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Institution

University of California, Santa Cruz

EducationSanta Cruz, California, United States
About: University of California, Santa Cruz is a education organization based out in Santa Cruz, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 15541 authors who have published 44120 publications receiving 2759983 citations. The organization is also known as: UCSC & UC, Santa Cruz.
Topics: Galaxy, Population, Star formation, Redshift, Planet


Papers
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Journal ArticleDOI
28 Jul 2006-Cell
TL;DR: The full-length hammerhead structure reveals how tertiary interactions occurring remotely from the active site prime this ribozyme for catalysis and permits us to explain the previously irreconcilable sets of experimental results in a unified, consistent, and unambiguous manner.

458 citations

Proceedings Article
06 Aug 1999
TL;DR: A new method, called the Fisher kernel method, for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily.
Abstract: A new method, called the Fisher kernel method, for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support vector machines using a new kernel function. The kernel function is derived from a hidden Markov model. The general approach of combining generative models like HMMs with discriminative methods such as support vector machines may have applications in other areas of biosequence analysis as well.

457 citations

Journal ArticleDOI
28 Jun 1996-Science
TL;DR: Pore fluids from the upper 60 meters of sediment 3000 meters below the surface of the tropical Atlantic indicate that the oxygen isotopic composition of seawater at this site during the last glacial maximum was 0.8 ± 0.1 per mil higher than it is today.
Abstract: Pore fluids from the upper 60 meters of sediment 3000 meters below the surface of the tropical Atlantic indicate that the oxygen isotopic composition (δ 18 O) of seawater at this site during the last glacial maximum was 0.8 ± 0.1 per mil higher than it is today. Combined with the δ 18 O change in benthic foraminifera from this region, the elevated ratio indicates that the temperature of deep water in the tropical Atlantic Ocean was 4°C colder during the last glacial maximum. Extrapolation from this site to a global average suggests that the ice volume contribution to the change in δ 18 O of foraminifera is 1.0 per mil, which partially reconciles the foraminiferal oxygen isotope record of tropical sea surface temperatures with estimates from Barbados corals and terrestrial climate proxies.

456 citations

Proceedings ArticleDOI
31 Oct 2008
TL;DR: This work has developed a solution that provides both data security and space efficiency in single-server storage and distributed storage systems.
Abstract: As the world moves to digital storage for archival purposes, there is an increasing demand for systems that can provide secure data storage in a cost-effective manner. By identifying common chunks of data both within and between files and storing them only once, deduplication can yield cost savings by increasing the utility of a given amount of storage. Unfortunately, deduplication exploits identical content, while encryption attempts to make all content appear random; the same content encrypted with two different keys results in very different ciphertext. Thus, combining the space efficiency of deduplication with the secrecy aspects of encryption is problematic.We have developed a solution that provides both data security and space efficiency in single-server storage and distributed storage systems. Encryption keys are generated in a consistent manner from the chunk data; thus, identical chunks will always encrypt to the same ciphertext. Furthermore, the keys cannot be deduced from the encrypted chunk data. Since the information each user needs to access and decrypt the chunks that make up a file is encrypted using a key known only to the user, even a full compromise of the system cannot reveal which chunks are used by which users.

456 citations

Journal ArticleDOI
19 May 1989-Cell
TL;DR: EF-Tu prevents interaction of the 3' terminus of the incoming aminoacyl-tRNA with the peptidyl transferase region of the ribosome during anticodon selection, thereby permitting translational proofreading.

456 citations


Authors

Showing all 15733 results

NameH-indexPapersCitations
David J. Schlegel193600193972
David R. Williams1782034138789
John R. Yates1771036129029
David Haussler172488224960
Evan E. Eichler170567150409
Anton M. Koekemoer1681127106796
Mark Gerstein168751149578
Alexander S. Szalay166936145745
Charles M. Lieber165521132811
Jorge E. Cortes1632784124154
M. Razzano155515106357
Lars Hernquist14859888554
Aaron Dominguez1471968113224
Taeghwan Hyeon13956375814
Garth D. Illingworth13750561793
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202351
2022328
20212,157
20202,353
20192,209
20182,157