University of Colorado Colorado Springs

About: University of Colorado Colorado Springs is a education organization based out in Colorado Springs, Colorado, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 6664 authors who have published 10872 publications receiving 323416 citations. The organization is also known as: UCCS & University of Colorado at Colorado Springs.

Endocardial lead removing apparatus

Abstract: The invention provides an apparatus having a tubular member for receiving an endocardia (1) lead implanted within a patient's body. Disposed generally at a distal end of the tubular member is at least one blade or cutting surface. An adjustment mechanism moves the blade between retracted and extended positions to engage the cutting surface with the endocardia (1) lead to cut the lead. Once severed, the cut portion of the lead remains within an inner channel of the tubular member and the apparatus and cut portion of the lead are removed from within the patient. Alternatively, in some embodiments, the cut portion of the lead is disposed externally to the tubular member, and the cut portion and the apparatus are removed from the patient, either separately or together. Various embodiments include the blade pivotally connected to the distal end of the tubular member and activated by a wire adjustment mechanism.

Terror management and adults' attachment to their parents: the safe haven remains.

Abstract: Six studies examined the role of young adults' parental attachment in terror management. Studies 1-3 revealed that activating thoughts of one's parent in response to mortality salience (MS) reduced death-thought accessibility and worldview defense and increased feelings of self-worth. Studies 4-5 demonstrated that MS led to greater ease of recalling positive maternal interactions and greater difficulty recalling negative interactions, and increased attraction to a stranger who was described as being similar to one's parent. If reliance on parents for terror management purposes reflects the operation of attachment mechanisms, then such effects should vary on the basis of an individual's attachment style. Study 6 demonstrated that, after MS, insecure individuals were more likely to rely on relationships with their parents, whereas secure individuals were more likely to rely on relationships with romantic partners.

A comparison of algorithms for the pairwise alignment of biological networks

Abstract: Motivation: As biological inquiry produces ever more network data, such as protein-protein interaction networks, gene regulatory networks, and metabolic networks, many algorithms have been proposed for the purpose of pairwise network alignment‐ finding a mapping from the nodes of one network to the nodes of another in such a way that the mapped nodes can be considered to correspond with respect to both their place in the network topology and their biological attributes. This technique is helpful in identifying previously undiscovered homologies between proteins of different species and revealing functionally similar subnetworks. In the past few years, a wealth of different aligners have been published, but few of them have been compared to one another, and no comprehensive review of these algorithms has yet appeared. Results: We present the problem of biological network alignment, provide a guide to existing alignment algorithms, and comprehensively benchmark existing algorithms on both synthetic and real-world biological data, finding dramatic differences between existing algorithms in the quality of the alignments they produce. Additionally, we find that many of these tools are inconvenient to use in practice, and there remains a need for easy-to-use, cross-platform tools for performing network alignment.

Development and Implementation of a Real-Time See-Through-Wall Radar System Based on FPGA

Abstract: This paper presents the development of a low-cost real-time ultrawideband (UWB) see-through-wall (STW) imaging radar system. The designs of the microwave front end, the UWB data acquisition, and the system integration are discussed in detail. As for the most challenging task, the UWB data acquisition, we introduce a custom low-cost module based on commercial field-programmable gate array (FPGA) boards and low-speed analog-to-digital converters. The introduced module does not require a custom implementation of high-speed wideband mixed-signal circuitry but only depends on the FPGA firmware design, which favors a rapid system prototyping. The data acquisition module accomplishes a 100-ps equivalent-time sampling resolution at 100-Msamples/s real-time rate, while the developed STW system provides a 2-D real-time view of motion with a 1.5-ms speed behind walls. The system allows for an easy reconfiguration to support multiple operating frequency ranges, pulse sampling resolutions, and array deployments, thus providing a tremendous experimental flexibility. Our studies indicate that utilizing available technologies and off-the-shelf components could produce a practical stand-alone STW system at reasonable design effort and cost, which will lead to a better understanding of the challenging problems associated with STW technology.

Barriers and Bridges to Prevention and Control of Dengue: The Need for a Social–Ecological Approach

Abstract: This article critically examines how programs for the prevention and control of dengue fever have been conducted in the absence of an integrated approach, and considers the social and ecological factors influencing their effectiveness. Despite recognition of dengue fever as the most important arboviral disease affecting humans, and in spite of a greater emphasis on community-based control approaches, the burden placed on the communities, countries, and regions affected by this disease continues to rise. In considering historical experience in the Americas and the Asia-Pacific region, as well as the global forces that are exerting new pressures, the important elements of successful control programs are identified as community ownership, partnership with government, leadership, scalability, and control of immature mosquitoes. The key barriers to the exchange of knowledge and the transdisciplinary cooperation necessary for sustainable dengue control are rooted in differences in values among policy-makers, citizens, and scientists and are repeatedly expressed in technical, economic, cultural, geographic, and political dimensions. Through consideration of case studies in Cuba, Guatemala, Singapore, Thailand, Indonesia, and Vietnam, the limitations of control approaches that fail to take into account the complexities of ecological and social systems are presented. Bridges to effective control are identified as the basis for adaptability, both of control programs to the mosquito vector’s changing behavior and of education programs to public, regional and local particularities, as well as transdisciplinarity, community empowerment, the ability to scale local experiences up to the macro-level, and the capacity to learn from experience to achieve sustainability.