Institution
University of Colorado Colorado Springs
Education•Colorado Springs, Colorado, United States•
About: University of Colorado Colorado Springs is a education organization based out in Colorado Springs, Colorado, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 6664 authors who have published 10872 publications receiving 323416 citations. The organization is also known as: UCCS & University of Colorado at Colorado Springs.
Topics: Population, Poison control, Thin film, Capacitor, Ferroelectricity
Papers published on a yearly basis
Papers
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TL;DR: The authors report observed 10‐year brachytherapy results in the treatment of 152 consecutive patients with clinically organ‐confined prostate carcinoma.
Abstract: BACKGROUND
The authors report observed 10-year brachytherapy results in the treatment of 152 consecutive patients with clinically organ-confined prostate carcinoma.
METHODS
One hundred and fifty-two consecutive patients with T1-T3, low to high Gleason grade, prostate carcinoma were treated between January 1987 and June 1988 at Northwest Hospital in Seattle, Washington. Their median age was 70 years (range, 53-92 years). Of these 152 patients, 98 (64%) received an iodine-125 implant alone (Group 1), and the remaining 54 patients (36%), who were judged to have a higher risk of extraprostatic extension, also were treated with 45 gray (Gy) of external beam irradiation to the pelvis (Group 2). No patient underwent lymph node sampling, and none received androgen ablation therapy. Multivariate regression and the Mann-Whitney rank sum test were used for statistical analysis. Preoperative patient data with associated success or failure outcomes at 10 years after treatment were used for training and validating a back-propagation neural network prediction program.
RESULTS
The average preoperative prostate specific antigen (PSA) value, clinical stage, and Gleason grade were 11.0 ng/mL, T2, and 5, respectively. The median posttreatment follow-up was 119 months (range, 3-134 months). Overall survival 10 years after treatment was 65%. At last follow-up only 3 of the 152 patients (2%) had died of prostate carcinoma. Ninety-seven patients (64%) remained clinically and biochemically free of disease at 10 years of follow-up and had an average PSA value of 0.18 ng/mL (range, 0.01-0.5 ng/mL). In these patients a period of 42 months was required to reach the average PSA (0.5 ng/mL). The median to last PSA follow-up was 95 months (range, 3-134 months). Postoperative needle biopsies were negative in 56% of patients, positive in 15% of patients, and not available in 29% of patients. Only 6% of patients developed bone metastasis. At 10 years there was no statistically significant difference in treatment outcome between patients who received iodine-125 alone, and those who received iodine-125 with 45-Gy external beam irradiation (P = 0.08). Nevertheless, in these two groups preoperative PSA, stage, and Gleason grade were significantly different (P < 0.01). In the artificial neural network analysis, pretreatment serum PSA was the most accurate predictor of disease-free survival.
CONCLUSIONS
Percutaneous prostate brachytherapy is a valid and efficient option for treating patients with clinically organ-confined, low to high Gleason grade, prostate carcinoma. Observed 10-year follow-up documents serum PSA levels superior to those reported in several published external beam irradiation series, and comparable to those published in a number of published radical prostatectomy series. Cancer 1998;83:989-1001. © 1998 American Cancer Society.
330 citations
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11 Sep 2006TL;DR: A systematic review of empirical studies concerning the effectiveness of elicitation techniques, and the subsequent aggregation of empirical evidence gathered from those studies, finds that interviews, preferentially structured, appear to be one of the most effective elicit techniques.
Abstract: This paper reports a systematic review of empirical studies concerning the effectiveness of elicitation techniques, and the subsequent aggregation of empirical evidence gathered from those studies. The most significant results of the aggregation process are as follows: (1) Interviews, preferentially structured, appear to be one of the most effective elicitation techniques; (2) Many techniques often cited in the literature, like card sorting, ranking or thinking aloud, tend to be less effective than interviews; (3) Analyst experience does not appear to be a relevant factor; and (4) The studies conducted have not found the use of intermediate representations during elicitation to have significant positive effects. It should be noted that, as a general rule, the studies from which these results were aggregated have not been replicated, and therefore the above claims cannot be said to be absolutely certain. However, they can be used by researchers as pieces of knowledge to be further investigated and by practitioners in development projects, always taking into account that they are preliminary findings.
