scispace - formally typeset
Search or ask a question
Institution

University of Cagliari

EducationCagliari, Italy
About: University of Cagliari is a education organization based out in Cagliari, Italy. It is known for research contribution in the topics: Population & Dopamine. The organization has 11029 authors who have published 29046 publications receiving 771023 citations. The organization is also known as: Università degli Studi di Cagliari & Universita degli Studi di Cagliari.


Papers
More filters
Journal ArticleDOI
TL;DR: This paper examines a few characteristics of iron chelators, with some emphasis on the effects of redox cycling, on absorption mechanisms and on some properties of the pFe.

147 citations

Journal ArticleDOI
TL;DR: A nonredundant role of VGF products in the regulation of energy storage and expenditure is implied, implying a non redundant roles in theregulation of energystorage and expenditure.
Abstract: 1. The vgf gene encodes a neuropeptide precursor with a restricted pattern of expression that is limited to a subset of neurons in the central and peripheral nervous systems and to specific populations of endocrine cells in the adenohypophysis, adrenal medulla, gastrointestinal tract, and pancreas. In responsive neurons, vgf transcription is upregulated by neurotrophins, the basis for the original identification of VGF as nerve growth factor- (NGF) inducible in PC12 cells (A. Levi, J. D. Eldridge, and B. M. Paterson, Science229:393–395, 1985).

147 citations

Journal ArticleDOI
TL;DR: It is shown that capsinoids also show remarkable antioxidant activity, and benign analogues of capsaicin could protect linoleic acid against free radical attack in simple in vitro systems, inhibiting both its autoxidation and its iron- or EDTA-mediated oxidation.
Abstract: Hot peppers are a good source of dietary antioxidants, encompassing, apart from widespread compounds (flavonoids, phenolic acids, carotenoids, vitamin A, ascorbic acid, tocopherols), also specific constituents such as the pungent capsaicinoids (capsaicin, dihydrocapsaicin, and related analogues). We have shown that capsinoids also show remarkable antioxidant activity. These benign analogues of capsaicin could protect linoleic acid against free radical attack in simple in vitro systems, inhibiting both its autoxidation and its iron- or EDTA-mediated oxidation. These properties were retained in some simple synthetic analogues (vanillyl nonanoate and its dimerization products). Capsiate, dihydrocapsiate, and their analogues were devoid of pro-oxidant activity and showed a highly significant antioxidant activity in all systems investigated. Vanillyl nonanoate, a simple capsinoid mimic, was also tested on cell cultures for cytotoxic activity and the capacity to inhibit FeCl(3)-induced oxidation.

147 citations

Journal ArticleDOI
TL;DR: It is found that a time-dependent regulation is effective for the sole A transport system (affecting the maximal velocity without substantial changes in K m ) and a comprehensive explanation for previously reported changes with time and intracellular substrate concentration of the kinetic parameters governing the uptake of the analogue.

146 citations


Authors

Showing all 11160 results

NameH-indexPapersCitations
Herbert W. Marsh15264689512
Michele Parrinello13363794674
Dafna D. Gladman129103675273
Peter J. Anderson12096663635
Alessandro Vespignani11841963824
C. Patrignani1171754110008
Hermine Katharina Wöhri11662955540
Francesco Muntoni11596352629
Giancarlo Comi10996154270
Giorgio Parisi10894160746
Luca Benini101145347862
Alessandro Cardini101128853804
Nicola Serra100104246640
Jurg Keller9938935628
Giulio Usai9751739392
Network Information
Related Institutions (5)
University of Florence
79.5K papers, 2.3M citations

97% related

Sapienza University of Rome
155.4K papers, 4.3M citations

97% related

University of Bologna
115.1K papers, 3.4M citations

96% related

University of Padua
114.8K papers, 3.6M citations

96% related

University of Milan
139.7K papers, 4.6M citations

96% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202374
2022230
20211,898
20201,903
20191,636
20181,600