Institution
University of Extremadura
Education•Badajoz, Spain•
About: University of Extremadura is a education organization based out in Badajoz, Spain. It is known for research contribution in the topics: Population & Hyperspectral imaging. The organization has 7856 authors who have published 18299 publications receiving 396126 citations. The organization is also known as: Universidad de Extremadura.
Papers published on a yearly basis
Papers
More filters
TL;DR: Methods for fractional PID controller tuning, including auto-tuning, and some software and hardware strategies for efficient implementations of controllers in industrial applications are presented.
Abstract: In recent years the increasing amount of work related to the application of Fractional Calculus (FC) is remarkable in many areas of science and engineering. In relation to automatic control, the us...
172 citations
TL;DR: The improvement in the decomposition levels of carbofuran reached by the combined processes in relation to the single oxidants, due to the generation of the very reactive hydroxyl radicals, is also established in every process.
172 citations
TL;DR: The hypothesis that receptor–ligand crosslinking downregulates DNAM‐1 expression on NK cells from patients <65 years of age is supported and can represent an additional mechanism of tumor escape.
Abstract: This study tested the hypothesis that the expression of CD112 and CD155 (DNAM-1 ligands) on leukemic blasts induces a decreased expression of the activating receptor DNAM-1 on natural killer (NK) cells from acute myeloid leukemia (AML) patients. DNAM-1 is a co-receptor involved in the activation of NK cell cytotoxicity after its interaction with its ligands CD112 and CD155 on target cells. Here we study the expression of DNAM-1 on NK cells and DNAM-1 ligands on blasts from AML patients stratified by age. The results demonstrate that NK cells from AML patients younger than 65 years have a reduced expression of DNAM-1 compared with age-matched controls. The analysis of DNAM-1 ligands showed a high expression of CD112 and CD155 on leukemic blasts. An inverse correlation between CD112 expression on leukemic blasts and DNAM-1 expression on NK cells was found. Furthermore, downregulation of DNAM-1 was induced on healthy donors' NK cells after in vitro culture with leukemic blasts expressing DNAM-1 ligands. In conclusion, these results support the hypothesis that receptor-ligand crosslinking downregulates DNAM-1 expression on NK cells from patients <65 years of age. Considering the relevance of DNAM-1 in NK recognition and killing of leukemic cells, the reduced expression of this receptor on NK cells from AML patients can represent an additional mechanism of tumor escape.
172 citations
TL;DR: In this paper, the authors evaluated the effectiveness of peel and seed extracts from two avocado varieties, Hass and Fuerte, as inhibitors of lipid and protein oxidation and color deterioration of raw porcine patties during chilled storage (4 °C/15 days).
171 citations
TL;DR: Permanganate oxidation is a feasible option for microcystin removal during preoxidation processes, however, the oxidant dose must be carefully optimized in order to remove extracellular MCs without causing cell lysis and further release of MCs.
171 citations
Authors
Showing all 8001 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Russel J. Reiter | 169 | 1646 | 121010 |
| Donald G. Truhlar | 165 | 1518 | 157965 |
| Manel Esteller | 146 | 713 | 96429 |
| David J. Williams | 107 | 2060 | 62440 |
| Keijo Häkkinen | 99 | 421 | 31355 |
| Robert H. Anderson | 97 | 1237 | 41250 |
| Leif Bertilsson | 87 | 321 | 23933 |
| Mario F. Fraga | 84 | 267 | 32957 |
| YangQuan Chen | 84 | 1048 | 36543 |
| Antonio Plaza | 79 | 631 | 29775 |
| Robert D. Gibbons | 75 | 349 | 26330 |
| Jocelyn Chanussot | 73 | 614 | 27949 |
| Naresh Magan | 72 | 400 | 17511 |
| Luis Puelles | 71 | 269 | 19858 |
| Jun Li | 70 | 799 | 19510 |