scispace - formally typeset
Search or ask a question
Institution

University of California

EducationOakland, California, United States
About: University of California is a education organization based out in Oakland, California, United States. It is known for research contribution in the topics: Population & Layer (electronics). The organization has 55175 authors who have published 52933 publications receiving 1491169 citations. The organization is also known as: UC & University of California System.


Papers
More filters
Journal Article
TL;DR: The study of the forces acting in and around the hip joint explains numerous, apparently unrelated, clinical observations.
Abstract: The study of the forces acting in and around the hip joint explains numerous, apparently unrelated, clinical observations. The reacting force in the head of the femur resists not merely the pressure of the superincumbent body weight, but, in addition, the force of the abductor muscles and the tension on the iliotibial tract which is necessary to hold the pelvis in equilibrium. This latter force exceeds the weight of the body by a ratio of from 1.4:1 to 1.9:1. The minimum static pressure on the head of the femur is approximately 2.4 to 2.6 times the body weight. Normally this force is not borne vertically, but at an angle of approximately 165 to 170 degrees from the vertical and in line with the medial trabeculae of the femoral neck. This static force remains constant in direction, irrespective of whether the pelvis is levated or depressed on the non-weight-bearing side. With the knowledge of the direction of the reacting force through the head and neck of the femur against the pelvis, the changing angle of the capital epiphysis during growth becomes partially explicable. Close inspection of roentgenograms of the upper end of the femur in individuals of various ages reveals that the epiphyseal line always lies at a right angle to the direction of the medial trabeculae of the femoral neck (Fig.9). Since the reacting force in the femur follows these trabeculae, there is no sheer on the epiphyseal cartilage. The only force to which it is subjected normally is a compressional one. As growth occurs, with increasing length of the femoral neck and increasing angle of pull of the abductor muscles and the fascia, the epiphyseal cartilaginous plate rotates so as to lie perpendicular to the equilibrant force in the femoral neck. The interrelationship of these forces becomes altered in cases of paralysis of the abductor muscles and in congenital dislocation of the hip. In the first instance, the loss of muscle power prevents the attainment of equilibrium with the body in a normal position. To prevent the pelvis from rotating toward the non-weight-bearing side, the individual shifts his center of gravity over the affected hip by bending to that side. The resultant forces, acting through the hip, become more nearly vertical. The equilibrant or reacting force in the femoral neck likewise shifts toward the vertical; the epiphyseal cartilaginous plate, remaining perpendicular to these forces, continues to be relatively horizontal; and coxa valga results. This is a constant finding in individuals who have had paralysis early in life, and the degree of coxa valga is in proportion to the loss of muscle power. Coxa valga occurs in individuals suffering from congenital dislocation of the hip, for the same factors are at work. In these cases, the loss of fulcrum prevents the normal development of the abducting forces. The load is borne vertically on the femur, and the capital epiphysis reacts by remaining horizontal. [see pdf for figure] The so-called "antalgic" gait of the individual who has a painful disease of the hip joint is of interest. On the surface,it appears rather peculiar that a patient with a painful hip will walk by throwing himself over the painful joint, giving rise to a gait which may be compared with that of a glutaeus medius weakness. By so doing, however, the individual shifts his center of gravity over the hip, thus decreasing the required pull of the abductor muscles. This, in turn, decreases the pressure upon the femoral head from a force of 2.4 to 2.6 times the body weight to simply the superincumbent body weight. This expediency of gait, while decreasing the total load on the femoral head, results in a change in the direction of the reacting force in the femur. Instead of the body weight being borne at an angle which thrusts the head into the acetabulum, the load is carried vertically upon the femur. This alteration in direction of the forces causes changes in the femoral head, which are depicted in the roentgenograms. In malum coxae senilis, the bone changes affect predominantly the superior aspect of the femoral head, because the forces are concentrated there. In epiphysiolysis the assumption of an antalgic gait, while leading to a decrease in the total load on the femur, causes that load to be borne vertically, with the result that a sheer is applied to the epiphyseal plate, which normally is not present. This sheer will facilitate further slipping. The importance of the abductor muscles and the iliotibial tract in altering the direction of the reacting forces in the femoral neck should be emphasized. Any surgical approach to the hip joint which injures these structures and weakens the forces exerted by them will not only modify the magnitude, but also the direction, of the reacting force through the femoral neck.

279 citations

Book ChapterDOI
21 Aug 2000
TL;DR: This paper focuses on integrity critical databases, such as financial data used in high-value decisions, which are frequently published over the Internet and must satisfy the integrity, authenticity, and non-repudiation requirements of clients.
Abstract: Integrity critical databases, such as financial data used in high-value decisions, are frequently published over the Internet. Publishers of such data must satisfy the integrity, authenticity, and non-repudiation requirements of clients. Providing this protection over public networks is costly.

