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Institution

University of Córdoba (Spain)

EducationCordova, Spain
About: University of Córdoba (Spain) is a education organization based out in Cordova, Spain. It is known for research contribution in the topics: Population & Catalysis. The organization has 12006 authors who have published 22998 publications receiving 537842 citations. The organization is also known as: University of Córdoba (Spain) & Universidad de Córdoba.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the results of the chemical and electrochemical insertion of lithium ions into the spinel Li4Ti5O12 have been analyzed using 6,7Li NMR, Raman spectroscopy, and X-ray diffraction.
Abstract: Lithium has been inserted into the spinel Li4Ti5O12 by both chemical and electrochemical methods. The cation distribution in the lithiated phases has been analyzed by 6,7Li NMR, Raman spectroscopy, and X-ray diffraction, and the distribution in the chemically inserted compound has been analyzed additionally by neutron diffraction. A refinement of structural parameters has been carried out by applying the Rietveld method to the neutron diffraction pattern. It is shown that the two insertion methods are based on different mechanisms. Chemically inserted lithium ions are trapped in the (48f) sites of the spinel structure from which they cannot be extracted by electrochemical means. In contrast to the electrochemical Li-insertion, which is accompanied by a spinel to rocksalt phase transition, no such structural change is found for chemical insertion. The consequences of the two different mechanisms for the reversibility of the insertion process are discussed.

301 citations

Journal ArticleDOI
TL;DR: Those compounds known to activate or inhibit sirtuins, discussing the data that support the use of sirtuin‐based therapies and noting the growing interest in the discovery of small molecules modifying their activities.
Abstract: Sirtuins 1-7 (SIRT1-7) belong to the third class of deacetylase enzymes, which are dependent on NAD(+) for activity. Sirtuins activity is linked to gene repression, metabolic control, apoptosis and cell survival, DNA repair, development, inflammation, neuroprotection, and healthy aging. Because sirtuins modulation could have beneficial effects on human diseases there is a growing interest in the discovery of small molecules modifying their activities. We review here those compounds known to activate or inhibit sirtuins, discussing the data that support the use of sirtuin-based therapies. Almost all sirtuin activators have been described only for SIRT1. Resveratrol is a natural compound which activates SIRT1, and may help in the treatment or prevention of obesity, and in preventing tumorigenesis and the aging-related decline in heart function and neuronal loss. Due to its poor bioavailability, reformulated versions of resveratrol with improved bioavailability have been developed (resVida, Longevinex(®) , SRT501). Molecules that are structurally unrelated to resveratrol (SRT1720, SRT2104, SRT2379, among others) have been also developed to stimulate sirtuin activities more potently than resveratrol. Sirtuin inhibitors with a wide range of core structures have been identified for SIRT1, SIRT2, SIRT3 and SIRT5 (splitomicin, sirtinol, AGK2, cambinol, suramin, tenovin, salermide, among others). SIRT1 inhibition has been proposed in the treatment of cancer, immunodeficiency virus infections, Fragile X mental retardation syndrome and for preventing or treating parasitic diseases, whereas SIRT2 inhibitors might be useful for the treatment of cancer and neurodegenerative diseases.

298 citations

Journal ArticleDOI
TL;DR: In this article, surface soil samples with a range of poorly crystalline Fe (hydr)oxide contents were characterized for water-stable aggregates > 0.25 mm (WSA), mean-weighted diameter (MWD), soil organic C (OC), particle-size distribution, pH, exchangeable cations, citrate/bicarbonate/dithionite (subscript d), and acid ammonium oxalate extractable Fe, Al, and Si.
Abstract: Differences in crystallinity may explain why total Fe (hydr)oxide content has a variable effect on aggregate stability. Therefore, surface soil samples with a range of poorly crystalline Fe (hydr)oxide contents were characterized for water-stable aggregates >0.25 mm (WSA), mean-weighted diameter (MWD), soil organic C (OC), particle-size distribution, pH, exchangeable cations, citrate/bicarbonate/dithionite (subscript d), and acid ammonium oxalate (subscript o) extractable Fe, Al, and Si. The WSA and MWD range from 23 to 95%, and 0.3 to 5.1 mm, respectively. The effects of Fe o (1.1-6.8 g kg -1 ), Fe d (3.2-19.6 g kg -1 ), OC (2.4-24.0 g kg -1 ) and clay (141-467 g kg -1 ) contents on WSA and MWD of both A and B horizons of these soils was studied using linear regression. The poorly crystalline Fe (hydr)oxide (Fe o ) and OC contents are significantly correlated with WSA in the A horizons (r 2 = 0.95, n = 6, p = 0.001, and r 2 = 0.93, n = 6, p = 0.002, respectively) and in the B horizons (r 2 = 0.73, n = 6, p = 0.029, and r 2 = 0.76, n = 6, p = 0.024, respectively). When regressed against MWD, Fe o has an r 2 of 0.89 (n = 6, p = 0.004) in the A, and 0.97 (n = 6, p = 0.000) in the B horizons. The coefficient of determination of MWD vs. OC contents is 0.98 (n = 6, p = 0.000) in the A and 0.79 (n = 6, p = 0.018) in the B horizons. Clay and Fed contents are not significantly correlated to WSA or MWD. Apparently, the Fe o component (poorly crystalline) is more effective than Fed at stabilizing soil aggregates, even though it is present in lower concentrations. The Fe o component appears more important than OC in terms of WSA and MWD for soils with relatively low soil organic matter contents.

298 citations

Journal ArticleDOI
TL;DR: In this article, a systematic review of systematic reviews and meta-analyses on the topic of bullying and cyberbullying is presented, showing that one of every three children is involved in some forms of bullying.

298 citations

Journal ArticleDOI
TL;DR: In this article, the synthesis and characterization of hydrotalcite-like materials is described, and changes taking place during these processes are related to the decrease observed in the specific surface area of the samples upon prolonging the hydrothermal treatment, as well as its development and further decrease upon thermal treatment.
Abstract: The synthesis and characterization of hydrotalcite-like materials is described. As the time to which the samples have been submitted to a hydrothermal treatment is prolonged, a change in the Mg/Al ratio is observed, together with a more ordered structure of the species existing in the interlayer space. Calcination at increasing temperatures leads to decomposition of this compound, with the final formation of MgO and MgAl2O4. Changes taking place during these processes have been related to the decrease observed in the specific surface area of the samples upon prolonging the hydrothermal treatment, as well as its development and further decrease upon thermal treatment.

298 citations


Authors

Showing all 12089 results

NameH-indexPapersCitations
Jose M. Ordovas123102470978
Liang Cheng116177965520
Pedro W. Crous11580951925
Munther A. Khamashta10962350205
Luis Serrano10545242515
Raymond Vanholder10384140861
Carlos Dieguez10154536404
David G. Bostwick9940331638
Leon V. Kochian9526631301
Abhay Ashtekar9436637508
Néstor Armesto9336926848
Manuel Hidalgo9253841330
Rafael de Cabo9131735020
Harald Mischak9044527472
Manuel Tena-Sempere8735123100
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202333
2022133
20211,640
20201,619
20191,517
20181,348