University of Cyprus

About: University of Cyprus is a education organization based out in Nicosia, Cyprus. It is known for research contribution in the topics: Large Hadron Collider & Context (language use). The organization has 3624 authors who have published 15157 publications receiving 412135 citations.

Maximizing Cloud Providers' Revenues via Energy Aware Allocation Policies

Abstract: Cloud providers, like Amazon, offer their data centers' computational and storage capacities for lease to paying customers. High electricity consumption, associated with running a data center, not only reflects on its carbon footprint, but also increases the costs of running the data center itself. This paper addresses the problem of maximizing the revenues of Cloud providers by trimming down their electricity costs. As a solution allocation policies which are based on the dynamic powering servers on and off are introduced and evaluated. The policies aim at satisfying the conflicting goals of maximizing the users' experience while minimizing the amount of consumed electricity. The results of numerical experiments and simulations are described, showing that the proposed scheme performs well under different traffic conditions.

The influence of school leadership styles and culture on students' achievement in Cyprus primary schools

Abstract: Purpose – This study aims to examine the validation of both the model of direct effects and the model of indirect effects of principals' leadership on student academic achievement.Design/methodology/approach – A longitudinal study was conducted in which 22 schools, 55 classes and 1,224 Cypriot primary students participated. Specifically, achievements in Greek Language and Mathematics were assessed at the beginning and at the end of the same school year. Moreover, leadership style of school principals and teachers as well as school and classroom culture was measured.Findings – The findings provide some empirical support for the model of direct effects of principals' leadership on student academic achievement. Moreover, student achievement gains were found to be related with five factors at the school level: the principals' human resource leadership style and four dimensions of organizational culture. At the classroom level, three dimensions of learning culture significantly influence student achievement in...

A synthesis of studies searching for school factors: implications for theory and research

Abstract: This paper reports the results of a meta-analysis in which the dynamic model of educational effectiveness is used as a framework to search for school factors associated with student achievement. The methods and results of a synthesis of 67 studies are presented. Findings reveal that effective schools are able to develop policies and take actions in order to improve their teaching practice and learning environment. Factors excluded from the dynamic model were found to be only weakly associated with outcomes. Implications for research on school effectiveness and for improvement of practice are drawn. It is illustrated that this approach of conducting meta-analysis helps us interpret the findings by providing support to the validity of the dynamic model and suggestions for its further development.

Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder

Abstract: Maternal immune activation (MIA) via infection during pregnancy is known to increase risk for autism spectrum disorder (ASD). However, it is unclear how MIA disrupts fetal brain gene expression in ways that may explain this increased risk. Here we examine how MIA dysregulates rat fetal brain gene expression (at a time point analogous to the end of the first trimester of human gestation) in ways relevant to ASD-associated pathophysiology. MIA downregulates expression of ASD-associated genes, with the largest enrichments in genes known to harbor rare highly penetrant mutations. MIA also downregulates expression of many genes also known to be persistently downregulated in the ASD cortex later in life and which are canonically known for roles in affecting prenatally late developmental processes at the synapse. Transcriptional and translational programs that are downstream targets of highly ASD-penetrant FMR1 and CHD8 genes are also heavily affected by MIA. MIA strongly upregulates expression of a large number of genes involved in translation initiation, cell cycle, DNA damage and proteolysis processes that affect multiple key neural developmental functions. Upregulation of translation initiation is common to and preserved in gene network structure with the ASD cortical transcriptome throughout life and has downstream impact on cell cycle processes. The cap-dependent translation initiation gene, EIF4E, is one of the most MIA-dysregulated of all ASD-associated genes and targeted network analyses demonstrate prominent MIA-induced transcriptional dysregulation of mTOR and EIF4E-dependent signaling. This dysregulation of translation initiation via alteration of the Tsc2-mTor-Eif4e axis was further validated across MIA rodent models. MIA may confer increased risk for ASD by dysregulating key aspects of fetal brain gene expression that are highly relevant to pathophysiology affecting ASD.