279 citations

Journal ArticleDOI
01 Jan 2005
TL;DR: In this article, the authors assess accomplishments of theory in combustion over the past fifty years and prospects for the future and emphasize that development of theory necessarily goes hand-in-hand with specification of a model.
Abstract: In honor of the fiftieth anniversary of the Combustion Institute, we are asked to assess accomplishments of theory in combustion over the past fifty years and prospects for the future. The title of our article is chosen to emphasize that development of theory necessarily goes hand-in-hand with specification of a model. Good conceptual models underlie successful mathematical theories. Models and theories are discussed here for deflagrations, detonations, diffusion flames, ignition, propellant combustion, and turbulent combustion. In many of these areas, the genesis of mathematical theories occurred during the past fifty years, and in all of them significant advances are anticipated in the future. Increasing interaction between theory and computation will aid this progress. We hope that, although certainly not complete in topical coverage or reference citation, the presentation may suggest useful directions for future research in combustion theory.

279 citations

Journal Article
01 Jan 1999-Daedalus
TL;DR: The author argues that most people who sell their organs in India do so in order to pay already existing debts, and the transaction is only temporarily an exchange of life for life, and most donors are back in debt soon after the operation.
Abstract: This article focuses on ethical issues surrounding the selling and buying of human organs. The author argues that most people who sell their organs (mainly kidneys) in India do so in order to pay already existing debts. The transaction is only temporarily an exchange of life for life, and most donors are back in debt soon after the operation. The author discusses the flexible ethics that reduce reality to dyadic transactions and the purgatorial ethics that collapse real and imaginary exploitation in the service of complex interests. He also offers a sophisticated discussion of the ethics of publicity and public ethics. He emphasizes the lack of factual information, intentional manipulation of information, and the dissemination of kidney panics and kidney scandals, especially by the new developing bioauthorities and bioethical brokers.

279 citations

Journal ArticleDOI
TL;DR: In this article, the authors used a survey to quantify variability in the perception of the vulnerability of permafrost C to climate change and found that approximately 1700 Pg of soil carbon (C) are stored in the northern circumpolar permafure zone, more than twice as much C than in the atmosphere.
Abstract: Approximately 1700 Pg of soil carbon (C) are stored in the northern circumpolar permafrost zone, more than twice as much C than in the atmosphere. The overall amount, rate, and form of C released to the atmosphere in a warmer world will influence the strength of the permafrost C feedback to climate change. We used a survey to quantify variability in the perception of the vulnerability of permafrost C to climate change. Experts were asked to provide quantitative estimates of permafrost change in response to four scenarios of warming. For the highest warming scenario (RCP 8.5), experts hypothesized that C release from permafrost zone soils could be 19–45 Pg C by 2040, 162–288 Pg C by 2100, and 381–616 Pg C by 2300 in CO2 equivalent using 100-year CH4 global warming potential (GWP). These values become 50 % larger using 20-year CH4 GWP, with a third to a half of expected climate forcing coming from CH4 even though CH4 was only 2.3 % of the expected C release. Experts projected that two-thirds of this release could be avoided under the lowest warming scenario (RCP 2.6). These results highlight the potential risk from permafrost thaw and serve to frame a hypothesis about the magnitude of this feedback to climate change. However, the level of emissions proposed here are unlikely to overshadow the impact of fossil fuel burning, which will continue to be the main source of C emissions and climate forcing.

278 citations


Authors

Showing all 55232 results

NameH-indexPapersCitations
Meir J. Stampfer2771414283776
George M. Whitesides2401739269833
Michael Karin236704226485
Fred H. Gage216967185732
Rob Knight2011061253207
Martin White1962038232387
Simon D. M. White189795231645
Scott M. Grundy187841231821
Peidong Yang183562144351
Patrick O. Brown183755200985
Michael G. Rosenfeld178504107707
George M. Church172900120514
David Haussler172488224960
Yang Yang1712644153049
Alan J. Heeger171913147492
Network Information
Related Institutions (5)
Cornell University
235.5K papers, 12.2M citations

95% related

University of California, Berkeley
265.6K papers, 16.8M citations

94% related

University of Minnesota
257.9K papers, 11.9M citations

94% related

University of Wisconsin-Madison
237.5K papers, 11.8M citations

94% related

Stanford University
320.3K papers, 21.8M citations

93% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202322
2022105
2021775
20201,069
20191,225
20181,684