University of Coimbra

About: University of Coimbra is a education organization based out in Coimbra, Portugal. It is known for research contribution in the topics: Population & Context (language use). The organization has 14318 authors who have published 43067 publications receiving 994733 citations. The organization is also known as: UC & Universidade dos Estudos Gerais.

Three-dimensional biomaterials for the study of human pluripotent stem cells

Abstract: The self-renewal and differentiation of human pluripotent stem cells (hPSCs) have typically been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that 3D model systems may be needed in addition, as they mimic the natural 3D tissue organization more closely. We survey methods that have used 3D biomaterials for expansion of undifferentiated hPSCs, directed differentiation of hPSCs and transplantation of differentiated hPSCs in vivo.

Vision and inertial sensor cooperation using gravity as a vertical reference

Abstract: This paper explores the combination of inertial sensor data with vision. Visual and inertial sensing are two sensory modalities that can be explored to give robust solutions on image segmentation and recovery of 3D structure from images, increasing the capabilities of autonomous robots and enlarging the application potential of vision systems. In biological systems, the information provided by the vestibular system is fused at a very early processing stage with vision, playing a key role on the execution of visual movements such as gaze holding and tracking, and the visual cues aid the spatial orientation and body equilibrium. In this paper, we set a framework for using inertial sensor data in vision systems, and describe some results obtained. The unit sphere projection camera model is used, providing a simple model for inertial data integration. Using the vertical reference provided by the inertial sensors, the image horizon line can be determined. Using just one vanishing point and the vertical, we can recover the camera's focal distance and provide an external bearing for the system's navigation frame of reference. Knowing the geometry of a stereo rig and its pose from the inertial sensors, the collineations of level planes can be recovered, providing enough restrictions to segment and reconstruct vertical features and leveled planar patches.

Dysfunctional Sexual Beliefs as Vulnerability Factors for Sexual Dysfunction

Abstract: The differences on sexual beliefs presented by men and women with sexual dysfunction and their sexually functional counterparts were investigated. A total of 488 participants (160 females and 232 males without sexual problems and 47 females and 49 males with a DSM-IV diagnosis of sexual dysfunction) answered the Sexual Dysfunctional Beliefs Questionnaire. Findings showed that, although effects have only reached statistical significance for the female group, both dysfunctional men and women endorsed more sexual dysfunctional beliefs than functional. Women presented significantly more age related beliefs (after menopause women loose their sexual desire, as women age, the pleasure they get from sex decreases) and body image beliefs (women who are not physically attractive cannot be sexually satisfied). Additionally, sexually dysfunctional males presented higher scores (not statistically significant) on 'macho' belief (a real man has sexual intercourse very often) and the beliefs about women satisfaction (the quality of the erection is what most satisfies women). Overall, findings support the idea that sexual beliefs may play a role as vulnerability factors for sexual dysfunction.