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Institution

University of British Columbia

EducationVancouver, British Columbia, Canada
About: University of British Columbia is a education organization based out in Vancouver, British Columbia, Canada. It is known for research contribution in the topics: Population & Poison control. The organization has 89939 authors who have published 209679 publications receiving 9226862 citations. The organization is also known as: UBC & The University of British Columbia.


Papers
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Journal ArticleDOI
TL;DR: This article used repeat photography, long-term ecological monitoring and dendrochronology to document shrub expansion in arctic, high-latitude and alpine tundra.
Abstract: Recent research using repeat photography, long-term ecological monitoring and dendrochronology has documented shrub expansion in arctic, high-latitude and alpine tundra

1,153 citations

Journal ArticleDOI
TL;DR: In this article, the authors hypothesize that independent institutions with long-term investments specialize in monitoring and influencing efforts rather than trading and show that only concentrated holdings by independent longterm institutions are related to post-merger performance.

1,152 citations

Journal ArticleDOI
TL;DR: This paper found negative correlations between maximizing and happiness, optimism, self-esteem, and life satisfaction, and positive correlations between maximization and depression, perfectionism, and regret, and found that maximizers are less satisfied than non-maximizers with consumer decisions, and more likely to engage in social comparison.
Abstract: Can people feel worse off as the options they face increase? The present studies suggest that some people--maximizers--can. Study 1 reported a Maximization Scale, which measures individual differences in desire to maximize. Seven samples revealed negative correlations between maximization and happiness, optimism, self-esteem, and life satisfaction, and positive correlations between maximization and depression, perfectionism, and regret. Study 2 found maximizers less satisfied than nonmaximizers (satisficers) with consumer decisions, and more likely to engage in social comparison. Study 3 found maximizers more adversely affected by upward social comparison. Study 4 found maximizers more sensitive to regret and less satisfied in an ultimatum bargaining game. The interaction between maximizing and choice is discussed in terms of regret, adaptation, and self-blame.

1,151 citations

Journal ArticleDOI
01 Jul 1998-JAMA
TL;DR: New data have provided a stronger rationale for earlier initiation of more aggressive therapy than previously recommended and reinforce the importance of careful selection of initial drug regimen for each patient for optimal long-term clinical benefit and adherence.
Abstract: Objective.—To provide recommendations for antiretroviral therapy based on information available in mid-1998.Participants.—An international panel of physicians with expertise in antiretroviral research and care of patients with human immunodeficiency virus (HIV) infection, first convened by the International AIDS Society–USA in December 1995.Evidence.—The panel reviewed available clinical and basic science study results (including phase 3 controlled trials; clinical, virologic, and immunologic end point data; data presented at research conferences; and studies of HIV pathophysiology); opinions of panel members were also considered. Recommendations were limited to drugs available in mid-1998.Consensus Process.—Panel members monitor new clinical research reports and interim results. The full panel meets regularly to discuss how the new information may change treatment recommendations. Updated recommendations are developed through consensus of the entire panel at each stage of development.Conclusions.—Accumulating data from clinical and pathogenesis studies continue to support early institution of potent antiretroviral therapy in patients with HIV infection. A variety of combination regimens show potency, expanding choices for initial regimens for individual patients. Plasma HIV RNA assays with increased sensitivity are important in monitoring therapeutic response; however, more data are needed to determine precisely the HIV RNA levels that define treatment failure. Long-term adverse drug effects are beginning to emerge, requiring ongoing attention. Some issues regarding optimal long-term approaches to antiretroviral management are unresolved. The increased complexity in HIV management requires ongoing monitoring of new data for optimal treatment of HIV infection.

1,151 citations

Journal ArticleDOI
TL;DR: The technology needed to diagnose and quantitate the individual small airway and emphysema phenotypes present in people with COPD is being developed, and should prove helpful in the assessment of therapeutic interventions designed to modify the progress of either phenotype.

1,150 citations


Authors

Showing all 90682 results

NameH-indexPapersCitations
Gordon H. Guyatt2311620228631
John C. Morris1831441168413
Douglas Scott1781111185229
John R. Yates1771036129029
Deborah J. Cook173907148928
Richard A. Gibbs172889249708
Evan E. Eichler170567150409
James F. Sallis169825144836
Michael Snyder169840130225
Jiawei Han1681233143427
Michael Kramer1671713127224
Bruce L. Miller1631153115975
Peter A. R. Ade1621387138051
Marc W. Kirschner162457102145
Kaj Blennow1601845116237
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023307
20221,209
202113,228
202012,052
201910,934