scispace - formally typeset
Search or ask a question
Institution

University of Bordeaux

EducationBordeaux, France
About: University of Bordeaux is a education organization based out in Bordeaux, France. It is known for research contribution in the topics: Population & Laser. The organization has 28811 authors who have published 55536 publications receiving 1619635 citations. The organization is also known as: UB.


Papers
More filters
Journal ArticleDOI
02 May 1991-Nature
TL;DR: Under an identified neuromodulatory stimulus, the CPG that produces swallowing-like behaviour of the foregut in lobsters is constructed de novo from neurons belonging to other CPGs, demonstrating that a modulatory input can specify an appropriate CPG from a pool of individual neurons of diverse origins.
Abstract: RHYTHMIC motor behaviours are generated within the central nervous system by neuronal circuits called central pattern generators (CPG)1. Although a CPG can produce several forms of the same behaviour2–5 and several circuits may interact to generate different behaviours6, it is generally assumed that a given CPG consists of a predefined assemblage of neurons that is functionally distinguishable from other circuits. However, recent studies on the stomatogastric nervous system of Crustacea have suggested that CPGs may not be immutable functional entities7–10. We now report that under an identified neuromodulatory stimulus, the CPG that produces swallowing-like behaviour of the foregut in lobsters is constructed de novo from neurons belonging to other CPGs. Consequently neurons operating independently as members of different circuits may be reconfigured into a new pattern-generating circuit that operates differently from the original circuits. This not only challenges the concept of the CPG being a discrete functional entity, but also demonstrates that a modulatory input can specify an appropriate CPG from a pool of individual neurons of diverse origins.

235 citations

Journal ArticleDOI
A. A. Abdo1, A. A. Abdo2, Markus Ackermann3, Marco Ajello3  +195 moreInstitutions (37)
TL;DR: In this paper, the Fermi Large Area Telescope was used to measure the gamma-ray emission in the second Galactic quadrant at 100 deg < l < 145 deg and -15 deg < b < +30 deg.
Abstract: We present the analysis of the interstellar gamma-ray emission measured by the Fermi Large Area Telescope toward a region in the second Galactic quadrant at 100 deg < l < 145 deg and -15 deg < b < +30 deg. This region encompasses the prominent Gould-Belt clouds of Cassiopeia, Cepheus and the Polaris flare, as well as atomic and molecular complexes at larger distances, like that associated with NGC 7538 in the Perseus arm. The good kinematic separation in velocity between the local, Perseus, and outer arms, and the presence of massive complexes in each of them make this region well suited to probe cosmic rays and the interstellar medium beyond the solar circle. The gamma-ray emissivity spectrum of the gas in the Gould Belt is consistent with expectations based on the locally measured cosmic-ray spectra. The gamma-ray emissivity decreases from the Gould Belt to the Perseus arm, but the measured gradient is flatter than expectations for cosmic-ray sources peaking in the inner Galaxy as suggested by pulsars. The Xco=N(H2)/W(CO) conversion factor is found to increase from (0.87 +- 0.05) 10^20 cm^-2 (K km s^-1)^-1 in the Gould Belt to (1.9 +- 0.2) 10^20 cm^-2 (K km s^-1)^-1 in the Perseus arm. We derive masses for the molecular clouds under study. Dark gas, not properly traced by radio and microwave surveys, is detected in the Gould Belt through a correlated excess of dust and gamma-ray emission: its mass amounts to ~50% of the CO-traced mass.

235 citations

Journal ArticleDOI
TL;DR: Although the reservoir is well known, the routes of infection are still poorly understood: Are they oral-oral or fecal-oral?

235 citations

Journal ArticleDOI
TL;DR: Exome sequencing identified recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 activation, and cell proliferation sensitive to Src inhibitors and β-catenin mutation as an early alteration and TERT promoter mutations as associated with the last step of the adenoma-carcinoma transition.

234 citations

Journal ArticleDOI
TL;DR: In this paper, the authors investigate the 2013/2014 winter wave conditions that severely impacted the Atlantic coast of Europe and demonstrate that this winter was the most energetic along most of the Atlantic Coast of Europe since at least 1948.
Abstract: Studies of coastal vulnerability due to climate change tend to focus on the consequences of sea level rise, rather than the complex coastal responses resulting from changes to the extreme wave climate. Here we investigate the 2013/2014 winter wave conditions that severely impacted the Atlantic coast of Europe and demonstrate that this winter was the most energetic along most of the Atlantic coast of Europe since at least 1948. Along exposed open-coast sites, extensive beach and dune erosion occurred due to offshore sediment transport. More sheltered sites experienced less erosion and one of the sites even experienced accretion due to beach rotation induced by alongshore sediment transport. Storm wave conditions such as were encountered during the 2013/2014 winter have the potential to dramatically change the equilibrium state (beach gradient, coastal alignment, and nearshore bar position) of beaches along the Atlantic coast of Europe.

234 citations


Authors

Showing all 28995 results

NameH-indexPapersCitations
Nicholas G. Martin1921770161952
George F. Koob171935112521
Daniel J. Jacob16265676530
Arthur W. Toga1591184109343
James M. Tour14385991364
Floyd E. Bloom13961672641
Herbert Y. Meltzer137114881371
Jean-Marie Tarascon136853137673
Stanley Nattel13277865700
Michel Haïssaguerre11775762284
Liquan Chen11168944229
Marion Leboyer11077350767
Jean-François Dartigues10663146682
Alexa S. Beiser10636647457
Robert Dantzer10549746554
Network Information
Related Institutions (5)
University of Paris
174.1K papers, 5M citations

97% related

Centre national de la recherche scientifique
382.4K papers, 13.6M citations

97% related

Pierre-and-Marie-Curie University
56.1K papers, 2.3M citations

97% related

École Normale Supérieure
99.4K papers, 3M citations

95% related

Katholieke Universiteit Leuven
176.5K papers, 6.2M citations

94% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202378
2022393
20213,110
20203,362
20193,245
20183,143