University of Gothenburg

About: University of Gothenburg is a education organization based out in Gothenburg, Sweden. It is known for research contribution in the topics: Population & Poison control. The organization has 23855 authors who have published 65241 publications receiving 2606327 citations. The organization is also known as: Göteborg University & Gothenburg University.

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

Abstract: Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding radiation damage. We applied serial femtosecond crystallography (SFX) using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals (less than 1 micrometer by 1 micrometer by 3 micrometers) of the well-characterized model protein lysozyme. The agreement with synchrotron data demonstrates the immediate relevance of SFX for analyzing the structure of the large group of difficult-to-crystallize molecules.

New attachment formation in the human periodontium by guided tissue regeneration. Case reports.

Abstract: The aim of the present study was to evaluate whether a regenerative surgical procedure, based on guided tissue regeneration, could predictably result in the formation of a new attachment in human teeth. The material included 12 teeth in 10 patients with advanced periodontal disease. Following flap elevation, scaling, root planing and removal of granulation tissue, a teflon membrane was placed over the denuded root surface in such a way that the epithelium and the gingival connective tissue were prevented from reaching contact with the root during healing. The flap was replaced on the outer surface of the membrane and secured with interdental sutures. This design of wound preparation gives preference to the cells originating from the periodontal ligament (PDL-cells) to repopulate the wound area adjacent to the root. Histologic analysis of the result of treatment was made in 5 of the 12 teeth scheduled for extraction. In the remaining 7 teeth, the result was evaluated using clinical measurements. The result of healing disclosed that in all teeth treated, substantial amounts of new attachment had formed. This suggests that predictable restitution of the attachment apparatus can be accomplished by using a method of treatment which is based on the principle of guided tissue regeneration.

Organization as rhetoric: Ambiguity in knowledge-intensive companies

Abstract: This article discusses the concepts of knowledge-intensive workers and firms. the functional view is questioned and a perspective on knowledge as institutionalized myth and rationality-surrogate is proposed. the ambiguity of knowledge work is emphasized and it is argued that a crucial dimension of a knowledge-intensive organization concerns the struggle with this ambiguity, which leads to efforts to refine various rhetorical strategies. Besides those stressing knowledge, science and rationality, the article points to rhetoric describing employees in knowledge-intensive firms as possessing other personal qualities and orientations than personnel employed in bureaucracies.

Measuring party positions in Europe: The Chapel Hill expert survey trend file, 1999-2010

Abstract: This article reports on the 2010 Chapel Hill expert surveys (CHES) and introduces the CHES trend file, which contains measures of national party positioning on European integration, ideology and several European Union (EU) and non-EU policies for 1999−2010. We examine the reliability of expert judgments and cross-validate the 2010 CHES data with data from the Comparative Manifesto Project and the 2009 European Elections Studies survey, and explore basic trends on party positioning since 1999. The dataset is available at the CHES website.