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Institution

University of Copenhagen

EducationCopenhagen, Denmark
About: University of Copenhagen is a education organization based out in Copenhagen, Denmark. It is known for research contribution in the topics: Population & Galaxy. The organization has 57645 authors who have published 149740 publications receiving 5903093 citations. The organization is also known as: Copenhagen University & Københavns Universitet.


Papers
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Journal ArticleDOI
30 Jul 2015-Nature
TL;DR: Using low-coverage whole-genome sequencing of 5,303 Chinese women with recurrent MDD selected to reduce phenotypic heterogeneity, and 5,337 controls screened to exclude MDD, two loci contributing to risk of MDD on chromosome 10 are identified: one near the SIRT1 gene and the other in an intron of the LHPP gene.
Abstract: Genomic analysis of 5,303 Chinese women with recurrent major depressive disorder (MDD) enables the identification and replication of two genome-wide significant loci contributing to risk of MDD on chromosome 10: one near the SIRT1 gene; the other in an intron of the LHPP gene.

745 citations

Journal ArticleDOI
10 Dec 2010-Science
TL;DR: A group of papers analyzes pathogen genomes to find the roots of virulence, opportunism, and life-style determinants in plant pathogens, suggesting that most effectors represent species-specific adaptations.
Abstract: Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations.

744 citations

Journal ArticleDOI
12 Nov 2020-Cell
TL;DR: A model in which viral attachment and infection involves heparan sulfate-dependent enhancement of binding to ACE2 is suggested, in which Manipulation of hepara sulfate or inhibition of viral adhesion by exogenous heparin presents new therapeutic opportunities.

744 citations

Book
22 Dec 2007
TL;DR: The Phenomenological Mind as discussed by the authors is the first book to properly introduce fundamental questions about the mind from the perspective of phenomenology, including what is phenomenology and what is personal identity.
Abstract: The Phenomenological Mind is the first book to properly introduce fundamental questions about the mind from the perspective of phenomenology. Key questions and topics covered include: What is phenomenology? naturalizing phenomenology and the empirical cognitive sciences phenomenology and consciousness consciousness and self-consciousness, including perception and action time and consciousness, including William James intentionality the embodied mind action knowledge of other minds situated and extended minds phenomenology and personal identity Interesting and important examples are used throughout, including phantom limb syndrome, blindsight and self-disorders in schizophrenia, making The Phenomenological Mind an ideal introduction to key concepts in phenomenology, cognitive science and philosophy of mind.

743 citations

Journal ArticleDOI
21 Jun 2012-Nature
TL;DR: Spectroscopic metallicities of the host stars of 226 small exoplanet candidates discovered by NASA's Kepler mission are reported, finding that planets with radii less than four Earth radii form around host stars with a wide range of metallicities (but on average a metallicity close to that of the Sun), whereas large planets preferentially form around stars with higher metallicities.
Abstract: The abundance of heavy elements (metallicity) in the photospheres of stars similar to the Sun provides a 'fossil' record of the chemical composition of the initial protoplanetary disk. Metal-rich stars are much more likely to harbour gas giant planets(1-4), supporting the model that planets form by accumulation of dust and ice particles(5). Recent ground-based surveys suggest that this correlation is weakened for Neptunian-sized planets(4,6-9). However, how the relationship between size and metallicity extends into the regime of terrestrial-sized exoplanets is unknown. Here we report spectroscopic metallicities of the host stars of 226 small exoplanet candidates discovered by NASA's Kepler mission(10), including objects that are comparable in size to the terrestrial planets in the Solar System. We find that planets with radii less than four Earth radii form around host stars with a wide range of metallicities (but on average a metallicity close to that of the Sun), whereas large planets preferentially form around stars with higher metallicities. This observation suggests that terrestrial planets may be widespread in the disk of the Galaxy, with no special requirement of enhanced metallicity for their formation.

743 citations


Authors

Showing all 58387 results

NameH-indexPapersCitations
Michael Karin236704226485
Matthias Mann221887230213
Peer Bork206697245427
Ronald Klein1941305149140
Kenneth S. Kendler1771327142251
Dorret I. Boomsma1761507136353
Ramachandran S. Vasan1721100138108
Unnur Thorsteinsdottir167444121009
Mika Kivimäki1661515141468
Jun Wang1661093141621
Anders Björklund16576984268
Gerald I. Shulman164579109520
Jaakko Kaprio1631532126320
Veikko Salomaa162843135046
Daniel J. Jacob16265676530
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023370
20221,266
202110,693
20209,956
20199,189
20188,620