University of Fribourg

About: University of Fribourg is a education organization based out in Fribourg, Freiburg, Switzerland. It is known for research contribution in the topics: Population & Context (language use). The organization has 6040 authors who have published 14975 publications receiving 542500 citations. The organization is also known as: UNIFR & Universität Freiburg.

Large-scale gene discovery in the oomycete Phytophthora infestans reveals likely components of phytopathogenicity shared with true fungi

Abstract: To overview the gene content of the important pathogen Phytophthora infestans, large-scale cDNA and genomic sequencing was performed. A set of 75,757 high-quality expressed sequence tags (ESTs) from P. infestans was obtained from 20 cDNA libraries representing a broad range of growth conditions, stress responses, and developmental stages. These included libraries from P. infestans-potato and -tomato interactions, from which 963 pathogen ESTs were identified. To complement the ESTs, onefold coveragethe P. infestans genome was obtained and regions of coding potential identified. A unigene set of 18,256 sequences was derived from the EST and genomic data and characterized for potential functions, stage-specific patterns of expression, and codon bias. Cluster analysis of ESTs revealed major differences between the expressed gene content of mycelial and spore-related stages, and affinities between some growth conditions. Comparisons with databases of fungal pathogenicity genes revealed conserved elements of pa...

Search for production of vector-like quark pairs and of four top quarks in the lepton-plus-jets final state in pp collisions at √s = 8 TeV with the ATLAS detector

Abstract: A search for pair production of vector-like quarks, both up-type (T) and down-type (B), as well as for four-top-quark production, is presented. The search is based on pp collisions at TeV recorded in 2012 with the ATLAS detector at the CERN Large Hadron Collider and corresponding to an integrated luminosity of 20.3 fb(-1). Data are analysed in the lepton-plus-jets final state, characterised by an isolated electron or muon with high transverse momentum, large missing transverse momentum and multiple jets. Dedicated analyses are performed targeting three cases: a T quark with significant branching ratio to a W boson and a b-quark , and both a T quark and a B quark with significant branching ratio to a Higgs boson and a third-generation quark ( respectively). No significant excess of events above the Standard Model expectation is observed, and 95% CL lower limits are derived on the masses of the vector-like T and B quarks under several branching ratio hypotheses assuming contributions from T -> Wb, Zt, Ht and B -> Wt, Zb, Hb decays. The 95% CL observed lower limits on the T quark mass range between 715 GeV and 950 GeV for all possible values of the branching ratios into the three decay modes, and are the most stringent constraints to date. Additionally, the most restrictive upper bounds on four-top-quark production are set in a number of new physics scenarios.

Quaternary coral reef refugia preserved fish diversity

Abstract: The most prominent pattern in global marine biogeography is the biodiversity peak in the Indo-Australian Archipelago. Yet the processes that underpin this pattern are still actively debated. By reconstructing global marine paleoenvironments over the past 3 million years on the basis of sediment cores, we assessed the extent to which Quaternary climate fluctuations can explain global variation in current reef fish richness. Comparing global historical coral reef habitat availability with the present-day distribution of 6316 reef fish species, we find that distance from stable coral reef habitats during historical periods of habitat loss explains 62% of the variation in fish richness, outweighing present-day environmental factors. Our results highlight the importance of habitat persistence during periods of climate change for preserving marine biodiversity.

Modelling the future evolution of glaciers in the European Alps under the EURO-CORDEX RCM ensemble

Abstract: . Glaciers in the European Alps play an important role in the hydrological cycle, act as a source for hydroelectricity and have a large touristic importance. The future evolution of these glaciers is driven by surface mass balance and ice flow processes, of which the latter is to date not included explicitly in regional glacier projections for the Alps. Here, we model the future evolution of glaciers in the European Alps with GloGEMflow, an extended version of the Global Glacier Evolution Model (GloGEM), in which both surface mass balance and ice flow are explicitly accounted for. The mass balance model is calibrated with glacier-specific geodetic mass balances and forced with high-resolution regional climate model (RCM) simulations from the EURO-CORDEX ensemble. The evolution of the total glacier volume in the coming decades is relatively similar under the various representative concentrations pathways (RCP2.6, 4.5 and 8.5), with volume losses of about 47 %–52 % in 2050 with respect to 2017. We find that under RCP2.6, the ice loss in the second part of the 21st century is relatively limited and that about one-third (36.8 % ± 11.1 %, multi-model mean ±1σ ) of the present-day (2017) ice volume will still be present in 2100. Under a strong warming (RCP8.5) the future evolution of the glaciers is dictated by a substantial increase in surface melt, and glaciers are projected to largely disappear by 2100 ( 94.4±4.4 % volume loss vs. 2017). For a given RCP, differences in future changes are mainly determined by the driving global climate model (GCM), rather than by the RCM, and these differences are larger than those arising from various model parameters (e.g. flow parameters and cross-section parameterisation). We find that under a limited warming, the inclusion of ice dynamics reduces the projected mass loss and that this effect increases with the glacier elevation range, implying that the inclusion of ice dynamics is likely to be important for global glacier evolution projections.

Phase behavior and temperature-responsive molecular filters based on self-assembly of polystyrene-block-poly(N-isopropylacrylamide)-block-polystyrene

Abstract: This work describes the synthesis of temperature-responsive polystyrene-block-poly(N-isopropylacrylamide)-block-polystyrene triblock copolymers, i.e., PS-b-PNIPAM-b-PS, their self-assembly and phase behavior in bulk, and demonstration of aqueous thermoresponsive membranes. A series of PS-b-PNIPAM-b-PS triblock copolymers were synthesized using reversible addition−fragmentation chain transfer (RAFT) polymerization. The hydrophobic PS end blocks were selected to form the minority component, whereas the temperature-responsive PNIPAM midblock accounted for the majority component. The self-assembly and phase behavior in bulk of PS-b-PNIPAM-b-PS as well as selected blends with low molecular weight PNIPAM homopolymers were studied using transmission electron microscopy (TEM). Classical lamellar, cylindrical, spherical, and bicontinuous double gyroid morphologies were observed in the dried state. In aqueous solutions, the glassy PS domains act as physical cross-links, and hydrogels were therefore formed. The bulk...