Institution
University of Georgia
Education•Athens, Georgia, United States•
About: University of Georgia is a education organization based out in Athens, Georgia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 41934 authors who have published 93622 publications receiving 3713212 citations. The organization is also known as: UGA & Franklin College.
Topics: Population, Poison control, Gene, Genome, Virus
Papers published on a yearly basis
Papers
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TL;DR: A comprehensive school-based intervention can increase regular participation in vigorous physical activity among high-school girls and help to reduce the prevalence of obesity among this group.
Abstract: Objectives. Many adolescent girls fail to meet national guidelines for physical activity, and the prevalence of obesity is increasing among this group. Our study examined the effects of a comprehensive school-based intervention on physical activity among high-school girls.Methods. A group-randomized controlled field trial was conducted at 24 high schools. A school-based sample of 2744 girls (48.7% African American, 46.7% White) participated in a measurement protocol when they were in eighth and then ninth grade. A comprehensive physical activity intervention was designed to change the instructional program and the school environment to increase support for physical activity among girls.Results. At follow-up, 45% of girls in the intervention schools and 36% of girls in the control schools reported vigorous physical activity during an average of 1 or more 30-minute time blocks per day over a 3-day period.Conclusions. A comprehensive school-based intervention can increase regular participation in vigorous ph...
392 citations
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TL;DR: Stability of amyloid fibrils, rather than being driven exclusively by the formation of H-bonded beta-sheet, is achieved, as in globular proteins, through a balance of stabilizing and destabilizing forces.
392 citations
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TL;DR: In this paper, the efficacy of these sanitizers was evaluated, alone or through their sequential washing to achieve a 3 or more log reduction of mixed strains of E. coli O157:H7 on shredded lettuce and baby carrots.
Abstract: Chlorine dioxide (ClO2), ozone, and thyme essential oil has been found to be effective in reducing pathogens, including Escherichia coli O157:H7, on selected produce. The efficacy of these sanitizers was evaluated, alone or through their sequential washing to achieve a 3 or more log reduction of mixed strains of E. coli O157:H7 on shredded lettuce and baby carrots. Samples sprinkle inoculated with mixed strains of E. coli O157:H7 were air-dried for 1 h at 22±2°C in a biosafety cabinet, stored at 4°C for 24 h, and then treated with different concentrations of disinfectants and exposure time. Sterile deionized water washing resulted in approximately 1log reduction ofE. coli O157:H7 after 10 min washing of lettuce and baby carrots. Gaseous treatments resulted in higher log reductions in comparison to aqueous washing. However, decolorization of lettuce leaves was observed during long exposure time. A logarithmic reduction of 1.48–1.97log10 cfu/g was obtained using aqueous ClO2 (10.0 mg/L for 10 min) ozonated water (9.7 mg/L for 10 min) or thyme oil suspension (1.0 mL/L for 5 min) on lettuce and baby carrots. Of the three sequential washing treatments used in this study, thyme oil followed by aqueous ClO2/ozonated water, or ozonated water/aqueous ClO2 were significantly (P<0.05) more effective in reducing E. coli O157:H7 (3.75 and 3.99log, and 3.83 and 4.34 log reduction) on lettuce and baby carrots, respectively. The results obtained from this study indicate that sequential washing treatments could achieve 3–4log reduction of E. coli O157:H7 on shredded lettuce and baby carrots.
391 citations
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TL;DR: This review will examine the efficacy of cannabinoid CB2‐selective agonists in suppressing acute, inflammatory and neuropathic nociception following systemic and local routes of administration and the therapeutic potential and possible limitations of CB2-based pharmacotherapies for pathological pain states induced by tissue and nerve injury.
Abstract: Cannabinoids suppress behavioural responses to noxious stimulation and suppress nociceptive transmission through activation of CB1 and CB2 receptor subtypes. CB1 receptors are expressed at high levels in the central nervous system (CNS), whereas CB2 receptors are found predominantly, but not exclusively, outside the CNS. CB2 receptors are also upregulated in the CNS and dorsal root ganglia by pathological pain states. Here, we review behavioural, neurochemical and electrophysiological data, which identify cannabinoid CB2 receptors as a therapeutic target for treating pathological pain states with limited centrally, mediated side effects. The development of CB2-selective agonists (with minimal affinity for CB1) as well as mutant mice lacking CB2 receptors has provided pharmacological and genetic tools required to evaluate the effectiveness of CB2 agonists in suppressing persistent pain states. This review will examine the efficacy of cannabinoid CB2-selective agonists in suppressing acute, inflammatory and neuropathic nociception following systemic and local routes of administration. Data derived from behavioural, neurochemical and neurophysiological approaches are discussed to better understand the relationship between antinociceptive effects induced by CB2-selective agonists in behavioural studies and neural mechanisms of pain suppression. Finally, the therapeutic potential and possible limitations of CB2-based pharmacotherapies for pathological pain states induced by tissue and nerve injury are discussed.
391 citations
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University of Perpignan1, Pierre-and-Marie-Curie University2, Centre national de la recherche scientifique3, IFREMER4, University of Toulouse5, Université Paul Cézanne Aix-Marseille III6, University of Montpellier7, Stazione Zoologica Anton Dohrn8, Spanish National Research Council9, Institut de radioprotection et de sûreté nucléaire10, University of Nice Sophia Antipolis11, University College West12, École Normale Supérieure13, University of Georgia14, Plymouth Marine Laboratory15, university of lille16
TL;DR: In this article, a review of current functioning and responses of Mediterranean marine biogeochemical cycles and ecosystems with respect to key natural and anthropogenic drivers and to consider the ecosystems' responses to likely changes in physical, chemical and socio-economical forcings induced by global change and by growing anthropogenic pressure at the regional scale.
391 citations
Authors
Showing all 42268 results
Name | H-index | Papers | Citations |
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Rob Knight | 201 | 1061 | 253207 |
Feng Zhang | 172 | 1278 | 181865 |
Zhenan Bao | 169 | 865 | 106571 |
Carl W. Cotman | 165 | 809 | 105323 |
Yoshio Bando | 147 | 1234 | 80883 |
Mark Raymond Adams | 147 | 1187 | 135038 |
Han Zhang | 130 | 970 | 58863 |
Dmitri Golberg | 129 | 1024 | 61788 |
Godfrey D. Pearlson | 128 | 740 | 58845 |
Douglas E. Soltis | 127 | 612 | 67161 |
Richard A. Dixon | 126 | 603 | 71424 |
Ajit Varki | 124 | 542 | 58772 |
Keith A. Johnson | 120 | 798 | 51034 |
Gustavo E. Scuseria | 120 | 658 | 95195 |
Julian I. Schroeder | 120 | 315 | 50323 |