Institution
University of Fribourg
Education•Fribourg, Freiburg, Switzerland•
About: University of Fribourg is a education organization based out in Fribourg, Freiburg, Switzerland. It is known for research contribution in the topics: Population & Glacier. The organization has 6040 authors who have published 14975 publications receiving 542500 citations. The organization is also known as: UNIFR & Universität Freiburg.
Topics: Population, Glacier, Excited state, Hubbard model, Scattering
Papers published on a yearly basis
Papers
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TL;DR: The ability to manipulate the band gap of Ta_{2}NiSe_{5} with light on the femtosecond time scale is demonstrated, and it is shown that below the critical excitation density of F_{C}=0.2 mJ cm^{-2, the band gap narrows transiently, while it is enhanced above F{C}.
Abstract: We report on the nonequilibrium dynamics of the electronic structure of the layered semiconductor ${\mathrm{Ta}}_{2}{\mathrm{NiSe}}_{5}$ investigated by time- and angle-resolved photoelectron spectroscopy. We show that below the critical excitation density of ${F}_{C}=0.2\text{ }\text{ }\mathrm{mJ}\text{ }{\mathrm{cm}}^{\ensuremath{-}2}$, the band gap narrows transiently, while it is enhanced above ${F}_{C}$. Hartree-Fock calculations reveal that this effect can be explained by the presence of the low-temperature excitonic insulator phase of ${\mathrm{Ta}}_{2}{\mathrm{NiSe}}_{5}$, whose order parameter is connected to the gap size. This work demonstrates the ability to manipulate the band gap of ${\mathrm{Ta}}_{2}{\mathrm{NiSe}}_{5}$ with light on the femtosecond time scale.
143 citations
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TL;DR: The draft genome was used to identify novel SSR markers, investigate target genes for abiotic stress resistance studies, and understand the evolution of the prolamin family of proteins that are responsible for the immune response to gluten.
Abstract: Tef (Eragrostis tef), an indigenous cereal critical to food security in the Horn of Africa, is rich in minerals and protein, resistant to many biotic and abiotic stresses and safe for diabetics as well as sufferers of immune reactions to wheat gluten. We present the genome of tef, the first species in the grass subfamily Chloridoideae and the first allotetraploid assembled de novo. We sequenced the tef genome for marker-assisted breeding, to shed light on the molecular mechanisms conferring tef’s desirable nutritional and agronomic properties, and to make its genome publicly available as a community resource. The draft genome contains 672 Mbp representing 87% of the genome size estimated from flow cytometry. We also sequenced two transcriptomes, one from a normalized RNA library and another from unnormalized RNASeq data. The normalized RNA library revealed around 38000 transcripts that were then annotated by the SwissProt group. The CoGe comparative genomics platform was used to compare the tef genome to other genomes, notably sorghum. Scaffolds comprising approximately half of the genome size were ordered by syntenic alignment to sorghum producing tef pseudo-chromosomes, which were sorted into A and B genomes as well as compared to the genetic map of tef. The draft genome was used to identify novel SSR markers, investigate target genes for abiotic stress resistance studies, and understand the evolution of the prolamin family of proteins that are responsible for the immune response to gluten. It is highly plausible that breeding targets previously identified in other cereal crops will also be valuable breeding targets in tef. The draft genome and transcriptome will be of great use for identifying these targets for genetic improvement of this orphan crop that is vital for feeding 50 million people in the Horn of Africa.
143 citations
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Northwood University1, Radboud University Nijmegen2, Ghent University Hospital3, New York University4, Cornell University5, National Institutes of Health6, University of Fribourg7, Paris Descartes University8, Lunenfeld-Tanenbaum Research Institute9, Johns Hopkins University School of Medicine10, Brigham and Women's Hospital11, University of Cincinnati Academic Health Center12, Yale University13
TL;DR: The PI-RADS Steering Committee discusses how the MRI pathway should be incorporated into routine clinical practice and the challenges in delivering the positive health impacts needed by men suspected of having clinically significant prostate cancer.
