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Institution

University of Colorado Boulder

EducationBoulder, Colorado, United States
About: University of Colorado Boulder is a education organization based out in Boulder, Colorado, United States. It is known for research contribution in the topics: Population & Galaxy. The organization has 48794 authors who have published 115151 publications receiving 5387328 citations. The organization is also known as: CU Boulder & UCB.
Topics: Population, Galaxy, Poison control, Solar wind, Stars


Papers
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Journal ArticleDOI
04 Jul 2008-Science
TL;DR: In this paper, a new data set of fossil occurrences representing 3.5 million specimens was presented, and it was shown that global and local diversity was less than twice as high in the Neogene as in the mid-Paleozoic.
Abstract: It has previously been thought that there was a steep Cretaceous and Cenozoic radiation of marine invertebrates. This pattern can be replicated with a new data set of fossil occurrences representing 3.5 million specimens, but only when older analytical protocols are used. Moreover, analyses that employ sampling standardization and more robust counting methods show a modest rise in diversity with no clear trend after the mid-Cretaceous. Globally, locally, and at both high and low latitudes, diversity was less than twice as high in the Neogene as in the mid-Paleozoic. The ratio of global to local richness has changed little, and a latitudinal diversity gradient was present in the early Paleozoic.

650 citations

Journal ArticleDOI
TL;DR: This manuscript discusses guiding principles for the workup, staging, and treatment of early stage and locally advanced cervical cancer, as well as evidence for these recommendations.
Abstract: Cervical cancer is a malignant epithelial tumor that forms in the uterine cervix. Most cases of cervical cancer are preventable through human papilloma virus (HPV) vaccination, routine screening, and treatment of precancerous lesions. However, due to inadequate screening protocols in many regions of the world, cervical cancer remains the fourth-most common cancer in women globally. The complete NCCN Guidelines for Cervical Cancer provide recommendations for the diagnosis, evaluation, and treatment of cervical cancer. This manuscript discusses guiding principles for the workup, staging, and treatment of early stage and locally advanced cervical cancer, as well as evidence for these recommendations. For recommendations regarding treatment of recurrent or metastatic disease, please see the full guidelines on NCCN.org.

649 citations

Journal ArticleDOI
TL;DR: In this paper, the authors present a tomographic model of 3D variations in mantle P wave velocity, parameterized by means of rectangular cells in latitude, longitude, and radius, the size of which adapts to sampling density by short-period (1 Hz) data.
Abstract: [1] We document our tomographic method and present a new global model of three-dimensional (3-D) variations in mantle P wave velocity. The model is parameterized by means of rectangular cells in latitude, longitude, and radius, the size of which adapts to sampling density by short-period (1 Hz) data. The largest single data source is ISC/NEIC data reprocessed by Engdahl and coworkers, from which we use routinely picked, short-period P, Pg, Pn, pP, and pwP data (for earthquakes during the period 1964∼2007). To improve the resolution in the lowermost and uppermost mantle, we use differential times of core phases (PKPAB − PKPDF, PKPAB − PKPBC, Pdiff − PKPDF) and surface-reflected waves (PP-P). The low-frequency differential times (Pdiff, PP) are measured by waveform cross correlation. Approximate 3-D finite frequency kernels are used to integrate the long-period data (Pdiff, PP) and short-period (P, pP, PKP) data. This global data set is augmented with data from regional catalogs and temporary seismic arrays. A crust correction is implemented to mitigate crustal smearing into the upper mantle. We invert the data for 3-D variations in P wave speed and effects of hypocenter mislocation subject to norm and gradient regularization. Spatial resolution is ∼100 km in the best sampled upper mantle regions. Our model, which is available online and which will be updated periodically, reveals in unprecedented detail the rich variation in style of subduction of lithospheric slabs into the mantle. The images confirm the structural complexity of downwellings in the transition zone discussed in previous papers and show with more clarity the structure of slab fragments stagnant in the transition zone beneath east Asia. They also reveal low wave speed beneath major hot spots, such as Iceland, Afar, and Hawaii, but details of these structures are not well resolved by the data used.

648 citations

Journal ArticleDOI
TL;DR: The authors explored the relationship between potential financial reward and opportunity identification and found that the less knowledgeable an individual was about customer problems, the more positive the effect that potential monetary reward had on the number of opportunities identified and the innovativeness of those opportunities.
Abstract: This article simultaneously explores the constructs of potential financial reward and prior knowledge of customer problems to provide a deeper understanding of the identification of opportunities. Results suggest that while prior knowledge of customer problems leads to the identification of more opportunities and opportunities that are more innovative, it also moderates the relationship between potential financial reward and opportunity identification. We found that the less knowledgeable an individual was about customer problems, the more positive the effect that potential financial reward had on the number of opportunities identified and the innovativeness of those opportunities.

648 citations

Journal ArticleDOI
TL;DR: This article summarizes a 27-year program of research that has attempted to improve early maternal and child health and future life options with prenatal and infancy home visiting by nurses for low-income mothers who have had no previous live births.
Abstract: Pregnancy and the early years of the child's life offer an opportune time to prevent a host of adverse maternal, child, and family outcomes that are important in their own right, but that also reflect biological, behavioral, and social substrates in the child and family that affect family formation and future life trajectories. This article summarizes a 27-year program of research that has attempted to improve early maternal and child health and future life options with prenatal and infancy home visiting by nurses. The program is designed for low-income mothers who have had no previous live births. The home-visiting nurses have three major goals: to improve the outcomes of pregnancy by helping women improve their prenatal health, to improve the child's health and development by helping parents provide more sensitive and competent care of the child, and to improve parental life course by helping parents plan future pregnancies, complete their education, and find work. The program has been tested in three separate large-scale, randomized controlled trials with different populations living in different contexts. Results from these trials indicate that the program has been successful in achieving two of its most important goals: (a) the improvement of parental care of the child as reflected in fewer injuries and ingestions that may be associated with child abuse and neglect and better infant emotional and language development; and (b) the improvement of maternal life course, reflected in fewer subsequent pregnancies, greater work-force participation, and reduced dependence on public assistance and food stamps. The impact on pregnancy outcomes is equivocal. In the first trial, the program also produced long-term effects on the number of arrests, convictions, emergent substance use, and promiscuous sexual activity of 15-year-old children whose nurse-visited mothers were low-income and unmarried when they registered in the study during pregnancy. In general, the impact of the program was greater on those segments of the population at greater risk for the particular outcome domain under examination. Since 1996, the program has been offered for public investment outside of research contexts. Careful attention has been given to ensuring that organizational and community contexts are favorable for development of the program, to providing excellent training and guidance to the nurses in their use of the program's visit-by-visit guidelines, to monitoring the functioning of the program with a comprehensive clinical information system, and to improving the performance of the programs over time with continuous improvement strategies.

648 citations


Authors

Showing all 49233 results

NameH-indexPapersCitations
Yi Chen2174342293080
Robert J. Lefkowitz214860147995
Rob Knight2011061253207
Charles A. Dinarello1901058139668
Jie Zhang1784857221720
David Haussler172488224960
Bradley Cox1692150156200
Gang Chen1673372149819
Rodney S. Ruoff164666194902
Menachem Elimelech15754795285
Jay Hauser1552145132683
Robert E. W. Hancock15277588481
Robert Plomin151110488588
Thomas E. Starzl150162591704
Rajesh Kumar1494439140830
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023164
2022779
20216,286
20206,493
20196,063
20185,522