329 citations
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TL;DR: Mortality salience showed that, among participants high in need for closure, mortality salience led to decreased liking for a stereotype-inconsistent gay man, and this pattern replicated with evaluations of stereotype-confirming or stereotype-disconfirming men and women.
Abstract: If stereotypes function to protect people against death-related concerns, then mortality salience should increase stereotypic thinking and preferences for stereotype-confirming individuals. Study 1 demonstrated that mortality salience increased stereotyping of Germans. In Study 2, it increased participants' tendency to generate more explanations for stereotype-inconsistent than stereotype-consistent gender role behavior. In Study 3, mortality salience increased participants' liking for a stereotype-consistent African American and decreased their liking for a stereotype-inconsistent African American; control participants exhibited the opposite preference. Study 4 replicated this pattern with evaluations of stereotype-confirming or stereotype-disconfirming men and women. Study 5 showed that, among participants high in need for closure, mortality salience led to decreased liking for a stereotype-inconsistent gay man.
327 citations
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TL;DR: The archaeological record documents an evolutionary sequence that begins with ape-equivalent spatial abilities 2.5 million years ago and ends with the appearance of modern abilities in the still remote past of 400,000 years ago, which reveals two major episodes in the evolution in spatial ability.
Abstract: Archaeology can provide two bodies of information relevant to the understanding of the evolution of human cognition--the timing of developments, and the evolutionary context of these developments. The challenge is methodological. Archaeology must document attributes that have direct implications for underlying cognitive mechanisms. One example of such a cognitive archaeology is found in spatial cognition. The archaeological record documents an evolutionary sequence that begins with ape-equivalent spatial abilities 2.5 million years ago and ends with the appearance of modern abilities in the still remote past of 400,000 years ago. The timing of these developments reveals two major episodes in the evolution in spatial ability, one, 1.5 million years ago and the other, one million years later. The two episodes of development in spatial cognition had very different evolutionary contexts. The first was associated with the shift to an open country adaptive niche that occurred early in the time range of Homo erectus. The second was associated with no clear adaptive shift, though it does appear to have coincided with the invasion of more hostile environments and the appearance of systematic hunting of large mammals. Neither, however, occurred in a context of modern hunting and gathering.
326 citations
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TL;DR: In this paper, a model of how spiritual values can be integrated into organizations and then assess how this model predicts organizational behavior in one company, Southwest Airlines (SWA), and the application of this model provides insights into how and under what specific conditions spiritual value can positively impact both profitability and employee attitudes in organizations.
Abstract: One important issue is whether spirituality in the workplace can be used only to benefit employees or can it be developed also to the advantage of organizations? The purpose of this article is to articulate a model of how spiritual values can be integrated into organizations and then assess how this model predicts organizational behavior in one company, Southwest Airlines (SWA). The application of this model provides insights into how and under what specific conditions spiritual values can positively impact both profitability and employee attitudes in organizations. Implications for both research and practice are discussed.
326 citations
Authors
Showing all 6706 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jeff Greenberg | 105 | 542 | 43600 |
James F. Scott | 99 | 714 | 58515 |
Martin Wikelski | 89 | 420 | 25821 |
Neil W. Kowall | 89 | 279 | 34943 |
Ananth Dodabalapur | 85 | 394 | 27246 |
Tom Pyszczynski | 82 | 246 | 30590 |
Patrick S. Kamath | 78 | 466 | 31281 |
Connie M. Weaver | 77 | 473 | 30985 |
Alejandro Lucia | 75 | 680 | 23967 |
Michael J. McKenna | 70 | 356 | 16227 |
Timothy J. Craig | 69 | 458 | 18340 |
Sheldon Solomon | 67 | 150 | 23916 |
Michael H. Stone | 65 | 370 | 16355 |
Christopher J. Gostout | 65 | 334 | 13593 |
Edward T. Ryan | 60 | 303 | 11822 |