Institution
University of Exeter
Education•Exeter, United Kingdom•
About: University of Exeter is a education organization based out in Exeter, United Kingdom. It is known for research contribution in the topics: Population & Climate change. The organization has 15820 authors who have published 50650 publications receiving 1793046 citations. The organization is also known as: Exeter University & University of the South West of England.
Papers published on a yearly basis
Papers
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TL;DR: The reduced O2 cost of exercise following increased dietary nitrate intake has important implications for the understanding of the factors that regulate mitochondrial respiration and muscle contractile energetics in humans.
Abstract: Pharmacological sodium nitrate supplementation has been reported to reduce the O2 cost of submaximal exercise in humans. In this study, we hypothesized that dietary supplementation with inorganic n...
678 citations
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University College London1, International Institute for Applied Systems Analysis2, United Nations University3, University of London4, World Bank5, University of Colorado Boulder6, Umeå University7, Tsinghua University8, World Health Organization9, University of Exeter10, University of Birmingham11, Royal Veterinary College12, University of Washington13, International Livestock Research Institute14, University of York15, Cayetano Heredia University16, University of Sussex17, University of Arkansas at Monticello18, University of Essex19, Baqiyatallah University of Medical Sciences20, Iran University of Medical Sciences21, Imperial College London22, University of Reading23, World Meteorological Organization24
TL;DR: The Lancet Countdown track progress on health and climate change and provides an independent assessment of the health effects of climate change, the implementation of the Paris Agreement, 1 and 3.
676 citations
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TL;DR: It is apparent that the chalcogen amino acids cysteine, methionine, selenocysteines, and selenomethionine exhibit a unique biological chemistry that is the source of exciting research opportunities.
Abstract: Sulfur and selenium occur in proteins as constituents of the amino acids cysteine, methionine, selenocysteine, and selenomethionine. Recent research underscores that these amino acids are truly exceptional. Their redox activity under physiological conditions allows an amazing variety of posttranslational protein modifications, metal free redox pathways, and unusual chalcogen redox states that increasingly attract the attention of biological chemists. Unlike any other amino acid, the "redox chameleon" cysteine can participate in several distinct redox pathways, including exchange and radical reactions, as well as atom-, electron-, and hydride-transfer reactions. It occurs in various oxidation states in the human body, each of which exhibits distinctive chemical properties (e.g. redox activity, metal binding) and biological activity. The position of selenium in the periodic table between the metals and the nonmetals makes selenoproteins ideal catalysts for many biological redox transformations. It is therefore apparent that the chalcogen amino acids cysteine, methionine, selenocysteine, and selenomethionine exhibit a unique biological chemistry that is the source of exciting research opportunities.
674 citations
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TL;DR: Observations of hundreds of pests and pathogens reveal an average poleward shift of 2.7±0.8 km yr−1 since 1960, supporting the hypothesis of climate-driven pest movement.
Abstract: The extent to which crop pests and pathogens have altered their latitudinal ranges in response to climate change remains largely unknown. Now observations of hundreds of pests and pathogens reveal an average poleward shift of 2.7±0.8 km yr−1 since 1960, supporting the hypothesis of climate-driven pest movement.
672 citations
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Hammersmith Hospital1, Imperial College London2, Cancer Research UK3, University College London4, Royal North Shore Hospital5, Flinders University6, Monash University7, Ain Shams University8, French Institute of Health and Medical Research9, Charité10, University of Oldenburg11, Magna Græcia University12, Catholic University of the Sacred Heart13, University of Verona14, Tokyo Medical University15, Aichi Medical University16, King Abdulaziz Medical City17, Seoul National University Hospital18, Keimyung University19, University of Ulsan20, Inje University21, Universidad Francisco de Vitoria22, University of Amsterdam23, VU University Amsterdam24, Istanbul University25, University of Florence26, Conquest Hospital27, University of Exeter28, Anglia Ruskin University29, Emory University30, United States Department of Veterans Affairs31, University of Washington32, Stony Brook University33, Canterbury Christ Church University34, Duke University35, Complutense University of Madrid36, Hospital Clínico San Carlos37
TL;DR: Coronary revascularization guided by iFR was noninferior to revascularizations guided by FFR with respect to the risk of major adverse cardiac events at 1 year.
Abstract: BackgroundCoronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone. It is unknown whether the instantaneous wave-free ratio (iFR), an alternative measure that does not require the administration of adenosine, will offer benefits similar to those of FFR. MethodsWe randomly assigned 2492 patients with coronary artery disease, in a 1:1 ratio, to undergo either iFR-guided or FFR-guided coronary revascularization. The primary end point was the 1-year risk of major adverse cardiac events, which were a composite of death from any cause, nonfatal myocardial infarction, or unplanned revascularization. The trial was designed to show the noninferiority of iFR to FFR, with a margin of 3.4 percentage points for the difference in risk. ResultsAt 1 year, the primary end point had occurred in 78 of 1148 patients (6.8%) in the iFR group and in 83 of 1182 patients (7.0%) in the FFR group (difference i...
672 citations
Authors
Showing all 16338 results
Name | H-index | Papers | Citations |
---|---|---|---|
Frank B. Hu | 250 | 1675 | 253464 |
John C. Morris | 183 | 1441 | 168413 |
David W. Johnson | 160 | 2714 | 140778 |
Kevin J. Gaston | 150 | 750 | 85635 |
Andrew T. Hattersley | 146 | 768 | 106949 |
Timothy M. Frayling | 133 | 500 | 100344 |
Joel N. Hirschhorn | 133 | 431 | 101061 |
Jonathan D. G. Jones | 129 | 417 | 80908 |
Graeme I. Bell | 127 | 531 | 61011 |
Mark D. Griffiths | 124 | 1238 | 61335 |
Tao Zhang | 123 | 2772 | 83866 |
Brinick Simmons | 122 | 691 | 69350 |
Edzard Ernst | 120 | 1326 | 55266 |
Michael Stumvoll | 119 | 655 | 69891 |
Peter McGuffin | 117 | 624 | 62968 |