Institution
University of Geneva
Education•Geneva, Switzerland•
About: University of Geneva is a education organization based out in Geneva, Switzerland. It is known for research contribution in the topics: Population & Planet. The organization has 26887 authors who have published 65265 publications receiving 2931373 citations. The organization is also known as: Geneva University & Universite de Geneve.
Topics: Population, Planet, Galaxy, Exoplanet, Stars
Papers published on a yearly basis
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TL;DR: The large conformational flexibility of HSp90 and a multitude of dynamic co-chaperone complexes contribute to generating functional diversity, and allow Hsp90 to assist a wide range of substrates.
Abstract: Heat-shock protein 90 (Hsp90) is an abundant and highly conserved molecular chaperone that is essential for viability in eukaryotes. Hsp90 fulfills a housekeeping function in contributing to the folding, maintenance of structural integrity and proper regulation of a subset of cytosolic proteins. A remarkable proportion of its substrates are proteins involved in cell cycle control and signal transduction. Hsp90 acts with a cohort of Hsp90 co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. The large conformational flexibility of Hsp90 and a multitude of dynamic co-chaperone complexes contribute to generating functional diversity, and allow Hsp90 to assist a wide range of substrates.
754 citations
TL;DR: The difficulties the team faced in assigning functions by sequence similarity indicate that many of the automatic predictions by most of the software robots are probably erroneous.
751 citations
University of Saskatchewan1, Centre for Environment, Fisheries and Aquaculture Science2, Natural History Museum3, University of Rhode Island4, Sewanee: The University of the South5, Academy of Sciences of the Czech Republic6, National Institutes of Health7, Saint Petersburg State University8, University of Salzburg9, Centre national de la recherche scientifique10, Mississippi State University11, Science for Life Laboratory12, Uppsala University13, Charles University in Prague14, Spanish National Research Council15, Kaiserslautern University of Technology16, University of Duisburg-Essen17, University of Oslo18, Dalhousie University19, Pierre-and-Marie-Curie University20, American Museum of Natural History21, University of Michigan22, University of Warsaw23, University of São Paulo24, University of Paris25, University of British Columbia26, University of Guelph27, Royal Botanic Garden Edinburgh28, Kyungpook National University29, University of Geneva30, University of Alabama31, Pompeu Fabra University32, Edinburgh Napier University33, University of Arkansas34, Hosei University35, Oklahoma State University–Stillwater36, Chinese Academy of Sciences37
TL;DR: It is confirmed that eukaryotes form at least two domains, the loss of monophyly in the Excavata, robust support for the Haptista and Cryptista, and suggested primer sets for DNA sequences from environmental samples that are effective for each clade are provided.
Abstract: This revision of the classification of eukaryotes follows that of Adl et al., 2012 [J. Euk. Microbiol. 59(5)] and retains an emphasis on protists. Changes since have improved the resolution of many ...
750 citations
TL;DR: In this article, the transverse momentum balance in dijet and γ/Z+jets events is used to measure the jet energy response in the CMS detector, as well as the transversal momentum resolution.
Abstract: Measurements of the jet energy calibration and transverse momentum resolution in CMS are presented, performed with a data sample collected in proton-proton collisions at a centre-of-mass energy of 7TeV, corresponding to an integrated luminosity of 36pb−1. The transverse momentum balance in dijet and γ/Z+jets events is used to measure the jet energy response in the CMS detector, as well as the transverse momentum resolution. The results are presented for three different methods to reconstruct jets: a calorimeter-based approach, the ``Jet-Plus-Track'' approach, which improves the measurement of calorimeter jets by exploiting the associated tracks, and the ``Particle Flow'' approach, which attempts to reconstruct individually each particle in the event, prior to the jet clustering, based on information from all relevant subdetectors
750 citations
TL;DR: This paper proposed a componential model in which emotions are seen to develop from simpler, reflex-like forms (wired-in) sensory-motor processes to complex cognitive-emotional patterns that result from the participation of at least two distinct levels of memory and information processing, a schematic and a conceptual level.
Abstract: We first review the main points in the dispute about whether emotion is primary and independent of cognition (Zajonc), or secondary and always dependent upon cognition (Lazarus), and suggest that the dispute is largely one of definition. Because definitional disputes seldom clarify substantive, theoretical points, we suggest a variety of questions regarding cognition-emotion interaction. To stimulate discussion of these issues, we propose a componential model in which emotions are seen to develop from simpler, reflex-like forms (“wired-in” sensory-motor processes) to complex cognitive-emotional patterns that result from the participation of at least two distinct levels of memory and information processing, a schematic and a conceptual level. These systems are typically activated by a continuous stimulus check process which evaluates five environment-organism attributes: novelty; pleasantness; goal conductiveness; coping potential; and consistency with social norms and self-relevant values. Questi...
747 citations
Authors
Showing all 27203 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| JoAnn E. Manson | 270 | 1819 | 258509 |
| Joseph L. Goldstein | 207 | 556 | 149527 |
| Kari Stefansson | 206 | 794 | 174819 |
| David Baltimore | 203 | 876 | 162955 |
| Mark I. McCarthy | 200 | 1028 | 187898 |
| Michael S. Brown | 185 | 422 | 123723 |
| Yang Gao | 168 | 2047 | 146301 |
| Napoleone Ferrara | 167 | 494 | 140647 |
| Marc Weber | 167 | 2716 | 153502 |
| Alessandro Melchiorri | 151 | 674 | 116384 |
| Andrew D. Hamilton | 151 | 1334 | 105439 |
| David P. Strachan | 143 | 472 | 105256 |
| Andrew Beretvas | 141 | 1985 | 110059 |
| Rainer Wallny | 141 | 1661 | 105387 |
| Josh Moss | 139 | 1019 | 89255 |