, Michael Holynski15, Mark A. Kasevich37, Bradley J. Kavanagh39, Wolf von Klitzing14, Tim Kovachy40, Benjamin Krikler41, Markus Krutzik3, Marek Lewicki13, Marek Lewicki42, Yu-Hung Lien16, Miaoyuan Liu23, Giuseppe Gaetano Luciano6, Alain Magnon43, Mohammed Mahmoud44, Sudhir Malik4, Christopher McCabe13, J. W. Mitchell22, Julia Pahl3, Debapriya Pal14, Saurabh Pandey14, Dimitris G. Papazoglou45, Mauro Paternostro46, Bjoern Penning47, Achim Peters3, Marco Prevedelli48, Vishnupriya Puthiya-Veettil49, J. J. Quenby4, Ernst M. Rasel32, Sean Ravenhall9, Jack Ringwood17, Albert Roura50, D. O. Sabulsky8, M. Sameed51, Ben Sauer4, Stefan A. Schäffer52, Stephan Schiller53, Vladimir Schkolnik3, Dennis Schlippert32, Christian Schubert32, Haifa Rejeb Sfar, Armin Shayeghi54, Ian Shipsey9, Carla Signorini24, Yeshpal Singh15, Marcelle Soares-Santos47, Fiodor Sorrentino6, T. J. Sumner4, Konstantinos Tassis14, S. Tentindo55, Guglielmo M. Tino56, Guglielmo M. Tino6, Jonathan N. Tinsley56, James Unwin57, Tristan Valenzuela12, Georgios Vasilakis14, Ville Vaskonen29, Ville Vaskonen13, Christian Vogt58, Alex Webber-Date17, André Wenzlawski59, Patrick Windpassinger59, Marian Woltmann58, Efe Yazgan60, Ming Sheng Zhan60, Xinhao Zou8, Jure Zupan61 
Harvard University1, University of Washington2, Humboldt University of Berlin3, Imperial College London4, University of Belgrade5, Istituto Nazionale di Fisica Nucleare6, Technical University of Berlin7, University of Bordeaux8, University of Oxford9, University of Valencia10, University of Strathclyde11, Rutherford Appleton Laboratory12, King's College London13, Foundation for Research & Technology – Hellas14, University of Birmingham15, University College London16, University of Liverpool17, National Physical Laboratory18, University of Nottingham19, University of Sussex20, Fermilab21, Northern Illinois University22, Peking University23, University of Pisa24, University of California, Riverside25, University of Nevada, Reno26, CERN27, University of Niš28, National Institute of Chemical Physics and Biophysics29, Beni-Suef University30, British University in Egypt31, Leibniz University of Hanover32, Paul Sabatier University33, University of Paris34, University of Cambridge35, Wayne State University36, Stanford University37, University of Bergen38, University of Amsterdam39, Northwestern University40, University of Bristol41, University of Warsaw42, University of Illinois at Urbana–Champaign43, Fayoum University44, University of Crete45, Queen's University Belfast46, Brandeis University47, University of Bologna48, Cochin University of Science and Technology49, German Aerospace Center50, University of Manchester51, University of Copenhagen52, University of Düsseldorf53, University of Vienna54, Florida State University55, University of Florence56, University of Illinois at Chicago57, University of Bremen58, University of Mainz59, Chinese Academy of Sciences60, University of Cincinnati61
TL;DR: The Atomic Experiment for Dark Matter and Gravity Exploration (AEDGE) as mentioned in this paper is a space experiment using cold atoms to search for ultra-light dark matter, and to detect gravitational waves in the frequency range between the most sensitive ranges of LISA and the terrestrial LIGO/Virgo/KAGRA/INDIGO experiments.
Abstract: We propose in this White Paper a concept for a space experiment using cold atoms to search for ultra-light dark matter, and to detect gravitational waves in the frequency range between the most sensitive ranges of LISA and the terrestrial LIGO/Virgo/KAGRA/INDIGO experiments. This interdisciplinary experiment, called Atomic Experiment for Dark Matter and Gravity Exploration (AEDGE), will also complement other planned searches for dark matter, and exploit synergies with other gravitational wave detectors. We give examples of the extended range of sensitivity to ultra-light dark matter offered by AEDGE, and how its gravitational-wave measurements could explore the assembly of super-massive black holes, first-order phase transitions in the early universe and cosmic strings. AEDGE will be based upon technologies now being developed for terrestrial experiments using cold atoms, and will benefit from the space experience obtained with, e.g., LISA and cold atom experiments in microgravity.

259 citations

Journal ArticleDOI
TL;DR: These guidelines deal specifically with the following achalasia issues: Diagnostic workup, Definition of the disease, Severity of presentation, Medical treatment, Botulinum Toxin injection, Pneumatic dilatation, POEM, Other endoscopic treatments, Laparoscopic myotomy, definition of recurrence, Follow up and risk of cancer.
Abstract: Achalasia is a relatively rare primary motor esophageal disorder, characterized by absence of relaxations of the lower esophageal sphincter and of peristalsis along the esophageal body As a result, patients typically present with dysphagia, regurgitation and occasionally chest pain, pulmonary complication and malnutrition New diagnostic methodologies and therapeutic techniques have been recently added to the armamentarium for treating achalasia With the aim to offer clinicians and patients an up-to-date framework for making informed decisions on the management of this disease, the International Society for Diseases of the Esophagus Guidelines proposed and endorsed the Esophageal Achalasia Guidelines (I-GOAL) The guidelines were prepared according the Appraisal of Guidelines for Research and Evaluation (AGREE-REX) tool, accredited for guideline production by NICE UK A systematic literature search was performed and the quality of evidence and the strength of recommendations were graded according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Given the relative rarity of this disease and the paucity of high-level evidence in the literature, this process was integrated with a three-step process of anonymous voting on each statement (DELPHI) Only statements with an approval rate >80% were accepted in the guidelines Fifty-one experts from 11 countries and 3 representatives from patient support associations participated to the preparations of the guidelines These guidelines deal specifically with the following achalasia issues: Diagnostic workup, Definition of the disease, Severity of presentation, Medical treatment, Botulinum Toxin injection, Pneumatic dilatation, POEM, Other endoscopic treatments, Laparoscopic myotomy, Definition of recurrence, Follow up and risk of cancer, Management of end stage achalasia, Treatment options for failure, Achalasia in children, Achalasia secondary to Chagas' disease

259 citations

Journal ArticleDOI
TL;DR: Using combined genetic and pharmacological approaches in mice, it is found that ventral striatal CB1 receptors exerted a hypophagic action through inhibition of GABAergic transmission, and brainCB1 receptors modulating excitatory transmission mediated the well-known orexigenic effects of cannabinoids.
Abstract: Cannabinoid signaling is generally thought to increase food intake Bellocchio et al show that cannabinoids can increase or attenuate feeding after a fast, depending on whether they act on glutamatergic forebrain or GABAergic ventral striatal neurons

258 citations


Authors

Showing all 28995 results

NameH-indexPapersCitations
Nicholas G. Martin1921770161952
George F. Koob171935112521
Daniel J. Jacob16265676530
Arthur W. Toga1591184109343
James M. Tour14385991364
Floyd E. Bloom13961672641
Herbert Y. Meltzer137114881371
Jean-Marie Tarascon136853137673
Stanley Nattel13277865700
Michel Haïssaguerre11775762284
Liquan Chen11168944229
Marion Leboyer11077350767
Jean-François Dartigues10663146682
Alexa S. Beiser10636647457
Robert Dantzer10549746554
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202378
2022393
20213,110
20203,362
20193,245
20183,143