University of East Anglia

About: University of East Anglia is a education organization based out in Norwich, Norfolk, United Kingdom. It is known for research contribution in the topics: Population & Climate change. The organization has 13250 authors who have published 37504 publications receiving 1669060 citations. The organization is also known as: UEA.

Metalloproteinases in biology and pathology of the nervous system

Abstract: Matrix metalloproteinases (MMPs) have been implicated in several diseases of the nervous system. Here we review the evidence that supports this idea and discuss the possible mechanisms of MMP action. We then consider some of the beneficial functions of MMPs during neural development and speculate on their roles in repair after brain injury. We also introduce a family of proteins known as ADAMs (a disintegrin and metalloproteinase), as some of the properties previously ascribed to MMPs are possibly the result of ADAM activity.

Detection of human influence on twentieth-century precipitation trends

Abstract: Human influence on climate has been detected in surface air temperature, sea level pressure, free atmospheric temperature, tropopause height and ocean heat content. Human-induced changes have not, however, previously been detected in precipitation at the global scale, partly because changes in precipitation in different regions cancel each other out and thereby reduce the strength of the global average signal. Models suggest that anthropogenic forcing should have caused a small increase in global mean precipitation and a latitudinal redistribution of precipitation, increasing precipitation at high latitudes, decreasing precipitation at sub-tropical latitudes, and possibly changing the distribution of precipitation within the tropics by shifting the position of the Intertropical Convergence Zone. Here we compare observed changes in land precipitation during the twentieth century averaged over latitudinal bands with changes simulated by fourteen climate models. We show that anthropogenic forcing has had a detectable influence on observed changes in average precipitation within latitudinal bands, and that these changes cannot be explained by internal climate variability or natural forcing. We estimate that anthropogenic forcing contributed significantly to observed increases in precipitation in the Northern Hemisphere mid-latitudes, drying in the Northern Hemisphere subtropics and tropics, and moistening in the Southern Hemisphere subtropics and deep tropics. The observed changes, which are larger than estimated from model simulations, may have already had significant effects on ecosystems, agriculture and human health in regions that are sensitive to changes in precipitation, such as the Sahel.

Quantifying the biodiversity value of tropical primary, secondary, and plantation forests.

Abstract: Biodiversity loss from deforestation may be partly offset by the expansion of secondary forests and plantation forestry in the tropics. However, our current knowledge of the value of these habitats for biodiversity conservation is limited to very few taxa, and many studies are severely confounded by methodological shortcomings. We examined the conservation value of tropical primary, secondary, and plantation forests for 15 taxonomic groups using a robust and replicated sample design that minimized edge effects. Different taxa varied markedly in their response to patterns of land use in terms of species richness and the percentage of species restricted to primary forest (varying from 5% to 57%), yet almost all between-forest comparisons showed marked differences in community structure and composition. Cross-taxon congruence in response patterns was very weak when evaluated using abundance or species richness data, but much stronger when using metrics based upon community similarity. Our results show that, whereas the biodiversity indicator group concept may hold some validity for several taxa that are frequently sampled (such as birds and fruit-feeding butterflies), it fails for those exhibiting highly idiosyncratic responses to tropical land-use change (including highly vagile species groups such as bats and orchid bees), highlighting the problems associated with quantifying the biodiversity value of anthropogenic habitats. Finally, although we show that areas of native regeneration and exotic tree plantations can provide complementary conservation services, we also provide clear empirical evidence demonstrating the irreplaceable value of primary forests.

Climate over past millennia

Abstract: [1] We review evidence for climate change over the past several millennia from instrumental and high-resolution climate “proxy” data sources and climate modeling studies. We focus on changes over the past 1 to 2 millennia. We assess reconstructions and modeling studies analyzing a number of different climate fields, including atmospheric circulation diagnostics, precipitation, and drought. We devote particular attention to proxy-based reconstructions of temperature patterns in past centuries, which place recent large-scale warming in an appropriate longer-term context. Our assessment affirms the conclusion that late 20th century warmth is unprecedented at hemispheric and, likely, global scales. There is more tentative evidence that particular modes of climate variability, such as the El Nino/Southern Oscillation and the North Atlantic Oscillation, may have exhibited late 20th century behavior that is anomalous in a long-term context. Regional conclusions, particularly for the Southern Hemisphere and parts of the tropics where high-resolution proxy data are sparse, are more circumspect. The dramatic differences between regional and hemispheric/global past trends, and the distinction between changes in surface temperature and precipitation/drought fields, underscore the limited utility in the use of terms such as the “Little Ice Age” and “Medieval Warm Period” for describing past climate epochs during the last millennium. Comparison of empirical evidence with proxy-based reconstructions demonstrates that natural factors appear to explain relatively well the major surface temperature changes of the past millennium through the 19th century (including hemispheric means and some spatial patterns). Only anthropogenic forcing of climate, however, can explain the recent anomalous warming in the late 20th century.