scispace - formally typeset
Search or ask a question
Institution

University of Coimbra

EducationCoimbra, Portugal
About: University of Coimbra is a education organization based out in Coimbra, Portugal. It is known for research contribution in the topics: Population & Context (language use). The organization has 14318 authors who have published 43067 publications receiving 994733 citations. The organization is also known as: UC & Universidade dos Estudos Gerais.


Papers
More filters
Journal ArticleDOI
TL;DR: The potential disease-modifying agents tested in clinical trials are discussed, the information of drugs that are still under clinical evaluation is updated and updated and the tau-targeting therapies are discussed.

224 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, S. Abdel Khalek4  +2881 moreInstitutions (168)
TL;DR: In this paper, two different analysis strategies based on monojetlike and c-tagged event selections are carried out to optimize the sensitivity for direct top-squark-pair production in the decay channel to a charm quark and the lightest neutralino.
Abstract: Results of a search for supersymmetry via direct production of third-generation squarks are reported, using 20.3 fb(-1) of proton-proton collision data at root s = 8 TeV recorded by the ATLAS experiment at the LHC in 2012. Two different analysis strategies based on monojetlike and c-tagged event selections are carried out to optimize the sensitivity for direct top squark-pair production in the decay channel to a charm quark and the lightest neutralino ((t) over tilde (1) -> c + (chi) over tilde (0)(1)) across the top squark-neutralino mass parameter space. No excess above the Standard Model background expectation is observed. The results are interpreted in the context of direct pair production of top squarks and presented in terms of exclusion limits in the (m((t) over tilde1), m((chi) over tilde 10)) parameter space. A top squark of mass up to about 240 GeV is excluded at 95% confidence level for arbitrary neutralino masses, within the kinematic boundaries. Top squark masses up to 270 GeV are excluded for a neutralino mass of 200 GeV. In a scenario where the top squark and the lightest neutralino are nearly degenerate in mass, top squark masses up to 260 GeV are excluded. The results from the monojetlike analysis are also interpreted in terms of compressed scenarios for top squark-pair production in the decay channel (t) over tilde (1) -> b + ff' + (chi) over tilde (0)(1) and sbottom pair production with (b) over tilde -> b + (chi) over tilde (0)(1), leading to a similar exclusion for nearly mass-degenerate third-generation squarks and the lightest neutralino. The results in this paper significantly extend previous results at colliders.

224 citations

Journal ArticleDOI
TL;DR: Fears of compassion for self, from others and in particular fear of happiness, were highly linked to different aspects of alexithymia, mindfulness, empathy, self-criticism and depression, anxiety and stress.
Abstract: Background. There is increasing research to suggest that fears of, and resistances to, affiliative and positive emotions are linked to self-criticism and a range of psychopathologies. It is unclear how these fears and resistances are linked to each other and how these in turn are linked to psychological processes, such as abilities to be mindful and recognize and describe emotions. Objectives. This research explores the relationship between fears of compassion and happiness in general, with capacities for emotional processing (alexithymia), capacities for mindfulness, and empathic abilities. To advance this research, a new scale was developed to measure general fears of positive feelings – the Fear of Happiness Scale. Results. The results showed that fears of compassion for self, from others and in particular fear of happiness, were highly linked to different aspects of alexithymia, mindfulness, empathy, self-criticism and depression, anxiety and stress. Especially noteworthy was the very high correlation between fear of happiness and depression (r= .70). Conclusion. While the development of positive emotions, especially those linked to affiliation and connectedness are increasingly seen as important therapeutic targets, little research has focused on the blocks and fears to positive emotions. This study used newly developed fears of positive affect scales (e.g., compassion and happiness) to explore these aspects and found they were significantly linked to psychopathology variables self-criticism and difficulties such as alexithymia.

223 citations

Journal ArticleDOI
TL;DR: In a cohort of patients in whom airway pressures and tidal volume are limited, barotrauma is more likely in patients ventilated due to underlying lung disease (acute or chronic) and was also associated with a significant increased in the ICU length of stay and mortality.
Abstract: Objective To determine the incidence, risk factors, and outcome of barotrauma in a cohort of mechanically ventilated patients where limited tidal volumes and airway pressures were used.

223 citations

Journal ArticleDOI
TL;DR: It is observed that oligomeric Abeta1-42 depletes ER Ca(2+) levels leading to intracellular Ca( 2+) dyshomeostasis involving phospholipase C activation and in the presence of dantrolene, an inhibitor of ERCa(2+) release through ryanodine receptors, the oligomer-induced apoptosis was prevented demonstrating the involvement of ER Ca (2+) release.

223 citations


Authors

Showing all 14693 results

NameH-indexPapersCitations
P. Chang1702154151783
Yang Gao1682047146301
Bin Liu138218187085
P. Sinervo138151699215
Filipe Veloso12888775496
Panagiotis Kokkas128123481051
Nuno Filipe Castro12896076945
Robert Gardner128101577619
Francois Corriveau128102275729
Peter Krieger128117181368
João Carvalho126127877017
Helmut Wolters12685175721
Nicola Venturi12679669518
Sai-Juan Chen121121173991
Harinder Singh Bawa12079866120
Network Information
Related Institutions (5)
University of Antwerp
48.8K papers, 1.6M citations

92% related

University of Pisa
73.1K papers, 2.1M citations

91% related

Sapienza University of Rome
155.4K papers, 4.3M citations

91% related

University of Padua
114.8K papers, 3.6M citations

91% related

University of Münster
69K papers, 2.2M citations

91% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
2023112
2022530
20213,238
20203,193
20193,090