Institution
University of East Anglia
Education•Norwich, Norfolk, United Kingdom•
About: University of East Anglia is a education organization based out in Norwich, Norfolk, United Kingdom. It is known for research contribution in the topics: Population & Climate change. The organization has 13250 authors who have published 37504 publications receiving 1669060 citations. The organization is also known as: UEA.
Topics: Population, Climate change, Randomized controlled trial, Health care, Psychological intervention
Papers published on a yearly basis
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TL;DR: Together, these processes act to maintain brain homeostasis and play important roles in neuronal stress adaptation and thus polyphenols have the potential to prevent the progression of neurodegenerative pathologies.
Abstract: Accumulating evidence suggests that diet and lifestyle can play an important role in delaying the onset or halting the progression of age-related health disorders and to improve cognitive function. In particular, polyphenols have been reported to exert their neuroprotective actions through the potential to protect neurons against injury induced by neurotoxins, an ability to suppress neuroinflammation, and the potential to promote memory, learning, and cognitive function. Despite significant advances in our understanding of the biology of polyphenols, they are still mistakenly regarded as simply acting as antioxidants. However, recent evidence suggests that their beneficial effects involve decreases in oxidative/inflammatory stress signaling, increases in protective signaling and neurohormetic effects leading to the expression of genes that encode antioxidant enzymes, phase-2 enzymes, neurotrophic factors, and cytoprotective proteins. Specific examples of such pathways include the sirtuin-FoxO pathway, the NF-κB pathway, and the Nrf-2/ARE pathway. Together, these processes act to maintain brain homeostasis and play important roles in neuronal stress adaptation and thus polyphenols have the potential to prevent the progression of neurodegenerative pathologies.
300 citations
TL;DR: In this article, a simple method for the fast synthesis of highly photoluminescent InP and InP/ZnS core-shell nanocrystals (NCs) covering a wide range of emissions from blue to the near infrared.
Abstract: We report a simple method for the fast synthesis of highly photoluminescent InP and InP/ZnS core–shell nanocrystals (NCs) covering a wide range of emissions from blue to the near infrared. Both InP and InP/ZnS NCs were prepared in one-step, in a one-pot reaction within 20 min using an InCl3 complex as a precursor and zinc carboxylate as an initiator and stabilizer. The quantum yields of the InP and InP/ZnS NCs were 30% and 60%, respectively. This new synthetic method allows fast and reproducible preparation of InP and InP/ZnS NCs with a quality comparable to that of the frequently used CdSe-based ones. It is anticipated that these particles can be used to replace CdSe for many applications.
300 citations
TL;DR: In this article, a non-hierarchial clustering of 1000 mb isobaric trajectories, using squared Euclidean distance as a similarity measure, leads to the identification of a finite number of distinct synoptic patterns.
300 citations
TL;DR: The origins of the magnetic susceptibility variations of the Chinese loess and paleosols are explored by scanning and transmission electron microscopy of magnetic extracts, and by magnetic modeling of magnetic hysteresis data, to provide quantified estimates of the major magnetic components.
299 citations
University of Utah1, University of Colorado Denver2, Oregon Health & Science University3, Harvard University4, University of California, San Diego5, University of Texas Health Science Center at Houston6, Medical College of Wisconsin7, Medical University of South Carolina8, Northwestern University9, Emory University10, University of Pennsylvania11, University of São Paulo12, Ghent University13, Sun Yat-sen University14, Karolinska Institutet15, University of Chicago16, Rush University Medical Center17, University of Barcelona18, University of California, Los Angeles19, Vanderbilt University20, University of Arizona21, University of Kansas22, Université de Montréal23, University of Auckland24, Rutgers University25, University of Amsterdam26, Columbia University27, Eastern Virginia Medical School28, University of New South Wales29, Katholieke Universiteit Leuven30, Guy's Hospital31, Stanford University32, University of British Columbia33, Mayo Clinic34, Johns Hopkins University35, Korea University36, Uniformed Services University of the Health Sciences37, Jikei University School of Medicine38, University of Washington39, University of Siena40, University of East Anglia41, University of Adelaide42, Pusan National University43, University of Calgary44, University of Cincinnati45, University of North Carolina at Chapel Hill46, Cleveland Clinic47, University of Winnipeg48, Chulalongkorn University49, Cornell University50, National University of Singapore51, University of Alabama at Birmingham52, University of Alberta53, Capital Medical University54
TL;DR: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in the understanding and treatment of rhinologic disease.
Abstract: I. Executive summary BACKGROUND: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR-RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR-RS-2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence-based findings of the document. Methods ICAR-RS presents over 180 topics in the forms of evidence-based reviews with recommendations (EBRRs), evidence-based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results ICAR-RS-2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence-based management algorithm is provided. Conclusion This ICAR-RS-2021 executive summary provides a compilation of the evidence-based recommendations for medical and surgical treatment of the most common forms of RS.
299 citations
Authors
Showing all 13512 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| George Davey Smith | 224 | 2540 | 248373 |
| Nicholas J. Wareham | 212 | 1657 | 204896 |
| Cyrus Cooper | 204 | 1869 | 206782 |
| Kay-Tee Khaw | 174 | 1389 | 138782 |
| Phillip A. Sharp | 172 | 614 | 117126 |
| Rory Collins | 162 | 489 | 193407 |
| William J. Sutherland | 148 | 966 | 94423 |
| Shah Ebrahim | 146 | 733 | 96807 |
| Kenneth M. Yamada | 139 | 446 | 72136 |
| Martin McKee | 138 | 1732 | 125972 |
| David Price | 138 | 1687 | 93535 |
| Sheila Bingham | 136 | 519 | 67332 |
| Philip Jones | 135 | 644 | 90838 |
| Peter M. Rothwell | 134 | 779 | 67382 |
| Ivan Reid | 131 | 1318 | 85123 |