University of Colorado Colorado Springs

About: University of Colorado Colorado Springs is a education organization based out in Colorado Springs, Colorado, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 6664 authors who have published 10872 publications receiving 323416 citations. The organization is also known as: UCCS & University of Colorado at Colorado Springs.

Phaseolus beans: impact on glycaemic response and chronic disease risk in human subjects.

Abstract: Consumption of Phaseolus vulgaris bean species such as pinto, black, navy or kidney may be beneficial in the prevention and treatment of chronic diseases. In particular, conditions that are promoted by increased glycaemic stress (hyperglycaemia and hyperinsulinaemia) including diabetes, CVD and cancer seem to be reduced in individuals who eat more of these beans. The present paper discusses the influence of P. vulgaris species on glycaemic response and the impact that relationship may have on the risk of developing diabetes, CVD and cancer.

The Balloon Array for RBSP Relativistic Electron Losses (BARREL)

Abstract: BARREL is a multiple-balloon investigation designed to study electron losses from Earth’s Radiation Belts. Selected as a NASA Living with a Star Mission of Opportunity, BARREL augments the Radiation Belt Storm Probes mission by providing measurements of relativistic electron precipitation with a pair of Antarctic balloon campaigns that will be conducted during the Austral summers (January-February) of 2013 and 2014. During each campaign, a total of 20 small (∼20 kg) stratospheric balloons will be successively launched to maintain an array of ∼5 payloads spread across ∼6 hours of magnetic local time in the region that magnetically maps to the radiation belts. Each balloon carries an X-ray spectrometer to measure the bremsstrahlung X-rays produced by precipitating relativistic electrons as they collide with neutrals in the atmosphere, and a DC magnetometer to measure ULF-timescale variations of the magnetic field. BARREL will provide the first balloon measurements of relativistic electron precipitation while comprehensive in situ measurements of both plasma waves and energetic particles are available, and will characterize the spatial scale of precipitation at relativistic energies. All data and analysis software will be made freely available to the scientific community.

Terror Management Theory and Research: How the Desire for Death Transcendence Drives Our Strivings for Meaning and Significance

Abstract: Science tells us that humans are merely animals that evolved to survive long enough to reproduce and care for offspring before dying. Yet, people want to view life as something more and accomplish something more: to have lives that are meaningful and significant. According to terror management theory, these desires spring from the human awareness of our own vulnerability and mortality. This awareness creates a unique ever-present potential for experiencing terror. To manage this potential, cultural worldviews have been constructed to imbue life with meaning and with possibilities for individuals to attain enduring significance (self-esteem). Humans function relatively securely as long as they sustain faith in such a worldview and their value within it because it provides them with the sense that they are not just transient animals fated only to obliteration; rather they will in some way transcend their own death. The theory has been supported by over 500 studies, clarifying how we humans manage this potential terror. We briefly summarize the roots and core of the theory and evidence, and branches of research pertinent to politics, religion, love, family, health, and neuroscience. We conclude by considering how death relates to other threats, and positive forms of terror management.

Transarterial Chemoembolization of Metastatic Colorectal Carcinoma with Drug-Eluting Beads, Irinotecan (DEBIRI): Multi-Institutional Registry.

Abstract: The purpose of this study was to evaluate the patient tolerance and efficacy of delivering locoregional chemotherapy to metastatic colorectal (MC) hepatic metastases via hepatic trans-arterial approach using irinotecan loaded drug eluting beads. This open-label, multi-center, single arm study included 30 MC patients, who had failed first line therapy. Of the 57 total embolization sessions, 12 (21% of sessions) were associated with adverse reactions during or after the treatment. After a median followup of 9 months, response rates by modified RECIST were 75% at 3 months and 66% at 6 months. Hepatic trans-arterial therapy using Irinotecan loaded DC BeadTM was safe and effective in the treatment of MCC as demonstrated by a minimal complication rate and acceptable tumor response.

Heterosexual transmission of HIV in Africa: an empiric estimate.

Abstract: For more than a decade, most experts have assumed that more than 90% of HIV in African adults results from heterosexual transmission. In this exercise, we show how data from studies of risk factors for HIV can be used to estimate the proportion from sexual transmission, and we present our estimates. Calculating two ways from available data, our two point estimates - we do not estimate confidence intervals - are that 25-29% of HIV incidence in African women and 30-35% in men is attributable to sexual transmission; these estimates assume 10% annual epidemic growth. These findings call for reconceptualization of research to more accurately assess routes of HIV transmission.