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University of Bristol

EducationBristol, United Kingdom
About: University of Bristol is a(n) education organization based out in Bristol, United Kingdom. It is known for research contribution in the topic(s): Population & Poison control. The organization has 44253 authors who have published 113186 publication(s) receiving 4947181 citation(s). The organization is also known as: Bris.. more


Showing all 44253 results

Walter C. Willett3342399413322
George Davey Smith2242540248373
Mika Kivimäki1661515141468
Gavin Davies1592036149835
George D. Yancopoulos15849693955
Pete Smith1562464138819
Marjo-Riitta Järvelin156923100939
Naveed Sattar1551326116368
Matthias Egger152901184176
Susan E. Hankinson15178988297
Debbie A Lawlor1471114101123
Shah Ebrahim14673396807
Christopher Hill1441562128098
Alan J. Silman14170892864
Barry Blumenfeld1401909105694

Open accessJournal ArticleDOI: 10.1136/BMJ.315.7109.629
13 Sep 1997-BMJ
Abstract: Objective: Funnel plots (plots of effect estimates against sample size) may be useful to detect bias in meta-analyses that were later contradicted by large trials. We examined whether a simple test of asymmetry of funnel plots predicts discordance of results when meta-analyses are compared to large trials, and we assessed the prevalence of bias in published meta-analyses. Design: Medline search to identify pairs consisting of a meta-analysis and a single large trial (concordance of results was assumed if effects were in the same direction and the meta-analytic estimate was within 30% of the trial); analysis of funnel plots from 37 meta-analyses identified from a hand search of four leading general medicine journals 1993-6 and 38 meta-analyses from the second 1996 issue of the Cochrane Database of Systematic Reviews . Main outcome measure: Degree of funnel plot asymmetry as measured by the intercept from regression of standard normal deviates against precision. Results: In the eight pairs of meta-analysis and large trial that were identified (five from cardiovascular medicine, one from diabetic medicine, one from geriatric medicine, one from perinatal medicine) there were four concordant and four discordant pairs. In all cases discordance was due to meta-analyses showing larger effects. Funnel plot asymmetry was present in three out of four discordant pairs but in none of concordant pairs. In 14 (38%) journal meta-analyses and 5 (13%) Cochrane reviews, funnel plot asymmetry indicated that there was bias. Conclusions: A simple analysis of funnel plots provides a useful test for the likely presence of bias in meta-analyses, but as the capacity to detect bias will be limited when meta-analyses are based on a limited number of small trials the results from such analyses should be treated with considerable caution. Key messages Systematic reviews of randomised trials are the best strategy for appraising evidence; however, the findings of some meta-analyses were later contradicted by large trials Funnel plots, plots of the trials9 effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials Funnel plot asymmetry was found in 38% of meta-analyses published in leading general medicine journals and in 13% of reviews from the Cochrane Database of Systematic Reviews Critical examination of systematic reviews for publication and related biases should be considered a routine procedure more

Topics: Funnel plot (73%), Publication bias (58%), Meta-analysis (55%)

31,295 Citations

Open accessBook
Michael P. Allen1, D. J. TildesleyInstitutions (1)
11 Feb 1988-
Abstract: Introduction Statistical mechanics Molecular dynamics Monte Carlo methods Some tricks of the trade How to analyse the results Advanced simulation techniques Non-equilibrium molecular dynamics Brownian dynamics Quantum simulations Some applications Appendix A: Computers and computer simulation Appendix B: Reduced units Appendix C: Calculation of forces and torques Appendix D: Fourier transforms Appendix E: The gear predictor - corrector Appendix F: Programs on microfiche Appendix G: Random numbers References Index. more

20,549 Citations

Open accessJournal ArticleDOI: 10.1136/BMJ.D5928
18 Oct 2011-BMJ
Abstract: Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate more

16,113 Citations

Book ChapterDOI: 10.4324/9780203505984-16
Henri Tajfel1, John C. Turner2Institutions (2)
09 Jan 2004-
Abstract: This chapter presents an outline of a theory of intergroup conflict and some preliminary data relating to the theory. Much of the work on the social psychology of intergroup relations has focused on patterns of individual prejudices and discrimination and on the motivational sequences of interpersonal interaction. The intensity of explicit intergroup conflicts of interests is closely related in human cultures to the degree of opprobrium attached to the notion of "renegade" or "traitor." The basic and highly reliable finding is that the trivial, ad hoc intergroup categorization leads to in-group favoritism and discrimination against the out-group. Many orthodox definitions of "social groups" are unduly restrictive when applied to the context of intergroup relations. The equation of social competition and intergroup conflict rests on the assumptions concerning an "ideal type" of social stratification in which the salient dimensions of intergroup differentiation are those involving scarce resources. more

Topics: Common ingroup identity (67%), Social identity theory (62%), In-group favoritism (62%) more

13,903 Citations

Open accessBook
Nello Cristianini1, John Shawe-Taylor2Institutions (2)
01 Jan 2000-
Abstract: From the publisher: This is the first comprehensive introduction to Support Vector Machines (SVMs), a new generation learning system based on recent advances in statistical learning theory. SVMs deliver state-of-the-art performance in real-world applications such as text categorisation, hand-written character recognition, image classification, biosequences analysis, etc., and are now established as one of the standard tools for machine learning and data mining. Students will find the book both stimulating and accessible, while practitioners will be guided smoothly through the material required for a good grasp of the theory and its applications. The concepts are introduced gradually in accessible and self-contained stages, while the presentation is rigorous and thorough. Pointers to relevant literature and web sites containing software ensure that it forms an ideal starting point for further study. Equally, the book and its associated web site will guide practitioners to updated literature, new applications, and on-line software. more

13,269 Citations

No. of papers from the Institution in previous years

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Institution's top 5 most impactful journals


1K papers, 130.4K citations


1K papers, 4.8K citations


840 papers, 40.5K citations

Physical Review Letters

834 papers, 58.9K citations

Social Science Research Network

772 papers, 16.7K citations

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