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Institution

University of Graz

EducationGraz, Steiermark, Austria
About: University of Graz is a education organization based out in Graz, Steiermark, Austria. It is known for research contribution in the topics: Population & Quantum chromodynamics. The organization has 17934 authors who have published 37489 publications receiving 1110980 citations. The organization is also known as: Carolo Franciscea Graecensis & Karl Franzens Universität.


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H. Thorsten Lumbsch1, Teuvo Ahti2, Susanne Altermann3, Guillermo Amo de Paz4, André Aptroot, Ulf Arup, Alejandrina Barcenas Peña5, Paulina A. Bawingan6, Michel Navarro Benatti, Luisa Betancourt, Curtis R. Björk7, Kansri Boonpragob8, Maarten Brand, Frank Bungartz9, Marcela Eugenia da Silva Cáceres, Mehtmet Candan10, José Luis Chaves, Philippe Clerc, Ralph S. Common, Brian J. Coppins11, Ana Crespo4, Manuela Dal-Forno12, Pradeep K. Divakar4, Melizar V. Duya13, John A. Elix14, Arve Elvebakk15, Johnathon D. Fankhauser16, Edith Farkas17, Lidia Itati Ferraro18, Eberhard Fischer19, David J. Galloway20, Ester Gaya21, Mireia Giralt, Trevor Goward22, Martin Grube23, Josef Hafellner23, Jesús E. Hernández M., Maria de los Angeles Herrera Campos5, Klaus Kalb, Ingvar Kärnefelt, Gintaras Kantvilas, Dorothee Killmann19, Paul M. Kirika, Kerry Knudsen24, Harald Komposch, Sergey Y. Kondratyuk, James D. Lawrey12, Armin Mangold, Marcelo Pinto Marcelli, Bruce McCune25, María Inés Messuti26, Andrea Michlig18, Ricardo Miranda González5, Bibiana Moncada, Alifereti Naikatini27, Matthew P. Nelsen28, Dag Olav Øvstedal29, Zdenek Palice30, Zdenek Palice31, Khwanruan Papong32, Sittiporn Parnmen8, Sergio Pérez-Ortega4, Christian Printzen, Víctor J. Rico4, Eimy Rivas Plata33, Javier Robayo, Dania Rosabal34, Ulrike Ruprecht35, Noris Salazar Allen36, Leopoldo G. Sancho4, Luciana Santo de Jesus, Tamires dos Santos Vieira, Matthias Schultz37, Mark R. D. Seaward38, Emmanuël Sérusiaux39, Imke Schmitt40, Harrie J. M. Sipman, Mohammad Sohrabi2, Ulrik Søchting41, Majbrit Zeuthen Søgaard41, Laurens B. Sparrius, Adriano Afonso Spielmann, Toby Spribille23, Jutarat Sutjaritturakan42, Achra Thammathaworn43, Arne Thell, Göran Thor44, Holger Thüs45, Einar Timdal46, Camille Truong, Roman Türk35, Loengrin Umana Tenorio, Dalip K. Upreti47, Pieter P. G. van den Boom, Mercedes Rebuelta4, Mats Wedin, Susan Will-Wolf48, Volkmar Wirth49, Nora Wirtz, Rebecca Yahr11, Kumelachew Yeshitela19, Frauke Ziemmeck9, Tim Wheeler, Robert Lücking1 
Field Museum of Natural History1, American Museum of Natural History2, University of California, Santa Cruz3, Complutense University of Madrid4, National Autonomous University of Mexico5, Saint Louis University6, University of Idaho7, Ramkhamhaeng University8, Charles Darwin Foundation9, Anadolu University10, Royal Botanic Garden Edinburgh11, George Mason University12, Conservation International13, Australian National University14, University of Tromsø15, University of Minnesota16, Hungarian Academy of Sciences17, National University of the Northeast18, University of Koblenz and Landau19, Landcare Research20, University of Barcelona21, University of British Columbia22, University of Graz23, University of California, Riverside24, Oregon University System25, National Scientific and Technical Research Council26, University of the South Pacific27, University of Chicago28, University of Bergen29, Academy of Sciences of the Czech Republic30, Charles University in Prague31, Mahasarakham University32, University of Illinois at Chicago33, Universidad de Oriente34, University of Salzburg35, Smithsonian Tropical Research Institute36, University of Hamburg37, University of Bradford38, University of Liège39, Goethe University Frankfurt40, University of Copenhagen41, King Mongkut's Institute of Technology Ladkrabang42, Khon Kaen University43, Swedish University of Agricultural Sciences44, Natural History Museum45, University of Oslo46, Council of Scientific and Industrial Research47, University of Wisconsin-Madison48, Museum für Naturkunde49
TL;DR: A total of 100 new species of lichenized fungi are described, representing a wide taxonomic and geographic range, and emphasizing the dire need for taxonomic expertise in lichenology.
Abstract: The number of undescribed species of lichenized fungi has been estimated at roughly 10,000. Describing and cataloging these would take the existing number of taxonomists several decades; however, the support for taxonomy is in decline worldwide. In this paper we emphasize the dire need for taxonomic expertise in lichenology. We bring together 103 colleagues from institutions worldwide to describe a total of 100 new species of lichenized fungi, representing a wide taxonomic and geographic range. The newly described species are: Acarospora flavisparsa, A. janae, Aderkomyces thailandicus, Amandinea maritima, Ampliotrema cocosense, Anomomorpha lecanorina, A. tuberculata, Aspicilia mansourii, Bacidina sorediata, Badimia multiseptata, B. vezdana, Biatora epirotica, Buellia sulphurica, Bunodophoron pinnatum, Byssoloma spinulosum, Calopadia cinereopruinosa, C. editae, Caloplaca brownlieae, C. decipioides, C. digitaurea, C. magnussoniana, C. mereschkowskiana, C. yorkensis, Calvitimela uniseptata, Chapsa microspora, C. psoromica, C. rubropulveracea, C. thallotrema, Chiodecton pustuliferum, Cladonia mongkolsukii, Clypeopyrenis porinoides, Coccocarpia delicatula, Coenogonium flammeum, Cresponea ancistrosporelloides, Crocynia microphyllina, Dictyonema hernandezii, D. hirsutum, Diorygma microsporum, D. sticticum, Echinoplaca pernambucensis, E. schizidiifera, Eremithallus marusae, Everniastrum constictovexans, Fellhanera borbonica, Fibrillithecis sprucei, Fissurina astroisidiata, F. nigrolabiata, F. subcomparimuralis, Graphis caribica, G. cerradensis, G. itatiaiensis, G. marusa, Gyalideopsis chicaque, Gyrotrema papillatum, Harpidium gavilaniae, Hypogymnia amplexa, Hypotrachyna guatemalensis, H. indica, H. lueckingii, H. paracitrella, H. paraphyscioides, H. parasinuosa, Icmadophila eucalypti, Krogia microphylla, Lecanora mugambii, L. printzenii, L. xanthoplumosella, Lecidea lygommella, Lecidella greenii, Lempholemma corticola, Lepraria sekikaica, Lobariella sipmanii, Megalospora austropacifica, M. galapagoensis, Menegazzia endocrocea, Myriotrema endoflavescens, Ocellularia albobullata, O. vizcayensis, Ochrolechia insularis, Opegrapha viridipruinosa, Pannaria phyllidiata, Parmelia asiatica, Pertusaria conspersa, Phlyctis psoromica, Placopsis imshaugii, Platismatia wheeleri, Porina huainamdungensis, Ramalina hyrcana, R. stoffersii, Relicina colombiana, Rhizocarpon diploschistidina, Sticta venosa, Sagenidiopsis isidiata, Tapellaria albomarginata, Thelotrema fijiense, Tricharia nigriuncinata, Usnea galapagona, U. pallidocarpa, Verrucaria rhizicola, and Xanthomendoza rosmarieae. In addition, three new combinations are proposed: Fibrillithecis dehiscens, Lobariella botryoides, and Lobariella pallida.