Abstract: High-quality evidence shows that MRI in biopsy-naive men can reduce the number of men who need prostate biopsy and can reduce the number of diagnoses of clinically insignificant cancers that are unlikely to cause harm. In men with prior negative biopsy results who remain under persistent suspicion, MRI improves the detection and localization of life-threatening prostate cancer with greater clinical utility than the current standard of care, systematic transrectal US-guided biopsy. Systematic analyses show that MRI-directed biopsy increases the effectiveness of the prostate cancer diagnosis pathway. The incorporation of MRI-directed pathways into clinical care guidelines in prostate cancer detection has begun. The widespread adoption of the Prostate Imaging Reporting and Data System (PI-RADS) for multiparametric MRI data acquisition, interpretation, and reporting has promoted these changes in practice. The PI-RADS MRI-directed biopsy pathway enables the delivery of key diagnostic benefits to men suspected of having cancer based on clinical suspicion. Herein, the PI-RADS Steering Committee discusses how the MRI pathway should be incorporated into routine clinical practice and the challenges in delivering the positive health impacts needed by men suspected of having clinically significant prostate cancer.
142 citations
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University of Gdańsk1, Delft University of Technology2, Harvard University3, University of Texas at Austin4, Technion – Israel Institute of Technology5, Wageningen University and Research Centre6, University of Illinois at Urbana–Champaign7, École Polytechnique Fédérale de Lausanne8, University of Rome Tor Vergata9, university of lille10, University of Luxembourg11, Brown University12, University of Victoria13, University of Grenoble14, Northwestern University15, Brigham Young University16, National Institute of Standards and Technology17, Technische Universität München18, University of the Basque Country19, Arizona State University20, University of Groningen21, University of Fribourg22, University of Toronto23, Northeastern University24
TL;DR: In this paper, the authors describe new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell profiling.
Abstract: Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at the single-cell level, single-cell profiling of proteomes is not yet established. Here we describe new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell profiling. These technologies will in turn facilitate biological discovery and open new avenues for ultrasensitive disease diagnostics. This Perspective describes new single-molecule protein sequencing and identification technologies alongside innovations in mass spectrometry that will eventually enable broad sequence coverage in single-cell proteomics.
142 citations
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30 Jun 2010TL;DR: In this article, the authors summarized and presented current understanding of rock glacier behaviour in the Swiss Alps and emphasises changes that have occurred over the last years and decades, indicating a common dependence on external climatic factors (summer air temperature, seasonal snow cover development) which govern changes observed in rock glacier creep rate.
Abstract: . The acceleration of rock glacier surface velocities over the two last decades and the destabilization of several landforms show that permafrost creep conditions are changing in the Alps. This article summarizes and presents current understanding of creep behaviour of rock glaciers in the Swiss Alps and emphasises changes that have occurred over the last years and decades. The almost homogeneous interannual behaviour of rock glaciers despite different geometry and activity rates indicates a common dependence on external climatic factors (summer air temperature, seasonal snowcover development) which govern changes observed in rock glacier creep rate. The article highlights ongoing efforts to document interannual variations of rock glacier kinematics for the whole area of the Swiss Alps.
142 citations
Authors
Showing all 6204 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jens Nielsen | 149 | 1752 | 104005 |
Sw. Banerjee | 146 | 1906 | 124364 |
Hans Peter Beck | 143 | 1134 | 91858 |
Patrice Nordmann | 127 | 790 | 67031 |
Abraham Z. Snyder | 125 | 329 | 91997 |
Csaba Szabó | 123 | 958 | 61791 |
Robert Edwards | 121 | 775 | 74552 |
Laurent Poirel | 117 | 621 | 53680 |
Thomas Münzel | 116 | 1055 | 57716 |
David G. Amaral | 112 | 302 | 49094 |
F. Blanc | 107 | 1514 | 58418 |
Markus Stoffel | 102 | 620 | 50796 |
Vincenzo Balzani | 101 | 476 | 45722 |
Enrico Bertini | 99 | 865 | 38167 |
Sandeep Kumar | 94 | 1563 | 38652 |