University of Electronic Science and Technology of China

About: University of Electronic Science and Technology of China is a education organization based out in Chengdu, China. It is known for research contribution in the topics: Antenna (radio) & Dielectric. The organization has 50594 authors who have published 58502 publications receiving 711188 citations. The organization is also known as: UESTC.

Frequency-Selective Rasorber Based on Square-Loop and Cross-Dipole Arrays

Abstract: A novel design of a transmission window within the absorption band of a circuit analog absorber, named as frequency-selective rasorber (FSR), is presented. Based on an equivalent circuit model, the conditions are formulated to produce a passband with small insertion loss and to reduce the reflection at frequencies below and above the passband in the meanwhile. Simple design guidelines of our proposed FSR are then developed. With loaded lumped elements, the arrays of square-loop and cross-dipole are combined to realize its implementation. It is shown through measurements that an insertion loss of 0.68 dB can be obtained at 4.42 GHz and the fractional bandwidth for at least 10 dB reflection reduction within the lower and upper frequency bands is 92.3% under the normal incidence. A good agreement between simulated and measured results validates our design.

Recent advances in the development of protein-protein interactions modulators: mechanisms and clinical trials.

Abstract: Protein–protein interactions (PPIs) have pivotal roles in life processes. The studies showed that aberrant PPIs are associated with various diseases, including cancer, infectious diseases, and neurodegenerative diseases. Therefore, targeting PPIs is a direction in treating diseases and an essential strategy for the development of new drugs. In the past few decades, the modulation of PPIs has been recognized as one of the most challenging drug discovery tasks. In recent years, some PPIs modulators have entered clinical studies, some of which been approved for marketing, indicating that the modulators targeting PPIs have broad prospects. Here, we summarize the recent advances in PPIs modulators, including small molecules, peptides, and antibodies, hoping to provide some guidance to the design of novel drugs targeting PPIs in the future.

Default mode network abnormalities in mesial temporal lobe epilepsy: a study combining fMRI and DTI.

Abstract: Studies of in mesial temporal lobe epilepsy (mTLE) patients with hippocampal sclerosis (HS) have reported reductions in both functional and structural connectivity between hippocampal structures and adjacent brain regions. However, little is known about the connectivity among the default mode network (DMN) in mTLE. Here, we hypothesized that both functional and structural connectivity within the DMN were disturbed in mTLE. To test this hypothesis, functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) were applied to examine the DMN connectivity of 20 mTLE patients, and 20 gender- and age-matched healthy controls. Combining these two techniques, we explored the changes in functional (temporal correlation coefficient derived from fMRI) and structural (path length and connection density derived from DTI tractography) connectivity of the DMN. Compared to the controls, we found that both functional and structural connectivity were significantly decreased between the posterior cingulate cortex (PCC)/precuneus (PCUN) and bilateral mesial temporal lobes (mTLs) in patients. No significant between-group difference was found between the PCC/PCUN and medial prefrontal cortex (mPFC). In addition, functional connectivity was found to be correlated with structural connectivity in two pairwise regions, namely between the PCC/PCUN and bilateral mTLs, respectively. Our results suggest that the decreased functional connectivity within the DMN in mTLE may be a consequence of the decreased connection density underpinning the degeneration of structural connectivity.

Deep Reinforcement Learning for User Association and Resource Allocation in Heterogeneous Cellular Networks

Abstract: Heterogeneous cellular networks can offload the mobile traffic and reduce the deployment costs, which have been considered to be a promising technique in the next-generation wireless network. Due to the non-convex and combinatorial characteristics, it is challenging to obtain an optimal strategy for the joint user association and resource allocation issue. In this paper, a reinforcement learning (RL) approach is proposed to achieve the maximum long-term overall network utility while guaranteeing the quality of service requirements of user equipments (UEs) in the downlink of heterogeneous cellular networks. A distributed optimization method based on multi-agent RL is developed. Moreover, to solve the computationally expensive problem with the large action space, multi-agent deep RL method is proposed. Specifically, the state, action and reward function are defined for UEs, and dueling double deep Q-network (D3QN) strategy is introduced to obtain the nearly optimal policy. Through message passing, the distributed UEs can obtain the global state space with a small communication overhead. With the double-Q strategy and dueling architecture, D3QN can rapidly converge to a subgame perfect Nash equilibrium. Simulation results demonstrate that D3QN achieves the better performance than other RL approaches in solving large-scale learning problems.