University of California

About: University of California is a education organization based out in Oakland, California, United States. It is known for research contribution in the topics: Population & Layer (electronics). The organization has 55175 authors who have published 52933 publications receiving 1491169 citations. The organization is also known as: UC & University of California System.

Response of microbial community composition and function to soil climate change.

Abstract: Soil microbial communities mediate critical ecosystem carbon and nutrient cycles. How microbial communities will respond to changes in vegetation and climate, however, are not well understood. We reciprocally transplanted soil cores from under oak canopies and adjacent open grasslands in a California oak-grassland ecosystem to determine how microbial communities respond to changes in the soil environment and the potential consequences for the cycling of carbon. Every 3 months for up to 2 years, we monitored microbial community composition using phospholipid fatty acid analysis (PLFA), microbial biomass, respiration rates, microbial enzyme activities, and the activity of microbial groups by quantifying (13)C uptake from a universal substrate (pyruvate) into PLFA biomarkers. Soil in the open grassland experienced higher maximum temperatures and lower soil water content than soil under the oak canopies. Soil microbial communities in soil under oak canopies were more sensitive to environmental change than those in adjacent soil from the open grassland. Oak canopy soil communities changed rapidly when cores were transplanted into the open grassland soil environment, but grassland soil communities did not change when transplanted into the oak canopy environment. Similarly, microbial biomass, enzyme activities, and microbial respiration decreased when microbial communities were transplanted from the oak canopy soils to the grassland environment, but not when the grassland communities were transplanted to the oak canopy environment. These data support the hypothesis that microbial community composition and function is altered when microbes are exposed to new extremes in environmental conditions; that is, environmental conditions outside of their "life history" envelopes.

Decidual Stromal Cell Response to Paracrine Signals from the Trophoblast: Amplification of Immune and Angiogenic Modulators

Abstract: During the invasive phase of implantation, trophoblasts and maternal decidual stromal cells secrete products that regulate trophoblast differentiation and migration into the maternal endometrium. Paracrine interactions between the extravillous trophoblast and the maternal decidua are important for successful embryonic implantation, including establishing the placental vasculature, anchoring the placenta to the uterine wall, and promoting the immunoacceptance of the fetal allograph. To our knowledge, global crosstalk between the trophoblast and the decidua has not been elucidated to date, and the present study used a functional genomics approach to investigate these paracrine interactions. Human endometrial stromal cells were decidualized with progesterone and further treated with conditioned media from human trophoblasts (TCM) or, as a control, with control conditioned media (CCM) from nondecidualized stromal cells for 0, 3, and 12 h. Total RNA was isolated and processed for analysis on whole-genome, high-density oligonucleotide arrays containing 54,600 genes. We found that 1374 genes were significantly upregulated and that 3443 genes were significantly downregulated after 12 h of coincubation of stromal cells with TCM, compared to CCM. Among the most upregulated genes were the chemokines CXCL1 (GRO1) and IL8,CXCR4, and other genes involved in the immune response (CCL8 [SCYA8], pentraxin 3 (PTX3), IL6, and interferon-regulated and -related genes) as well as TNFAIP6 (tumor necrosis factor alpha-induced protein 6) and metalloproteinases (MMP1, MMP10, and MMP14). Among the downregulated genes were growth factors, e.g., IGF1, FGF1, TGFB1, and angiopoietin-1, and genes involved in Wnt signaling (WNT4 and FZD). Real-time RT-PCR and ELISAs, as well as immunohistochemical analysis of human placental bed specimens, confirmed these data for representative genes of both up- and downregulated groups. The data demonstrate a significant induction of proinflammatory cytokines and chemokines, as well as angiogenic/static factors in decidualized endometrial stromal cells in response to trophoblast-secreted products. The data suggest that the trophoblast acts to alter the local immune environment of the decidua to facilitate the process of implantation and ensure an enriched cytokine/chemokine environment while limiting the mitotic activity of the stromal cells during the invasive phase of implantation.

Singularities in the physical region

Abstract: It is shown that a Feynman amplitude has singularities on the physical boundary if and only if the relevant Feynman diagram can be interpreted as a picture of an energy- and momentum-conserving process occurring in space-time, with all internal particles real, on the mass shell, and moving forward in time. As a by-product of the proof, the Feynman parameter associated with an internal line is identified (within a proportionality factor) with the time the particle exists between collisions, divided by its mass.

Reconceptualizing ‘flaming’ and other problematic messages

Abstract: Researchers examining ‘flaming’ - defined as hostile and aggressive interactions via text-based computer mediated-communication - have proposed theoretical frameworks to explain possible causes. However, precise conceptual and operational definitions of ‘flaming’ have yet to be established, which has implications for understanding this phenomenon. Consequently, we propose an interactional- normative framework that focuses on interpretations of messages from multiple perspectives in the situated and evolving context of appropriateness norms. This framework incorporates intentionality and individuals’ strategic choices in language use and channel selection. We discuss the implications of this framework for research on flaming and other problematic interactions.

The nature of the black–white difference on various psychometric tests: Spearman's hypothesis

Abstract: Although the black and white populations in the United States differ, on average, by about one standard deviation (equivalent to 15 IQ points) on current IQ tests, they differ by various amounts on different tests. The present study examines the nature of the highly variable black–white difference across diverse tests and indicates the major systematic source of this between-population variation, namely, Spearman's g. Charles Spearman originally suggested in 1927 that the varying magnitude of the mean difference between black and white populations on a variety of mental tests is directly related to the size of the test's loading on g, the general factor common to all complex tests of mental ability. Eleven large-scale studies, each comprising anywhere from 6 to 13 diverse tests, show a significant and substantial correlation between tests' g loadings and the mean black–white difference (expressed in standard score units) on the various tests. Hence, in accord with Spearman's hypothesis, the average black–white difference on diverse mental tests may be interpreted as chiefly a difference in g, rather than as a difference in the more specific sources of test score variance associated with any particular informational content, scholastic knowledge, specific acquired skill, or type of test. The results of recent chronometric studies of relatively simple cognitive tasks suggest that the g factor is related, at least in part, to the speed and efficiency of certain basic information-processing capacities. The consistent relationship of these processing variables to g and to Spearman's hypothesis suggests the hypothesis that the differences between black and white populations in the rate of information processing may account for a part of the average black–white difference on standard IQ tests and their educational and occupational correlates.