Institution
University of Erlangen-Nuremberg
Education•Erlangen, Bayern, Germany•
About: University of Erlangen-Nuremberg is a education organization based out in Erlangen, Bayern, Germany. It is known for research contribution in the topics: Population & Immune system. The organization has 42405 authors who have published 85600 publications receiving 2663922 citations.
Topics: Population, Immune system, Catalysis, Medicine, Computer science
Papers published on a yearly basis
Papers
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University of Bern1, University of Toronto2, Niigata University3, University of Lausanne4, Pierre-and-Marie-Curie University5, Copenhagen University Hospital6, University of Erlangen-Nuremberg7, University of California, San Francisco8, Medical University of Graz9, Radboud University Nijmegen10, Geneva College11, University of Helsinki12, University College Dublin13, Mayo Clinic14, Tokyo Medical and Dental University15, Paris Descartes University16, National Defense Medical College17, St James's University Hospital18
TL;DR: Members of the ITBCC were able to reach strong consensus on a single international, evidence-based method for tumor budding assessment and reporting and it is proposed that this method be incorporated into colorectal cancer guidelines/protocols and staging systems.
595 citations
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TL;DR: Optical coherence tomography angiography, generated by the new SSADA, repeatably measures optic disc perfusion and may be useful in the evaluation of glaucoma and glAUcoma progression.
595 citations
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Queen Mary University of London1, University of Bath2, University of Leeds3, Bocconi University4, London School of Economics and Political Science5, European Society of Cardiology6, Intermountain Medical Center7, Ghent University8, University of East Anglia9, University of Cape Town10, University of Adelaide11, Leipzig University12, Leiden University Medical Center13, John Radcliffe Hospital14, University of Erlangen-Nuremberg15, University of Oxford16
TL;DR: A seemingly inexorable rise in the prevalence of obesity and diabetes currently provides the greatest challenge to achieving further reductions in CVD burden across ESC member countries.
Abstract: Aims: The 2019 report from the European Society of Cardiology (ESC) Atlas provides a contemporary analysis of cardiovascular disease (CVD) statistics across 56 member countries, with particular emphasis on international inequalities in disease burden and healthcare delivery together with estimates of progress towards meeting 2025 World Health Organization (WHO) non-communicable disease targets.
Methods and results: In this report, contemporary CVD statistics are presented for member countries of the ESC. The statistics are drawn from the ESC Atlas which is a repository of CVD data from a variety of sources including the WHO, the Institute for Health Metrics and Evaluation, and the World Bank. The Atlas also includes novel ESC sponsored data on human and capital infrastructure and cardiovascular healthcare delivery obtained by annual survey of the national societies of ESC member countries. Across ESC member countries, the prevalence of obesity (body mass index >= 30 kg/m(2)) and diabetes has increased two- to three-fold during the last 30years making the WHO 2025 target to halt rises in these risk factors unlikely to be achieved. More encouraging have been variable declines in hypertension, smoking, and alcohol consumption but on current trends only the reduction in smoking from 28% to 21% during the last 20years appears sufficient for the WHO target to be achieved. The median age-standardized prevalence of major risk factors was higher in middle-income compared with high-income ESC member countries for hypertension {23.8% [interquartile range (IQR) 22.5-23.1%] vs. 15.7% (IQR 14.5-21.1%)}, diabetes [7.7% (IQR 7.1-10.1%) vs. 5.6% (IQR 4.8-7.0%)], and among males smoking [43.8% (IQR 37.4-48.0%) vs. 26.0% (IQR 20.9-31.7%)] although among females smoking was less common in middle-income countries [8.7% (IQR 3.0-10.8) vs. 16.7% (IQR 13.9-19.7%)]. There were associated inequalities in disease burden with disability-adjusted life years per 100 000 people due to CVD over three times as high in middle-income [7160 (IQR 5655-8115)] compared with high-income [2235 (IQR 1896-3602)] countries. Cardiovascular disease mortality was also higher in middle-income countries where it accounted for a greater proportion of potential years of life lost compared with high-income countries in both females (43% vs. 28%) and males (39% vs. 28%). Despite the inequalities in disease burden across ESC member countries, survey data from the National Cardiac Societies of the ESC showed that middle-income member countries remain severely under-resourced compared with high-income countries in terms of cardiological person-power and technological infrastructure. Under-resourcing in middle-income countries is associated with a severe procedural deficit compared with high-income countries in terms of coronary intervention, device implantation and cardiac surgical procedures.
