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Institution

University of Gothenburg

EducationGothenburg, Sweden
About: University of Gothenburg is a education organization based out in Gothenburg, Sweden. It is known for research contribution in the topics: Population & Poison control. The organization has 23855 authors who have published 65241 publications receiving 2606327 citations. The organization is also known as: Göteborg University & Gothenburg University.


Papers
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Journal ArticleDOI
TL;DR: Rather than one or two domestication events leading to the extant baker's yeasts, the population structure of S. cerevisiae shows a few well defined geographically isolated lineages and many different mosaics of these lineages, supporting the notion that human influence provided the opportunity for outbreeding and production of new combinations of pre-existing variation.
Abstract: The natural genetics of an organism is determined by the distribution of sequences of its genome. Here we present one- to four-fold, with some deeper, coverage of the genome sequences of over seventy isolates of the domesticated baker's yeast, Saccharomyces cerevisiae, and its closest relative, the wild S. paradoxus, which has never been associated with human activity. These were collected from numerous geographic locations and sources (including wild, clinical, baking, wine, laboratory and food spoilage). These sequences provide an unprecedented view of the population structure, natural (and artificial) selection and genome evolution in these species. Variation in gene content, SNPs, indels, copy numbers and transposable elements provide insights into the evolution of different lineages. Phenotypic variation broadly correlates with global genome-wide phylogenetic relationships however there is no correlation with source. S. paradoxus populations are well delineated along geographic boundaries while the variation among worldwide S. cerevisiae isolates show less differentiation and is comparable to a single S. paradoxus population. Rather than one or two domestication events leading to the extant baker's yeasts, the population structure of S. cerevisiae shows a few well defined geographically isolated lineages and many different mosaics of these lineages, supporting the notion that human influence provided the opportunity for outbreeding and production of new combinations of pre-existing variation.

377 citations

Journal ArticleDOI
TL;DR: In this paper, the authors survey recent evidence suggesting that market-oriented institutions and policies are strongly related to economic growth, focusing on studies using the economic freedom (EF) indicator of the Fraser Institute.
Abstract: This paper surveys recent evidence suggesting that market-oriented institutions and policies are strongly related to economic growth, focusing on studies using the economic freedom (EF) indicator of the Fraser Institute. This index is critically discussed. Also various serious shortcomings of empirical studies using this index are identified. Nevertheless, there are strong indications that liberalization, i.e. an increase in the EF index, stimulates economic growth. This paper also reviews studies on the determinants of EF. Political liberalization is often found to enhance economic liberalization, whereas there is less evidence for causality running in the other direction.

377 citations

Journal ArticleDOI
TL;DR: In this article, the authors identify some necessary conditions of learning to learn something, and demonstrate that what students learn in a sequence of lessons is a function of the pattern of variation and invariance constituted in that sequence.
Abstract: The purpose of this article is to identify some necessary conditions of learning To learn something, the learner must discern what is to be learned (the object of learning) Discerning the object of learning amounts to discerning its critical aspects To discern an aspect, the learner must experience potential alternatives, that is, variation in a dimension corresponding to that aspect, against the background of invariance in other aspects of the same object of learning (One could not discern the color of things, for instance, if there was only one color) The study results illustrate that what students learn in a sequence of lessons is indeed a function of the pattern of variation and invariance constituted in that sequence All teachers make use of variation and invariance in their teaching, but this study shows that teachers informed by a systematic framework do it more systematically, with striking effects on their students' learning

377 citations

Journal ArticleDOI
TL;DR: Compared with moderate sodium intake, high sodium intake is associated with an increased risk of cardiovascular events and death in hypertensive populations (no association in normotensive population), while the association of low sodium intake with increasedrisk of cardiovascular Events and death is observed in those with or without hypertension.

377 citations


Authors

Showing all 24120 results

NameH-indexPapersCitations
Peter J. Barnes1941530166618
Luigi Ferrucci1931601181199
Richard H. Friend1691182140032
Napoleone Ferrara167494140647
Timothy A. Springer167669122421
Anders Björklund16576984268
Hua Zhang1631503116769
Kaj Blennow1601845116237
Leif Groop158919136056
Tomas Hökfelt158103395979
Johan G. Eriksson1561257123325
Naveed Sattar1551326116368
Paul Elliott153773103839
Claude Bouchard1531076115307
Hakon Hakonarson152968101604
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023145
2022539
20215,065
20204,657
20194,254
20183,850