Institution
University of Brighton
Education•Brighton, United Kingdom•
About: University of Brighton is a education organization based out in Brighton, United Kingdom. It is known for research contribution in the topics: Context (language use) & Population. The organization has 4100 authors who have published 9959 publications receiving 277829 citations. The organization is also known as: Brighton University.
Papers published on a yearly basis
Papers
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Gregory A. Roth1, Gregory A. Roth2, Degu Abate3, Kalkidan Hassen Abate4 +1025 more•Institutions (333)
TL;DR: Non-communicable diseases comprised the greatest fraction of deaths, contributing to 73·4% (95% uncertainty interval [UI] 72·5–74·1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional causes accounted for 18·6% (17·9–19·6), and injuries 8·0% (7·7–8·2).
5,211 citations
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TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) as discussed by the authors was used to estimate the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015.
5,050 citations
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TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
4,804 citations
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TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Abstract: The rapid recognition of intravenously injected colloidal carriers, such as liposomes and polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development for "Kupffer cell-evading" or long-circulating particles. Such carriers have applications in vascular drug delivery and release, site-specific targeting (passive as well as active targeting), as well as transfusion medicine. In this article we have critically reviewed and assessed the rational approaches in the design as well as the biological performance of such constructs. For engineering and design of long-circulating carriers, we have taken a lead from nature. Here, we have explored the surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition. Our analysis is then centered where such strategies have been translated and fabricated to design a wide range of particulate carriers (e.g., nanospheres, liposomes, micelles, oil-in-water emulsions) with prolonged circulation and/or target specificity. With regard to the targeting issues, attention is particularly focused on the importance of physiological barriers and disease states.
3,413 citations
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TL;DR: In this article, the results of numerical simulations of nonlinear gravitational clustering in universes dominated by weakly interacting, cold dark matter are presented and the evolution of the fundamental statistical properties of the models is described and their comparability with observation is discussed.
Abstract: The results of numerical simulations of nonlinear gravitational clustering in universes dominated by weakly interacting, 'cold' dark matter are presented. The numerical methods used and the way in which initial conditions were generated are described, and the simulations performed are catalogued. The evolution of the fundamental statistical properties of the models is described and their comparability with observation is discussed. Graphical comparisons of these open models with the observed galaxy distribution in a large redshift survey are made. It is concluded that a model with a cosmological density parameter omega equal to one is quite unacceptable if galaxies trace the mass distribution, and that models with omega of roughly two, while better, still do not provide a fully acceptable match with observation. Finally, a situation in which galaxy formation is suppressed except in sufficiently dense regions is modelled which leads to models which can agree with observation quite well even for omega equal to one.
3,037 citations
Authors
Showing all 4179 results
Name | H-index | Papers | Citations |
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Carlos S. Frenk | 165 | 799 | 140345 |
Csaba Szabó | 123 | 958 | 61791 |
Andrew M. Jones | 103 | 764 | 37253 |
Luigi Ambrosio | 93 | 761 | 39688 |
Stephen J. Ball | 92 | 404 | 46764 |
Georgina M. Mace | 91 | 265 | 53514 |
Gwendolen Jull | 87 | 410 | 26556 |
Paul H. Harvey | 87 | 254 | 37475 |
Alan R. Lehmann | 87 | 259 | 24463 |
John D. Barrow | 87 | 527 | 28333 |
Tom L. Blundell | 86 | 687 | 56613 |
Andrew R. Liddle | 85 | 402 | 66579 |
Julie M. Cunningham | 83 | 371 | 27090 |
James Chapman | 82 | 483 | 36468 |
Seb Oliver | 81 | 302 | 25947 |