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Institution

University of Bordeaux

EducationBordeaux, France
About: University of Bordeaux is a education organization based out in Bordeaux, France. It is known for research contribution in the topics: Population & Laser. The organization has 28811 authors who have published 55536 publications receiving 1619635 citations. The organization is also known as: UB.


Papers
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Journal ArticleDOI
TL;DR: Treatment of Cushing's syndrome is essential to reduce mortality and associated comorbidities and the choice of second-line treatments, including medication, bilateral adrenalectomy, and radiation therapy, must be individualized to each patient.
Abstract: Objective: The objective is to formulate clinical practice guidelines for treating Cushing's syndrome. Participants: Participants include an Endocrine Society-appointed Task Force of experts, a methodologist, and a medical writer. The European Society for Endocrinology co-sponsored the guideline. Evidence: The Task Force used the Grading of Recommendations, Assessment, Development, and Evaluation system to describe the strength of recommendations and the quality of evidence. The Task Force commissioned three systematic reviews and used the best available evidence from other published systematic reviews and individual studies. Consensus Process: The Task Force achieved consensus through one group meeting, several conference calls, and numerous e-mail communications. Committees and members of The Endocrine Society and the European Society of Endocrinology reviewed and commented on preliminary drafts of these guidelines. Conclusions: Treatment of Cushing's syndrome is essential to reduce mortality and associ...

838 citations

Journal ArticleDOI
TL;DR: The present review did not consider cyclic, seasonal, irritable-dysphoric or otherwise impulse-ridden, intermittently explosive or agitated psychiatric conditions for which the bipolar connection is less established.

837 citations

Journal ArticleDOI
TL;DR: The aim of this retrospective study was to evaluate the risk factors for clinical anastomotic leakage after anterior resection for cancer of the rectum.
Abstract: Background The most important surgical complication following rectal resection with anastomosis is symptomatic anastomotic leakage. which is associated with a 6-22 per cent mortality rate. The aim of this retrospective study was to evaluate the risk factors for clinical anastomotic leakage after anterior resection for cancer of the rectum. Methods From 1980 to 1995, 272 consecutive anterior resections for rectal cancer were performed by the same surgical team; 131 anastomoses were situated 5 cm or less from the anal verge. The associations between clinical anastomotic leakage and 19 patient-, tumour-, surgical- and treatment-related variables were studied by univariate and multivariate analysis. Results The rate of clinical anastomotic leakage was 12 per cent (32 of 272). Multivariate analysis of the overall population showed that only male sex and level of anastomosis were independent factors for development of anastomotic leakage. The risk of leakage was 6.5 times higher for anastomoses situated less than 5 cm from the anal verge than for those situated above 5 cm; it was 2.7 times higher for men than for women. In a second analysis of low anastomoses (5 cm or less from the anal verge; = 131), obesity was statistically associated with leakage. Conclusion A protective stoma is suitable after sphincter-saving resection for rectal cancer for anastomoses situated at or less than 5 cm from the anal verge, particularly for men and obese patients.

837 citations

Journal ArticleDOI
TL;DR: A characterization of electrochemically deintercalated nanomaterials by X-ray diffraction and electron microscopy that shows the coexistence of fully intercalated and fully deIntercalated individual particles indicates that the growth reaction is considerably faster than its nucleation.
Abstract: Lithium iron phosphate is one of the most promising positive-electrode materials for the next generation of lithium-ion batteries that will be used in electric and plug-in hybrid vehicles. Lithium deintercalation (intercalation) proceeds through a two-phase reaction between compositions very close to LiFePO(4) and FePO(4). As both endmember phases are very poor ionic and electronic conductors, it is difficult to understand the intercalation mechanism at the microscopic scale. Here, we report a characterization of electrochemically deintercalated nanomaterials by X-ray diffraction and electron microscopy that shows the coexistence of fully intercalated and fully deintercalated individual particles. This result indicates that the growth reaction is considerably faster than its nucleation. The reaction mechanism is described by a 'domino-cascade model' and is explained by the existence of structural constraints occurring just at the reaction interface: the minimization of the elastic energy enhances the deintercalation (intercalation) process that occurs as a wave moving through the entire crystal. This model opens new perspectives in the search for new electrode materials even with poor ionic and electronic conductivities.

830 citations

Journal ArticleDOI
Th. de Graauw1, Th. de Graauw2, Frank Helmich2, Thomas G. Phillips3  +176 moreInstitutions (20)
TL;DR: The Heterodyne Instrument for the Far-Infrared (HIFI) was launched onboard ESA's Herschel Space Observatory in May 2009 as mentioned in this paper, which is a set of 7 heterodyne receivers that are electronically tuneable, covering 480-1250 GHz with SIS mixers and the 1410-1910 GHz range with hot electron bolometer mixers.
Abstract: Aims. This paper describes the Heterodyne Instrument for the Far-Infrared (HIFI) that was launched onboard ESA's Herschel Space Observatory in May 2009. Methods. The instrument is a set of 7 heterodyne receivers that are electronically tuneable, covering 480-1250 GHz with SIS mixers and the 1410-1910 GHz range with hot electron bolometer (HEB) mixers. The local oscillator (LO) subsystem comprises a Ka-band synthesizer followed by 14 chains of frequency multipliers and 2 chains for each frequency band. A pair of auto-correlators and a pair of acousto-optical spectrometers process the two IF signals from the dual-polarization, single-pixel front-ends to provide instantaneous frequency coverage of 2 × 4 GHz, with a set of resolutions (125 kHz to 1 MHz) that are better than 0.1 km s-1. Results. After a successful qualification and a pre-launch TB/TV test program, the flight instrument is now in-orbit and completed successfully the commissioning and performance verification phase. The in-orbit performance of the receivers matches the pre-launch sensitivities. We also report on the in-orbit performance of the receivers and some first results of HIFI's operations.

828 citations


Authors

Showing all 28995 results

NameH-indexPapersCitations
Nicholas G. Martin1921770161952
George F. Koob171935112521
Daniel J. Jacob16265676530
Arthur W. Toga1591184109343
James M. Tour14385991364
Floyd E. Bloom13961672641
Herbert Y. Meltzer137114881371
Jean-Marie Tarascon136853137673
Stanley Nattel13277865700
Michel Haïssaguerre11775762284
Liquan Chen11168944229
Marion Leboyer11077350767
Jean-François Dartigues10663146682
Alexa S. Beiser10636647457
Robert Dantzer10549746554
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202378
2022393
20213,110
20203,362
20193,245
20183,143