Institution
University of Colorado Denver
Education•Denver, Colorado, United States•
About: University of Colorado Denver is a education organization based out in Denver, Colorado, United States. It is known for research contribution in the topics: Population & Health care. The organization has 27444 authors who have published 57213 publications receiving 2539937 citations. The organization is also known as: CU Denver & UCD.
Topics: Population, Health care, Poison control, Medicine, Diabetes mellitus
Papers published on a yearly basis
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TL;DR: It is reported that a DEVD motif-specific caspase that cleaves MEKK-1 specifically is activated when cells lose matrix contact, which activates more caspases activity, comprising a positive feedback loop.
535 citations
Veterans Health Administration1, University of Colorado Denver2, Harvard University3, University of Illinois at Chicago4, American College of Surgeons5, University of Virginia6, University of Michigan7, Emory University8, Wayne State University9, University of Utah10, United States Department of Veterans Affairs11
TL;DR: The VA NSQIP methods and risk models in general and vascular surgery were fully applicable to private sector hospitals and 30-day postoperative morbidity or mortality in PS hospitals was reduced with the implementation of theNSQIP.
Abstract: Background:The Veterans Affairs ’ (VA) National Surgical Quality Improvement Program (NSQIP) has been associated with significant reductions in postoperative morbidity and mortality. We sought to determine if NSQIP methods and risk models were applicable to private sector (PS) hospitals and if imple
534 citations
TL;DR: It has been 30 years since the surgeon general of the United States released the first report of the Advisory Committee on Smoking and Health and in each of the subsequent reports, cigarette smoking has been identified as the most important source of preventable morbidity and premature mortality in theUnited States.
Abstract: It has been 30 years since the surgeon general of the United States released the first report of the Advisory Committee on Smoking and Health. In each of the subsequent reports, cigarette smoking has been identified as the most important source of preventable morbidity and premature mortality in the United States. A total of 418,690 deaths in the United States were attributed to smoking in 19901. That figure included approximately twice as many male as female smokers. Of the 2,148,000 U.S. residents who died in 1990, approximately half died of particular preventable causes2 (Table 1). The prominence of tobacco . . .
534 citations
TL;DR: In this paper, the authors use theoretical and empirical approaches to define corporate environmental performance and consider how well existing measures operationalize the construct and suggest a need for explicit environmental performance metrics in order to provide stakeholders with more reliable, consistent, and accurate information for comparing companies and making key strategic decisions.
533 citations
TL;DR: It is demonstrated that Cdk2-E activity is required for centrosome duplication during S phase and a mechanism that could coordinate centrosomes reproduction with cycles of DNA synthesis and mitosis is suggested.
Abstract: The abnormally high number of centrosomes found in many human tumor cells can lead directly to aneuploidy and genomic instability through the formation of multipolar mitotic spindles. To facilitate investigation of the mechanisms that control centrosome reproduction, a frog egg extract arrested in S phase of the cell cycle that supported repeated assembly of daughter centrosomes was developed. Multiple rounds of centrosome reproduction were blocked by selective inactivation of cyclin-dependent kinase 2-cyclin E (Cdk2-E) and were restored by addition of purified Cdk2-E. Confocal immunomicroscopy revealed that cyclin E was localized at the centrosome. These results demonstrate that Cdk2-E activity is required for centrosome duplication during S phase and suggest a mechanism that could coordinate centrosome reproduction with cycles of DNA synthesis and mitosis.
532 citations
Authors
Showing all 27683 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Matthew Meyerson | 194 | 553 | 243726 |
| Charles A. Dinarello | 190 | 1058 | 139668 |
| Gad Getz | 189 | 520 | 247560 |
| Gordon B. Mills | 187 | 1273 | 186451 |
| Jasvinder A. Singh | 176 | 2382 | 223370 |
| David Haussler | 172 | 488 | 224960 |
| Donald G. Truhlar | 165 | 1518 | 157965 |
| Charles M. Perou | 156 | 573 | 202951 |
| David Cella | 156 | 1258 | 106402 |
| Bruce D. Walker | 155 | 779 | 86020 |
| Marco A. Marra | 153 | 620 | 184684 |
| Thomas E. Starzl | 150 | 1625 | 91704 |
| Marc Humbert | 149 | 1184 | 100577 |
| Rajesh Kumar | 149 | 4439 | 140830 |
| Martin J. Blaser | 147 | 820 | 104104 |