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Institution

University of Geneva

EducationGeneva, Switzerland
About: University of Geneva is a education organization based out in Geneva, Switzerland. It is known for research contribution in the topics: Population & Planet. The organization has 26887 authors who have published 65265 publications receiving 2931373 citations. The organization is also known as: Geneva University & Universite de Geneve.
Topics: Population, Planet, Galaxy, Exoplanet, Stars


Papers
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Journal ArticleDOI
TL;DR: The remarkable shortening observed during isometric contraction suggests that, at rest, the gastrocnemius muscle and tendon are considerably slack, and the extrapolation of muscle architectural data obtained from cadaver conditions should be made only for matching muscle lengths.
Abstract: 1. Human gastrocnemius medialis architecture was analysed in vivo, by ultrasonography, as a function of joint angle at rest and during voluntary isometric contractions up to the maximum force (MCV). maximum force (MVC). 2. At rest, as ankle joint angle increased from 90 to 150 deg, pennation increased from 15.8 to 27.7 deg, fibre length decreased from 57.0 to 34.0 mm and the physiological cross-sectional area (PCSA) increased from 42.1 to 63.5 cm2. 3. From rest to MVC, at a fixed ankle joint angle of 110 deg, pennation angle increased from 15.5 to 33.6 deg and fibre length decreased from 50.8 to 32.9 mm, with no significant change in the distance between the aponeuroses. As a result of these changes the PCSA increased by 34.8%. 4. Measurements of pennation angle, fibre length and distance between the aponeuroses of the gastrocnemius medialis were also performed by ultrasound on a cadaver leg and found to be in good agreement with direct anatomical measurements. 5. It is concluded that human gastrocnemius medialis architecture is significantly affected both by changes of joint angle at rest and by isometric contraction intensity. The remarkable shortening observed during isometric contraction suggests that, at rest, the gastrocnemius muscle and tendon are considerably slack. The extrapolation of muscle architectural data obtained from cadavers to in vivo conditions should be made only for matching muscle lengths.

526 citations

Journal ArticleDOI
TL;DR: Bacterial contamination increased linearly with time on ungloved hands during patient care, and because hand antisepsis was superior to hand washing, intervention trials should explore the role of systematic handantisepsis as a cornerstone of infection control to reduce cross-transmission in hospitals.
Abstract: Background Cross-transmission of microorganisms by the hands of health care workers is considered the main route of spread of nosocomial infections. Objective To study the process of bacterial contamination of health care workers' hands during routine patient care in a large teaching hospital. Methods Structured observations of 417 episodes of care were conducted by trained external observers (S.T. and V.S.). Each observation period started after a hand-cleansing procedure and ended when the health care worker proceeded to clean his or her hands or at the end of a coherent episode of care. At the end of each period of observation, an imprint of the 5 fingertips of the dominant hand was taken and bacterial colony counts were quantified. Regression methods were used to model the intensity of bacterial contamination as a function of method of hand cleansing, use of gloves during patient care, duration and type of care, and hospital ward. Results Bacterial contamination increased linearly with time on ungloved hands during patient care (average, 16 colony-forming units [CFUs] per minute; 95% confidence interval, 11-21 CFUs per minute). Patient care activities independently (P Conclusions The duration and type of patient care affect hand contamination. Furthermore, because hand antisepsis was superior to hand washing, intervention trials should explore the role of systematic hand antisepsis as a cornerstone of infection control to reduce cross-transmission in hospitals.

526 citations

Journal ArticleDOI
TL;DR: This article showed that, despite projected reductions in tropical cyclone frequency, projected increases in demographic pressure and tropical cyclones intensity can be expected to exacerbate disaster risk, even with reported losses.
Abstract: Assessments of tropical cyclone risk trends are typically based on reported losses, which are biased by improvements in information access. Now research based on thousands of physically observed events and contextual factors shows that, despite projected reductions in tropical cyclone frequency, projected increases in demographic pressure and tropical cyclone intensity can be expected to exacerbate disaster risk.

526 citations

Journal ArticleDOI
A. Abada1, Marcello Abbrescia2, Marcello Abbrescia3, Shehu S. AbdusSalam4  +1491 moreInstitutions (239)
TL;DR: In this article, the authors present the second volume of the Future Circular Collider Conceptual Design Report, devoted to the electron-positron collider FCC-ee, and present the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan.
Abstract: In response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highest-luminosity high-energy lepton collider (FCC-ee) and an energy-frontier hadron collider (FCC-hh), which could, successively, be installed in the same 100 km tunnel. The scientific capabilities of the integrated FCC programme would serve the worldwide community throughout the 21st century. The FCC study also investigates an LHC energy upgrade, using FCC-hh technology. This document constitutes the second volume of the FCC Conceptual Design Report, devoted to the electron-positron collider FCC-ee. After summarizing the physics discovery opportunities, it presents the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan. FCC-ee can be built with today’s technology. Most of the FCC-ee infrastructure could be reused for FCC-hh. Combining concepts from past and present lepton colliders and adding a few novel elements, the FCC-ee design promises outstandingly high luminosity. This will make the FCC-ee a unique precision instrument to study the heaviest known particles (Z, W and H bosons and the top quark), offering great direct and indirect sensitivity to new physics.

526 citations

Journal ArticleDOI
TL;DR: It is found, analytically and numerically, that decorrelation does not imply an increase in information, and the effect of differential correlations on information can be detected with relatively simple decoders.
Abstract: Computational strategies used by the brain strongly depend on the amount of information that can be stored in population activity, which in turn strongly depends on the pattern of noise correlations. In vivo, noise correlations tend to be positive and proportional to the similarity in tuning properties. Such correlations are thought to limit information, which has led to the suggestion that decorrelation increases information. In contrast, we found, analytically and numerically, that decorrelation does not imply an increase in information. Instead, the only information-limiting correlations are what we refer to as differential correlations: correlations proportional to the product of the derivatives of the tuning curves. Unfortunately, differential correlations are likely to be very small and buried under correlations that do not limit information, making them particularly difficult to detect. We found, however, that the effect of differential correlations on information can be detected with relatively simple decoders.

525 citations


Authors

Showing all 27203 results

NameH-indexPapersCitations
JoAnn E. Manson2701819258509
Joseph L. Goldstein207556149527
Kari Stefansson206794174819
David Baltimore203876162955
Mark I. McCarthy2001028187898
Michael S. Brown185422123723
Yang Gao1682047146301
Napoleone Ferrara167494140647
Marc Weber1672716153502
Alessandro Melchiorri151674116384
Andrew D. Hamilton1511334105439
David P. Strachan143472105256
Andrew Beretvas1411985110059
Rainer Wallny1411661105387
Josh Moss139101989255
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023171
2022520
20214,280
20204,142
20193,580
20183,395