Conclusion: A seemingly inexorable rise in the prevalence of obesity and diabetes currently provides the greatest challenge to achieving further reductions in CVD burden across ESC member countries. Additional challenges are provided by inequalities in disease burden that now require intensification of policy initiatives in order to reduce population risk and prioritize cardiovascular healthcare delivery, particularly in the middle-income countries of the ESC where need is greatest.
591 citations
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TL;DR: Tomlinson-Harashima Precoding for multiple-input/multiple-output systems including multiple-antenna and multiuser systems is studied and it is shown that nonlinear preequalization offers significant advantages over linear preeQualization which increases average transmit power.
Abstract: In this paper, Tomlinson-Harashima Precoding for multiple-input/multiple-output systems including multiple-antenna and multiuser systems is studied. It is shown that nonlinear preequalization offers significant advantages over linear preequalization which increases average transmit power. Moreover, it outperforms decision-feedback equalization at the receiver side which is applicable if joint processing at the receiver side is possible, and which suffers from error propagation. A number of aspects of practical importance are studied. Loading, i.e., the optimum distribution of transmit power and rate is discussed in detail. It is shown that the capacity of the underlying MIMO channel can be utilized asymptotically by means of nonlinear precoding.
590 citations
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Leipzig University1, University of Jena2, University of Münster3, Martin Luther University of Halle-Wittenberg4, University of Greifswald5, Heidelberg University6, Augsburg College7, University of Erlangen-Nuremberg8, University of Giessen9, Charité10, University of Göttingen11, Dresden University of Technology12, RWTH Aachen University13, University of Bonn14, University of Kiel15, Hannover Medical School16
TL;DR: The expected number of newly diagnosed cases with severe sepsis in Germany amounts to 76–110 per 100,000 adult inhabitants and future epidemiological studies should use standardized study methodologies with respect to sepsi definitions, hospital size, and daily and monthly variability.
Abstract: To determine the prevalence and mortality of ICU patients with severe sepsis in Germany, with consideration of hospital size. Prospective, observational, cross-sectional 1-day point-prevalence study. 454 ICUs from a representative nationwide sample of 310 hospitals stratified by size. Data were collected via 1-day on-site audits by trained external study physicians. Visits were randomly distributed over 1 year (2003). Inflammatory response of all ICU patients was assessed using the ACCP/SCCM consensus conference criteria. Patients with severe sepsis were followed up after 3 months for hospital mortality and length of ICU stay. Main outcome measures were prevalence and mortality. A total of 3,877 patients were screened. Prevalence was 12.4% (95% CI, 10.9–13.8%) for sepsis and 11.0% (95% CI, 9.7–12.2%) for severe sepsis including septic shock. The ICU and hospital mortality of patients with severe sepsis was 48.4 and 55.2%, respectively, without significant differences between hospital size. Prevalence and mean length of ICU stay of patients with severe sepsis were significantly higher in larger hospitals and universities (≤ 200 beds: 6% and 11.5 days, universities: 19% and 19.2 days, respectively). The expected number of newly diagnosed cases with severe sepsis in Germany amounts to 76–110 per 100,000 adult inhabitants. To allow better comparison between countries, future epidemiological studies should use standardized study methodologies with respect to sepsis definitions, hospital size, and daily and monthly variability.
589 citations
Authors
Showing all 42831 results
Name | H-index | Papers | Citations |
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Hermann Brenner | 151 | 1765 | 145655 |
Richard B. Devereux | 144 | 962 | 116403 |
Manfred Paulini | 141 | 1791 | 110930 |
Daniel S. Berman | 141 | 1363 | 86136 |
Peter Lang | 140 | 1136 | 98592 |
Joseph Sodroski | 138 | 542 | 77070 |
Richard J. Johnson | 137 | 880 | 72201 |
Jun Lu | 135 | 1526 | 99767 |
Michael Schmitt | 134 | 2007 | 114667 |
Jost B. Jonas | 132 | 1158 | 166510 |
Andreas Mussgiller | 127 | 1059 | 73778 |
Matthew J. Budoff | 125 | 1449 | 68115 |
Stefan Funk | 125 | 506 | 56955 |
Markus F. Neurath | 124 | 934 | 62376 |
Jean-Marie Lehn | 123 | 1054 | 84616 |