Institution
University of East Anglia
Education•Norwich, Norfolk, United Kingdom•
About: University of East Anglia is a education organization based out in Norwich, Norfolk, United Kingdom. It is known for research contribution in the topics: Population & Climate change. The organization has 13250 authors who have published 37504 publications receiving 1669060 citations. The organization is also known as: UEA.
Topics: Population, Climate change, Randomized controlled trial, Health care, Psychological intervention
Papers published on a yearly basis
Papers
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TL;DR: The performance of these instruments were compared by sequencing an isolate of Escherichia coli O104:H4, which caused an outbreak of food poisoning in Germany in 2011, and the MiSeq had the highest throughput per run and lowest error rates.
Abstract: Three benchtop high-throughput sequencing instruments are now available. The 454 GS Junior (Roche), MiSeq (Illumina) and Ion Torrent PGM (Life Technologies) are laser-printer sized and offer modest set-up and running costs. Each instrument can generate data required for a draft bacterial genome sequence in days, making them attractive for identifying and characterizing pathogens in the clinical setting. We compared the performance of these instruments by sequencing an isolate of Escherichia coli O104:H4, which caused an outbreak of food poisoning in Germany in 2011. The MiSeq had the highest throughput per run (1.6 Gb/run, 60 Mb/h) and lowest error rates. The 454 GS Junior generated the longest reads (up to 600 bases) and most contiguous assemblies but had the lowest throughput (70 Mb/run, 9 Mb/h). Run in 100-bp mode, the Ion Torrent PGM had the highest throughput (80–100 Mb/h). Unlike the MiSeq, the Ion Torrent PGM and 454 GS Junior both produced homopolymer-associated indel errors (1.5 and 0.38 errors per 100 bases, respectively).
1,346 citations
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TL;DR: The first World report on ageing and health is released, reviewing current knowledge and gaps and providing a public health framework for action, built around a redefinition of healthy ageing that centres on the notion of functional ability.
1,341 citations
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TL;DR: In this paper, a framework for analyzing social vulnerability is outlined, an aspect largely underemphasized in assessments of the impacts of climate change and climate extremes, which is defined as the exposure of individuals or collective groups to livelihood stress as a result of environmental change.
1,335 citations
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TL;DR: In this article, the authors present a range of climate change scenarios for Africa, focusing on changes in both continental and regional seasonal-mean temperature and rainfall, and estimate the associated changes in global CO2 concentration and global mean sea-level change.
Abstract: This paper reviews observed (1900-2000) and possible future (2000-2100) continent- wide changes in temperature and rainfall for Africa. For the historic period we draw upon a new observed global climate data set which allows us to explore aspects of regional climate change related to diurnal temperature range and rainfall variability. The latter includes an investigation of regions where seasonal rainfall is sensitive to El Nino climate variability. This review of past climate change provides the context for our scenarios of future greenhouse gas-induced climate change in Africa. These scenarios draw upon the draft emissions scenarios prepared for the Intergovernmental Panel on Climate Change's Third Assessment Report, a suite of recent global climate model experi- ments, and a simple climate model to link these 2 sets of analyses. We present a range of 4 climate futures for Africa, focusing on changes in both continental and regional seasonal-mean temperature and rainfall. Estimates of associated changes in global CO2 concentration and global-mean sea-level change are also supplied. These scenarios draw upon some of the most recent climate modelling work. We also identify some fundamental limitations to knowledge with regard to future African cli- mate. These include the often poor representation of El Nino climate variability in global climate models, and the absence in these models of any representation of regional changes in land cover and dust and biomass aerosol loadings. These omitted processes may well have important consequences for future African climates, especially at regional scales. We conclude by discussing the value of the sort of climate change scenarios presented here and how best they should be used in national and regional vulnerability and adaptation assessments.
1,330 citations
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Moss Landing Marine Laboratories1, Monterey Bay Aquarium Research Institute2, University of Miami3, University of East Anglia4, Plymouth Marine Laboratory5, University of Wisconsin-Madison6, University of Southern California7, University of Hawaii at Manoa8, Ensenada Center for Scientific Research and Higher Education9
TL;DR: Observations provide unequivocal support for the hypothesis that phytoplankton growth in this oceanic region is limited by iron bioavailability.
Abstract: The seeding of an expanse of surface waters in the equatorial Pacific Ocean with low concentrations of dissolved iron triggered a massive phytoplankton bloom which consumed large quantities of carbon dioxide and nitrate that these microscopic plants cannot fully utilize under natural conditions. These and other observations provide unequivocal support for the hypothesis that phytoplankton growth in this oceanic region is limited by iron bioavailability.
1,318 citations
Authors
Showing all 13512 results
Name | H-index | Papers | Citations |
---|---|---|---|
George Davey Smith | 224 | 2540 | 248373 |
Nicholas J. Wareham | 212 | 1657 | 204896 |
Cyrus Cooper | 204 | 1869 | 206782 |
Kay-Tee Khaw | 174 | 1389 | 138782 |
Phillip A. Sharp | 172 | 614 | 117126 |
Rory Collins | 162 | 489 | 193407 |
William J. Sutherland | 148 | 966 | 94423 |
Shah Ebrahim | 146 | 733 | 96807 |
Kenneth M. Yamada | 139 | 446 | 72136 |
Martin McKee | 138 | 1732 | 125972 |
David Price | 138 | 1687 | 93535 |
Sheila Bingham | 136 | 519 | 67332 |
Philip Jones | 135 | 644 | 90838 |
Peter M. Rothwell | 134 | 779 | 67382 |
Ivan Reid | 131 | 1318 | 85123 |