Institution
University of Dundee
Education•Dundee, United Kingdom•
About: University of Dundee is a education organization based out in Dundee, United Kingdom. It is known for research contribution in the topics: Population & Protein kinase A. The organization has 19258 authors who have published 39640 publications receiving 1919433 citations. The organization is also known as: Universitas Dundensis & Dundee University.
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TL;DR: This comprehensive review points out that there are more than 100 intermediate filament genes and that mutant intermediate filament proteins cause more than 30 diseases.
Abstract: Intermediate filaments provide scaffolding for the cell and protect it against stress. This comprehensive review points out that there are more than 100 intermediate filament genes and that mutant intermediate filament proteins cause more than 30 diseases. Selective expression of these genes in particular tissues accounts for tissue-specific diseases caused by mutant intermediate filament genes, such as epidermolysis bullosa simplex and certain types of cardiomyopathy.
453 citations
TL;DR: The serine residue on the a-sub unit, as well as that on the@subunit, becomes phosphorylated in vivo in response to adrenaline, suggesting that it may have a physiological function.
453 citations
TL;DR: Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children.
Abstract: Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a World Health Organization workshop in 1999 (published in 2001). ARIA has reclassified AR as mild/moderate-severe and intermittent/persistent. This classification closely reflects patients' needs and underlines the close relationship between rhinitis and asthma. Patients, clinicians, and other health care professionals are confronted with various treatment choices for the management of AR. This contributes to considerable variation in clinical practice, and worldwide, patients, clinicians, and other health care professionals are faced with uncertainty about the relative merits and downsides of the various treatment options. In its 2010 Revision, ARIA developed clinical practice guidelines for the management of AR and asthma comorbidities based on the Grading of Recommendation, Assessment, Development and Evaluation (GRADE) system. ARIA is disseminated and implemented in more than 50 countries of the world. Ten years after the publication of the ARIA World Health Organization workshop report, it is important to make a summary of its achievements and identify the still unmet clinical, research, and implementation needs to strengthen the 2011 European Union Priority on allergy and asthma in children.
453 citations
University of Oxford1, Chongqing Medical University2, University of Modena and Reggio Emilia3, University of Melbourne4, University of Dundee5, University of Sydney6, Technische Universität München7, VU University Amsterdam8, Pierre-and-Marie-Curie University9, Centre for Addiction and Mental Health10, University of Toronto11, Appalachian State University12
TL;DR: Comparisons of antidepressants and placebo for major depressive disorder in young people aimed at finding fluoxetine is probably the best option to consider when a pharmacological treatment is indicated and the quality of evidence was rated as very low in most comparisons.
452 citations
TL;DR: OMERO is a software platform that enables access to and use of a wide range of biological data, and its design and flexibility have enabled its use for light- microscopy, high-content-screening, electron-microscopy and even non-image-genotype data.
Abstract: The Open Microscopy Environment Remote Objects (OMERO) software platform provides a server-based system for managing and analyzing microscopy images and non-image data.
452 citations
Authors
Showing all 19404 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Matthias Mann | 221 | 887 | 230213 |
| Mark I. McCarthy | 200 | 1028 | 187898 |
| Stefan Schreiber | 178 | 1233 | 138528 |
| Kenneth C. Anderson | 178 | 1138 | 126072 |
| Masayuki Yamamoto | 171 | 1576 | 123028 |
| Salvador Moncada | 164 | 495 | 138030 |
| Jorge E. Cortes | 163 | 2784 | 124154 |
| Andrew P. McMahon | 162 | 415 | 90650 |
| Philip Cohen | 154 | 555 | 110856 |
| Dirk Inzé | 149 | 647 | 74468 |
| Andrew T. Hattersley | 146 | 768 | 106949 |
| Antonio Lanzavecchia | 145 | 408 | 100065 |
| Kim Nasmyth | 142 | 294 | 59231 |
| David Price | 138 | 1687 | 93535 |
| Dario R. Alessi | 136 | 354 | 74753 |