Institution
University of Fribourg
Education•Fribourg, Freiburg, Switzerland•
About: University of Fribourg is a education organization based out in Fribourg, Freiburg, Switzerland. It is known for research contribution in the topics: Population & Glacier. The organization has 6040 authors who have published 14975 publications receiving 542500 citations. The organization is also known as: UNIFR & Universität Freiburg.
Topics: Population, Glacier, Excited state, Hubbard model, Scattering
Papers published on a yearly basis
Papers
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TL;DR: Time-resolved correlation (TRC) as discussed by the authors is a new scheme for investigating temporally heterogeneous dynamics, which is applied to data obtained by diffusing wave spectroscopy probing the slow dynamics of a strongly aggregated colloidal gel.
Abstract: We introduce a new scheme for investigating temporally heterogeneous dynamics, which is termed time-resolved correlation (TRC). TRC is applied to data obtained by diffusing wave spectroscopy probing the slow dynamics of a strongly aggregated colloidal gel. Other examples of TRC data, collected for different jammed materials in single and multiple scattering, are provided to demonstrate the wide range of applicability of this method. In all cases we find evidence that the slow dynamics results from a series of discrete steps rather than from a continuous motion, suggesting temporal heterogeneities to be a general feature of slow dynamics in jammed systems.
160 citations
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TL;DR: It is concluded that Ca2+ buffers with slow kinetics, such as PV, may cause biexponential decays in [Ca2+] transients, thereby complicating the analysis of endogenous Ca2- binding ratios (κS) based on time constants.
Abstract: 1
κS1. The effect of parvalbumin (PV) on [Ca2+] transients was investigated by perfusing adrenal chromaffin cells with fura-2 and fluorescein isothiocyanate (FITC)-labelled PV. As PV diffused into cells, the decay of [Ca2+] transients was transformed from monophasic into biphasic. The proportion of the initial fast decay phase increased in parallel with the fluorescence intensity of FITC, indicating that PV is responsible for the initial fast decay phase.
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The relationship between the fast decay phase and the [Ca2+] level was investigated using depolarizing trains of stimuli. Within a train the relative amplitude of the fast decay phase was inversely dependent on the [Ca2+] level preceding a given stimulus.
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Based on these observations, we estimated the Ca2+ binding ratio of PV (κP), the apparent dissociation constant of PV for Ca2+ (Kdc,app), and the unbinding rate constant of Ca2+ from PV (kc-) in the cytosol of chromaffin cells. Assuming free [Mg2+] to be 0.14 mm, we obtained values of 51.4 ± 2.0 nm (n= 3) and 0.95 ± 0.026 s−1 (n= 3), for Kdc,app and kc-, respectively.
4
With the parameters obtained in the perfusion study, we simulated [Ca2+] transients, using two different Ca2+ extrusion rates (γ) – 20 and 300 s−1– which represent typical values for chromaffin cells and neuronal dendrites, respectively. The simulation indicated that Ca2+ is pumped out before it is equilibrated with PV, when γ is comparable to the equilibration rates between PV and Ca2+, resulting in the fast decay phase of a biexponential [Ca2+] transient.
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From these results we conclude that Ca2+ buffers with slow kinetics, such as PV, may cause biexponential decays in [Ca2+] transients, thereby complicating the analysis of endogenous Ca2+ binding ratios (κS) based on time constants. Nevertheless, estimates of κS based on Ca2+ increments provide reasonable estimates for Ca2+ binding ratios before equilibration with PV.
160 citations
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TL;DR: It is shown that these circadian oscillations depend on circadian modification of dynamin-related protein 1 (DRP1), a key mediator of mitochondrial fission, and genetic or pharmacological abrogation of DRP1 activity abolished circadian network dynamics and mitochondrial respiratory activity and eliminated circadian ATP production.
160 citations
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TL;DR: Testing the effect of farming practices differing in disturbance intensity on the abundance, species richness and community composition of three trophic levels in Swiss vineyards concludes that disturbance in organically farmed vineyards appears to be too low to be beneficial for biodiversity.
160 citations
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TL;DR: In this paper, the authors demonstrate that the scale is applicable for retail brands in Germany, that it serves well to clearly differentiate between retailers and that the dimensions of the brand personality directly influence the store loyalty of consumers.
Abstract: In recent years, marketing research has paid considerable attention to the symbolic meaning consumers attribute to brands. One important symbolic brand association is brand personality. While the brand personality scale that Aaker has proposed in her well-known article has been applied to different products and product groups in different countries, an application to retailing is rare. Based on the data of an empirical study in Germany (n = 1337), we demonstrate that the scale is applicable for retail brands in Germany, that it serves well to clearly differentiate between retailers and that the dimensions of the brand personality directly influence the store loyalty of consumers.
160 citations
Authors
Showing all 6204 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jens Nielsen | 149 | 1752 | 104005 |
Sw. Banerjee | 146 | 1906 | 124364 |
Hans Peter Beck | 143 | 1134 | 91858 |
Patrice Nordmann | 127 | 790 | 67031 |
Abraham Z. Snyder | 125 | 329 | 91997 |
Csaba Szabó | 123 | 958 | 61791 |
Robert Edwards | 121 | 775 | 74552 |
Laurent Poirel | 117 | 621 | 53680 |
Thomas Münzel | 116 | 1055 | 57716 |
David G. Amaral | 112 | 302 | 49094 |
F. Blanc | 107 | 1514 | 58418 |
Markus Stoffel | 102 | 620 | 50796 |
Vincenzo Balzani | 101 | 476 | 45722 |
Enrico Bertini | 99 | 865 | 38167 |
Sandeep Kumar | 94 | 1563 | 38652 |