Institution
University of Exeter
Education•Exeter, United Kingdom•
About: University of Exeter is a education organization based out in Exeter, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 15820 authors who have published 50650 publications receiving 1793046 citations. The organization is also known as: Exeter University & University of the South West of England.
Papers published on a yearly basis
Papers
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TL;DR: In this article, the reliability of many load estimates, particularly those for substances where particulate-associated transport predominates, is questioned, and a case study of the accuracy and precision of estimates of the suspended sediment load of the River Exe at Thorverton for the period 1978-1980 is used to demonstrate the potential reliability of loads calculated using a variety of estimation procedures.
333 citations
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TL;DR: The solvothermal method has recently been extended from zeolite synthesis to the formation of condensed inorganic solids, which find uses in diverse areas due to properties such as ionic-conductivity, solid-state magnetism, giant magnetoresistance, low thermal expansion and ferroelectricity.
Abstract: The solvothermal method has recently been extended from zeolite synthesis to the formation of condensed inorganic solids, which find uses in diverse areas due to properties such as ionic-conductivity, solid-state magnetism, giant magnetoresistance, low thermal expansion and ferroelectricity. This offers specific advantages over the traditional ceramic synthetic routes to inorganic solids and these are highlighted with examples from the recent literature, and the efforts focussed on determining the formation mechanism of solids from the heterogeneous mixtures used in solvothermal procedures are discussed.
332 citations
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Marcel den Hoed1, Mark Eijgelsheim2, Tõnu Esko3, Bianca J. J. M. Brundel4 +264 more•Institutions (85)
TL;DR: A 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci, providing fresh insights into the mechanisms regulating heart rate.
Abstract: Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci. Experimental downregulation of gene expression in Drosophila melanogaster and Danio rerio identified 20 genes at 11 loci that are relevant for heart rate regulation and highlight a role for genes involved in signal transmission, embryonic cardiac development and the pathophysiology of dilated cardiomyopathy, congenital heart failure and/or sudden cardiac death. In addition, genetic susceptibility to increased heart rate is associated with altered cardiac conduction and reduced risk of sick sinus syndrome, and both heart rate-increasing and heart rate-decreasing variants associate with risk of atrial fibrillation. Our findings provide fresh insights into the mechanisms regulating heart rate and identify new therapeutic targets.
332 citations
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University of Reading1, Leipzig University2, Imperial College London3, Max Planck Society4, University of Oxford5, University of Paris6, University of Leeds7, University of Bordeaux8, École Normale Supérieure9, National Oceanic and Atmospheric Administration10, University of Cologne11, National Center for Atmospheric Research12, University of Exeter13, Met Office14, ETH Zurich15, Stockholm University16, University of Oslo17, Carnegie Institution for Science18, Goethe University Frankfurt19, Nagoya University20, Hokkaido University21, Norwegian Meteorological Institute22, Brookhaven National Laboratory23, Lille University of Science and Technology24, University of Tartu25, Langley Research Center26
TL;DR: A new range of aerosol radiative forcing over the industrial era is provided based on multiple, traceable, and arguable lines of evidence, including modeling approaches, theoretical considerations, and observations, to constrain the forcing from aerosol‐radiation interactions.
Abstract: Aerosols interact with radiation and clouds. Substantial progress made over the past 40 years in observing, understanding, and modeling these processes helped quantify the imbalance in the Earth’s radiation budget caused by anthropogenic aerosols, called aerosol radiative forcing, but uncertainties remain large. This review provides a new range of aerosol radiative forcing over the industrial era based on multiple, traceable and arguable lines of evidence, including modelling approaches, theoretical considerations, and observations. Improved understanding of aerosol absorption and the causes of trends in surface radiative fluxes constrain the forcing from aerosol-radiation interactions. A robust theoretical foundation and convincing evidence constrain the forcing caused by aerosol-driven increases in liquid cloud droplet number concentration. However, the influence of anthropogenic aerosols on cloud liquid water content and cloud fraction is less clear, and the influence on mixed-phase and ice clouds remains poorly constrained. Observed changes in surface temperature and radiative fluxes provide additional constraints. These multiple lines of evidence lead to a 68% confidence interval for the total aerosol effective radiative forcing of −1.60 to −0.65 W m−2, or −2.0 to −0.4 W m−2 with a 90% likelihood. Those intervals are of similar width to the last Intergovernmental Panel on Climate Change assessment but shifted towards more negative values. The uncertainty will narrow in the future by continuing to critically combine multiple lines of evidence, especially those addressing industrial-era changes in aerosol sources and aerosol effects on liquid cloud amount and on ice clouds.
332 citations
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TL;DR: The degree to which students in the intervention group practised the mindfulness skills was associated with better well-being and less stress, and this provides promising evidence of the programme's acceptability and efficacy.
Abstract: Background
Mindfulness-based approaches for adults are effective at enhancing mental health, but few controlled trials have evaluated their effectiveness among young people.
Aims
To assess the acceptability and efficacy of a schools-based universal mindfulness intervention to enhance mental health and well-being.
Method
A total of 522 young people aged 12-16 in 12 secondary schools either participated in the Mindfulness in Schools Programme (intervention) or took part in the usual school curriculum (control).
Results
Rates of acceptability were high. Relative to the controls, and after adjusting for baseline imbalances, children who participated in the intervention reported fewer depressive symptoms post-treatment ( P = 0.004) and at follow-up ( P = 0.005) and lower stress ( P = 0.05) and greater well-being ( P = 0.05) at follow-up. The degree to which students in the intervention group practised the mindfulness skills was associated with better well-being ( P <0.001) and less stress ( P = 0.03) at 3-month follow-up.
Conclusions
The findings provide promising evidence of the programme’s acceptability and efficacy.
332 citations
Authors
Showing all 16338 results
Name | H-index | Papers | Citations |
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Frank B. Hu | 250 | 1675 | 253464 |
John C. Morris | 183 | 1441 | 168413 |
David W. Johnson | 160 | 2714 | 140778 |
Kevin J. Gaston | 150 | 750 | 85635 |
Andrew T. Hattersley | 146 | 768 | 106949 |
Timothy M. Frayling | 133 | 500 | 100344 |
Joel N. Hirschhorn | 133 | 431 | 101061 |
Jonathan D. G. Jones | 129 | 417 | 80908 |
Graeme I. Bell | 127 | 531 | 61011 |
Mark D. Griffiths | 124 | 1238 | 61335 |
Tao Zhang | 123 | 2772 | 83866 |
Brinick Simmons | 122 | 691 | 69350 |
Edzard Ernst | 120 | 1326 | 55266 |
Michael Stumvoll | 119 | 655 | 69891 |
Peter McGuffin | 117 | 624 | 62968 |