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Institution

University of Fribourg

EducationFribourg, Freiburg, Switzerland
About: University of Fribourg is a education organization based out in Fribourg, Freiburg, Switzerland. It is known for research contribution in the topics: Population & Glacier. The organization has 6040 authors who have published 14975 publications receiving 542500 citations. The organization is also known as: UNIFR & Universität Freiburg.


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Journal ArticleDOI
TL;DR: Findings from stress research in couples that has practical significance and may inspire clinical work are summarized and future directions in research and clincial significance are suggested.

470 citations

Journal ArticleDOI
Hajo Grundmann1, Hajo Grundmann2, Corinna Glasner1, Corinna Glasner3, Barbara Albiger4, David M. Aanensen5, David M. Aanensen3, Chris T Tomlinson5, Arjana Tambic Andrasevic, Rafael Cantón6, Yehuda Carmeli, Alexander W. Friedrich1, Christian G. Giske7, Christian G. Giske8, Youri Glupczynski9, Marek Gniadkowski, David M. Livermore10, David M. Livermore11, Patrice Nordmann12, Patrice Nordmann13, Laurent Poirel13, Laurent Poirel12, Gian Maria Rossolini14, Harald Seifert15, Alkiviadis Vatopoulos, Timothy R. Walsh16, Neil Woodford11, Dominique L Monnet4, Andi Koraqi, Denada Lacej, Petra Apfalter, Rainer Hartl, Te-Din Huang, T. Strateva, Y. Marteva-Proevska, Iva Butic, Despo Pieridou-Bagatzouni, Panagiota Maikanti-Charalampous, Jaroslav Hrabak, Helena Zemlickova, Anette M. Hammerum, Lotte Jakobsen, Marina Ivanova, Anastasia Pavelkovich, Jari Jalava, Monica Osterblad, Laurent Dortet, Sophie Vaux, Martin Kaase, Sören Gatermann, Kyriaki Tryfinopoulou, Akos Toth, Laura Janvari, Teck Wee Boo, Elaine McGrath, Amos Adler, Annalisa Pantosti, Monica Monaco, Lul Raka, Arsim Kurti, Arta Balode, Mara Saule, Jolanta Miciuleviciene, Aiste Mierauskaite, Monique Perrin-Weniger, Paul Reichert, Nina Nestorova, Sonia Debattista, Gordana Mijovic, Milena Lopicic, Ørjan Samuelsen, Bjørg Haldorsen, Dorota Zabicka, E Literacka, Manuela Caniça, Vera Manageiro, Ana Kaftandzieva, Elena Trajkovska-Dokic, Maria Damian, Brandusa Elena Lixandru, Zora Jelesic, Anika Trudic, Milan Niks, Eva Schreterova, Mateja Pirs, Tjasa Cerar, Jesús Oteo, Belén Aracil, Christian Giske8, Karin Sjostrom, D Gür, Asli Cakar, Katie L. Hopkins, Camilla Wiuff, Derek J. Brown 
TL;DR: The development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals are reported.
Abstract: Summary Background Gaps in the diagnostic capacity and heterogeneity of national surveillance and reporting standards in Europe make it difficult to contain carbapenemase-producing Enterobacteriaceae. We report the development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals. Methods National expert laboratories recruited hospitals with diagnostic capacities, who collected the first ten carbapenem non-susceptible clinical isolates of K pneumoniae or E coli and ten susceptible same-species comparator isolates and pertinent patient and hospital information. Isolates and data were relayed back to national expert laboratories, which made laboratory-substantiated information available for central analysis. Findings Between Nov 1, 2013, and April 30, 2014, 455 sentinel hospitals in 36 countries submitted 2703 clinical isolates (2301 [85%] K pneumoniae and 402 (15%) E coli ). 850 (37%) of 2301 K pneumoniae samples and 77 (19%) of 402 E coli samples were carbapenemase (KPC, NDM, OXA-48-like, or VIM) producers. The ratio of K pneumoniae to E coli was 11:1. 1·3 patients per 10 000 hospital admissions had positive clinical specimens. Prevalence differed greatly, with the highest rates in Mediterranean and Balkan countries. Carbapenemase-producing K pneumoniae isolates showed high resistance to last-line antibiotics. Interpretation This initiative shows an encouraging commitment by all participants, and suggests that challenges in the establishment of a continent-wide enhanced sentinel surveillance for carbapenemase-producing Enterobacteriaeceae can be overcome. Strengthening infection control efforts in hospitals is crucial for controlling spread through local and national health care networks. Funding European Centre for Disease Prevention and Control.

467 citations

Journal ArticleDOI
TL;DR: This review summarizes the current knowledge on eukaryotic ribosome assembly, with particular focus on the molecular role of the involved energy-consuming enzymes.

462 citations

Journal ArticleDOI
TL;DR: Concepts about host–parasite interactions are classified into these two families and discussed with the help of a defence component model and two-dimensional classification scheme of the individual components to clarify some of the confusing terminology.
Abstract: Evolutionary ecology has developed along two major conceptual avenues, starting from the observation that hosts vary in their immune defence against parasites The first avenue, rooted in life-history theory, assumes fitness costs of immune defence and tradeoffs in the face of limited resources, rather than specific host–parasite interactions. The second avenue focuses on specific responses, especially those generated by genotype–genotype interaction between and within host and parasite species. Specificity in the interactions between hosts and parasites play a crucial role in the field but analysis is difficult. Here, we classify concepts about host–parasite interactions into these two families and discuss their reconciliation with the help of a defence component model and two-dimensional classification scheme of the individual components. This helps to clarify some of the confusing terminology and might guide further research in the field.

461 citations

Journal ArticleDOI
TL;DR: In this article, the authors presented a method to detect the presence of a tumor in the human brain using the PhysRevB database, which was created on 2015-03-03, modified on 2017-05-12.
Abstract: Note: Times Cited: 251 Reference EPFL-ARTICLE-206012doi:10.1103/PhysRevB.74.045126View record in Web of Science URL: ://WOS:000239426800043 Record created on 2015-03-03, modified on 2017-05-12

454 citations


Authors

Showing all 6204 results

NameH-indexPapersCitations
Jens Nielsen1491752104005
Sw. Banerjee1461906124364
Hans Peter Beck143113491858
Patrice Nordmann12779067031
Abraham Z. Snyder12532991997
Csaba Szabó12395861791
Robert Edwards12177574552
Laurent Poirel11762153680
Thomas Münzel116105557716
David G. Amaral11230249094
F. Blanc107151458418
Markus Stoffel10262050796
Vincenzo Balzani10147645722
Enrico Bertini9986538167
Sandeep Kumar94156338652
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202367
2022348
20211,110
20201,112
2019966
2018924