University of Exeter

About: University of Exeter is a education organization based out in Exeter, United Kingdom. It is known for research contribution in the topics: Population & Climate change. The organization has 15820 authors who have published 50650 publications receiving 1793046 citations. The organization is also known as: Exeter University & University of the South West of England.

The evolutionary origins of pesticide resistance.

Abstract: Durable crop protection is an essential component of current and future food security. However, the effectiveness of pesticides is threatened by the evolution of resistant pathogens, weeds and insect pests. Pesticides are mostly novel synthetic compounds, and yet target species are often able to evolve resistance soon after a new compound is introduced. Therefore, pesticide resistance provides an interesting case of rapid evolution under strong selective pressures, which can be used to address fundamental questions concerning the evolutionary origins of adaptations to novel conditions. We ask: (i) whether this adaptive potential originates mainly from de novo mutations or from standing variation; (ii) which pre-existing traits could form the basis of resistance adaptations; and (iii) whether recurrence of resistance mechanisms among species results from interbreeding and horizontal gene transfer or from independent parallel evolution. We compare and contrast the three major pesticide groups: insecticides, herbicides and fungicides. Whilst resistance to these three agrochemical classes is to some extent united by the common evolutionary forces at play, there are also important differences. Fungicide resistance appears to evolve, in most cases, by de novo point mutations in the target-site encoding genes; herbicide resistance often evolves through selection of polygenic metabolic resistance from standing variation; and insecticide resistance evolves through a combination of standing variation and de novo mutations in the target site or major metabolic resistance genes. This has practical implications for resistance risk assessment and management, and lessons learnt from pesticide resistance should be applied in the deployment of novel, non-chemical pest-control methods.

Embodiment, academics, and the audit culture: a story seeking consideration

Abstract: In response to the plea by Pelias (2004) for a methodology of the heart, this article presents a story about the embodied struggles of an academic at a university that is permeated by an audit culture. It is based on informal interviews with academics at various universities in England and selected personal experiences. Thus, the constructive process is inspired by partial happenings, fragmented memories, echoes of conversations, whispers in corridors, fleeting glimpses of myriad reflections seen through broken glass, and multiple layers of fiction and narrative imaginings. Methodological issues abound in the telling and showing but, quite rightly, remain dormant on this occasion. In the end, the story simply asks for your consideration.

Identity-Based Remote Data Integrity Checking With Perfect Data Privacy Preserving for Cloud Storage

Abstract: Remote data integrity checking (RDIC) enables a data storage server, say a cloud server, to prove to a verifier that it is actually storing a data owner’s data honestly. To date, a number of RDIC protocols have been proposed in the literature, but most of the constructions suffer from the issue of a complex key management, that is, they rely on the expensive public key infrastructure (PKI), which might hinder the deployment of RDIC in practice. In this paper, we propose a new construction of identity-based (ID-based) RDIC protocol by making use of key-homomorphic cryptographic primitive to reduce the system complexity and the cost for establishing and managing the public key authentication framework in PKI-based RDIC schemes. We formalize ID-based RDIC and its security model, including security against a malicious cloud server and zero knowledge privacy against a third party verifier. The proposed ID-based RDIC protocol leaks no information of the stored data to the verifier during the RDIC process. The new construction is proven secure against the malicious server in the generic group model and achieves zero knowledge privacy against a verifier. Extensive security analysis and implementation results demonstrate that the proposed protocol is provably secure and practical in the real-world applications.

Exploring links between Arctic amplification and mid‐latitude weather

Abstract: This study examines observed changes (1979-2011) in atmospheric planetary-wave amplitude over northern mid-latitudes, which have been proposed as a possible mechanism linking Arctic amplification and mid-latitude weather extremes. We use two distinct but equally-valid definitions of planetary-wave amplitude, termed meridional amplitude, a measure of north-south meandering, and zonal amplitude, a measure of the intensity of atmospheric ridges and troughs at 45°N. Statistically significant changes in either metric are limited to few seasons, wavelengths, and longitudinal sectors. However in summer, we identify significant increases in meridional amplitude over Europe, but significant decreases in zonal amplitude hemispherically, and also individually over Europe and Asia. Therefore, we argue that possible connections between Arctic amplification and planetary waves, and implications of these, are sensitive to how waves are conceptualized. The contrasting meridional and zonal amplitude trends have different and complex possible implications for midlatitude weather, and we encourage further work to better understand these. © 2013. American Geophysical Union. All Rights Reserved.

The efficacy of ginseng. A systematic review of randomised clinical trials.

Abstract: Objective: Ginseng is one of the most popular herbal remedies, and a number of health claims are made for it. This systematic review provides an evaluation of the current evidence for or against the efficacy of ginseng root extract. Methods: Searches of the computerised literature databases Medline, Embase, Biosis, CISCOM and the Cochrane Library were performed to retrieve double-blind, randomised, placebo-controlled trials of ginseng root extract for any indication. Manufacturers and experts were contacted to provide additional information. There were no restrictions regarding the language of publication. The outcome and methodological quality of all trials were independently assessed by two reviewers. Results: Sixteen trials met the inclusion criteria and were reviewed. These trials related to physical performance, psychomotor performance and cognitive function, immunmodulation, diabetes mellitus and herpes simplex type-II infections. The evidence found for ginseng root extract is compelling for none of these indications. Conclusion: Based on these data, it is concluded that the efficacy of ginseng root extract is not established beyond reasonable doubt for any of these indications. The widespread use of ginseng as a herbal remedy warrants more rigorous investigations to assess its efficacy and safety.