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Institution

University of California, Santa Cruz

EducationSanta Cruz, California, United States
About: University of California, Santa Cruz is a education organization based out in Santa Cruz, California, United States. It is known for research contribution in the topics: Galaxy & Population. The organization has 15541 authors who have published 44120 publications receiving 2759983 citations. The organization is also known as: UCSC & UC, Santa Cruz.
Topics: Galaxy, Population, Star formation, Redshift, Planet


Papers
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Journal ArticleDOI
TL;DR: This DNA transformation competent genomic library should expedite gene isolation, by gene rescue, in multicel–lular organisms like Arabidopsis, as with the unicellular organisms Escherichia coli and Saccharomyces cerevisiae.
Abstract: We have constructed a nuclear genomic library from the cruciferous plant Arabidopsis thaliana ecotype Columbia in a cosmid vector, pLZO3, and a host organism, Agrobacterium tumefaciens AGL1, which can directly DNA-transform the parent organism, Arabidopsis. The broad host range cosmid pLZO3 carries a gentamicin acetyltransferase gene as bacterial selective marker and tandem, chimeric neomycin and streptomycin phosphotransferase genes as plant selective markers. Agrobacterium AGL1 carries the hypervirulent, attenuated tumor-inducing plasmid pTiBo542 from which T-region DNA sequences have been precisely deleted, allowing optimal DNA transformation of many dicotyledonous plants. Agrobacterium AGL1 also carries an insertion mutation in its recA general recombination gene, which stabilizes the recombinant plasmids. The Arabidopsis genomic library consists of some 21,600 clones gridded onto 96-well microtiter dishes and, if random, carries at least three genomic equivalents. When probed for the presence of several Arabidopsis low copy-number genes, the genomic library seems representative. As with the unicellular organisms Escherichia coli and Saccharomyces cerevisiae, this DNA transformation competent genomic library should expedite gene isolation, by gene rescue, in multicellular organisms like Arabidopsis.

1,031 citations

Journal ArticleDOI
20 May 2005-Science
TL;DR: Tsunami and geodetic observations indicate that additional slow slip occurred in the north over a time scale of 50 minutes or longer, and fault slip of up to 15 meters occurred near Banda Aceh, Sumatra, but to the north, along the Nicobar and Andaman Islands, rapid slip was much smaller.
Abstract: The two largest earthquakes of the past 40 years ruptured a 1600-kilometer-long portion of the fault boundary between the Indo-Australian and southeastern Eurasian plates on 26 December 2004 [seismic moment magnitude (Mw) = 9.1 to 9.3] and 28 March 2005 (Mw = 8.6). The first event generated a tsunami that caused more than 283,000 deaths. Fault slip of up to 15 meters occurred near Banda Aceh, Sumatra, but to the north, along the Nicobar and Andaman Islands, rapid slip was much smaller. Tsunami and geodetic observations indicate that additional slow slip occurred in the north over a time scale of 50 minutes or longer.

1,030 citations

Journal ArticleDOI
TL;DR: A model for the fibrillation of α-synuclein is proposed in which the first step is the conformational transformation of the natively unfolded protein into the aggregation-competent partially folded intermediate.

1,028 citations

Journal ArticleDOI
08 Feb 1996-Nature
TL;DR: The topography of tectonically active mountain ranges reflects a poorly understood competition between bedrock uplift and erosion as mentioned in this paper, and the Indus river incises through the bedrock at extremely high rates (2-12 mm yr-1).
Abstract: The topography of tectonically active mountain ranges reflects a poorly understood competition between bedrock uplift and erosion. Dating of abandoned river-cut surfaces in the northwestern Himalayas reveals that the Indus river incises through the bedrock at extremely high rates (2–12 mm yr-1). In the surrounding mountains, the average angles of hillslopes are steep and essentially independent of erosion rate, suggesting control by a common threshold process. In this rapidly deforming region, an equilibrium is maintained between bedrock uplift and river incision, with landsliding allowing hillslopes to adjust efficiently to rapid river down-cutting.

1,027 citations

Journal ArticleDOI
01 Jun 1977-Nature
TL;DR: In this article, a history of geodynamic evolution of the Mediterranean leading to the salinity crisis is outlined, based on the 'desiccated deep-basin model' and an accurate portrayal of the crisis is presented.
Abstract: A history of geodynamic evolution of the Mediterranean leading to the salinity crisis is outlined, based on the ‘desiccated deep-basin model’. An accurate portrayal of the crisis is presented, based on data from new drilling and studies of on-land geology.

1,026 citations


Authors

Showing all 15733 results

NameH-indexPapersCitations
David J. Schlegel193600193972
David R. Williams1782034138789
John R. Yates1771036129029
David Haussler172488224960
Evan E. Eichler170567150409
Anton M. Koekemoer1681127106796
Mark Gerstein168751149578
Alexander S. Szalay166936145745
Charles M. Lieber165521132811
Jorge E. Cortes1632784124154
M. Razzano155515106357
Lars Hernquist14859888554
Aaron Dominguez1471968113224
Taeghwan Hyeon13956375814
Garth D. Illingworth13750561793
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202351
2022328
20212,157
20202,353
20192,209
20182,157