Institution
University of Costa Rica
Education•San José, Costa Rica•
About: University of Costa Rica is a education organization based out in San José, Costa Rica. It is known for research contribution in the topics: Population & Venom. The organization has 9817 authors who have published 16781 publications receiving 238208 citations. The organization is also known as: UCR & Universidad de Costa Rica.
Topics: Population, Venom, Antivenom, Snake venom, Myotoxin
Papers published on a yearly basis
Papers
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TL;DR: The data suggest that the association between MI and adipose tissue AA is not related to dietary intake of (n-6) FAs including linoleic acid, and better understanding of the metabolic factors that increase AA in adipOSE tissue is urgently needed.
Abstract: Arachidonic acid (AA), a precursor of prothrombotic eicosanoids, is potentially atherogenic, but epidemiologic data are scarce. We evaluated the hypothesis that increased AA in adipose tissue is associated with increased risk of nonfatal acute myocardial infarction (MI), and if so, whether this association is related to dietary or adipose tissue linoleic acid. We studied the association between AA and MI in 466 cases of a first nonfatal acute MI, matched on age, gender, and residence to 466 population controls. Fatty acids (FA) were assessed by GC in adipose tissue samples collected from all subjects. Odds ratios (OR) and 95% CI were calculated from multivariate conditional logistic regression models. Subjects in the highest quintile of adipose tissue AA (0.64% of total FA) had a higher risk of nonfatal acute MI than those in the lowest quintile (0.29% of total FA), after adjusting for potential confounders including (n-3) and trans FAs (OR = 1.94, 95% CI: 1.07, 3.53, P for trend = 0.026). Adipose tissue AA was not correlated with dietary AA (r = 0.07), linoleic acid (r = 0.04), or other dietary (n-6) FAs, or with adipose tissue linoleic acid (r = -0.07). These data suggest that the association between MI and adipose tissue AA is not related to dietary intake of (n-6) FAs including linoleic acid. Better understanding of the metabolic factors that increase AA in adipose tissue is urgently needed.
57 citations
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TL;DR: It is concluded that venom of newborn C.d. durissus contains high concentrations of crotoxin and low amounts of hemorrhagic and proteolytic components, and that a drastic ontogenetic change takes place in the venom composition of this subspecies.
57 citations
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University College London1, Paul Sabatier University2, University of Geneva3, Harvard University4, University of Antioquia5, Cayetano Heredia University6, Arizona State University7, Federal University of Paraná8, University of California, Berkeley9, University of Costa Rica10, University of Tarapacá11, Université de Montréal12, Universidade Federal do Rio Grande do Sul13, Swiss Institute of Bioinformatics14, University of Bern15
TL;DR: An integrated analysis of nuclear (autosomal, X‐ and Y‐chromosome) short tandem repeat (STR) data and mtDNA D‐loop sequences obtained in the same set of 22 Native populations suggests an early divergence of Andean and non‐Andean South Americans and at a contrasting demographic history for populations from these regions.
Abstract: We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined Population differentiation is highest in East South America and lowest in Meso America and the Andean region Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions
57 citations
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TL;DR: This minireview summarizes the potential participation of white rot fungi in BPS and presents the potential use of WRF in biodegradation of pollutants, particularly pesticides, and includes a brief description of the enzymatic systems involved in their oxidation.
Abstract: Environmental contamination with pesticides is an undesired consequence of agricultural activities. Biopurification systems (BPS) comprise a novel strategy to degrade pesticides from contaminated wastewaters, consisting of a highly active biological mixture confined in a container or excavation. The design of BPS promotes microbial activity, in particular by white rot fungi (WRF). Due to their physiological features, specifically the production of highly unspecific ligninolytic enzymes and some intracellular enzymatic complexes, WRF show the ability to transform a wide range of organic pollutants. This minireview summarizes the potential participation of WRF in BPS. The first part presents the potential use of WRF in biodegradation of pollutants, particularly pesticides, and includes a brief description of the enzymatic systems involved in their oxidation. The second part presents an outline of BPS, focusing on the elements that influence the participation of WRF in their operation, and includes a summary of the studies regarding the fungal-mediated degradation of pesticides in BPS biomixtures and other solid-phase systems that mimic BPS.
57 citations
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TL;DR: The results document that the SBFS complex is far more taxonomically diverse than previously recognized and provide strong evidence that SBFS species differ in geographic distribution.
Abstract: Sooty blotch and flyspeck (SBFS) fungi on apple fruit were sampled from nine orchards in four midwestern U.S. states during 2000 and 30 orchards in 10 eastern U.S. states during 2005 in order to estimate taxonomic diversity and discern patterns of geographic distribution. Forty apple fruit per orchard were arbitrarily sampled and colonies of each mycelial phenotype were counted on each apple. Representative colonies were isolated, cultures were purified, and DNA was extracted. For representative isolates, the internal transcribed spacer (ITS) and large subunit (LSU) regions of ribosomal DNA were amplified and sequenced. In total, 60 SBFS putative species were identified based on ITS sequences and morphological characteristics; 30 of these were discovered in the 2005 survey. Modified Koch's postulates were fulfilled for all 60 species in an Iowa orchard; colonies resulting from inoculation of apple fruit were matched to the original isolates on the basis of mycelial type and ITS sequence. Parsimon...
57 citations
Authors
Showing all 9922 results
Name | H-index | Papers | Citations |
---|---|---|---|
Alberto Ascherio | 136 | 462 | 69578 |
Gervasio Gomez | 133 | 1844 | 99695 |
Myron M. Levine | 123 | 789 | 60865 |
Hong-Cai Zhou | 114 | 489 | 66320 |
Edward O. Wilson | 101 | 406 | 89994 |
Mary Claire King | 100 | 336 | 47454 |
Olga Martín-Belloso | 86 | 384 | 23428 |
José María Gutiérrez | 84 | 607 | 26779 |
Cesare Montecucco | 84 | 382 | 27738 |
Rodolphe Clérac | 78 | 506 | 22604 |
Kim R. Dunbar | 74 | 470 | 20262 |
Paul J. Hanson | 70 | 251 | 19504 |
Hannia Campos | 69 | 210 | 15164 |
Jean-Pierre Gorvel | 67 | 231 | 15005 |
F. Albert Cotton | 66 | 1023 | 27647 |