215 citations

Journal ArticleDOI
TL;DR: Current knowledge on the role and distribution of these specialised murein-degrading enzymes in diverse macromolecular transport systems is summarised and discussed.
Abstract: The cell wall of Gram-negative bacteria is essential for the integrity of the bacterial cell but also imposes a physical barrier to trans-envelope transport processes in which DNA and/or proteins are taken up or secreted by complex protein assemblies. The presence of genes encoding lytic transglycosylases in macromolecular transport systems (bacteriophage entry, type II secretion and type IV pilus synthesis, type III secretion, type IV secretion) suggests an important role for these specialised cell-wall-degrading enzymes. Such enzymes are capable of locally enlarging gaps in the peptidoglycan meshwork to allow the efficient assembly and anchoring of supramolecular transport complexes in the cell envelope. In this review, current knowledge on the role and distribution of these specialised murein-degrading enzymes in diverse macromolecular transport systems is summarised and discussed.

214 citations

Journal ArticleDOI
TL;DR: The data suggest that the presence of WMH exerts a subtle effect on neuropsychologic performance of normal elderly individuals, which becomes particularly evident on tasks measuring the speed of more complex mental processing.
Abstract: To determine the effects of MRI white matter hyperintensities (WMH) on cognitive functioning, we used neuropsychologic tests and MRI to study 150 elderly volunteers free of neuropsychiatric or general disease. There were 76 (50.3%) individuals without and 74 (49.7%) with WMH. The latter subset was older (61.3 +/- 6.6 years versus 58.5 +/- 5.8 years, p = 0.005), had a higher mean arterial blood pressure (103.7 +/- 11.4 mm Hg versus 99.9 +/- 10.3 mm Hg, p = 0.03), and a larger ventricular-to-intracranial-cavity ratio (6.3 +/- 5.6% versus 4.7 +/- 1.6%, p = 0.02). Individuals with WMH performed worse than their counterparts without such abnormalities on all tests administered. After adjusting for the group differences in age, arterial blood pressure, and ventricular size, we noted statistically significant results on form B of the Trail Making Test (121.8 +/- 37.8 msec versus 100.3 +/- 47.9 msec, p = 0.04), a complex reaction time task (680.8 +/- 104.9 msec versus 607.1 +/- 93.9 msec, p = 0.001), and the assembly procedure of the Purdue Peg-board Test (27.5 +/- 5.8 versus 30.6 +/- 5.9, p = 0.02). Partial correlations did not reveal any relationship between test scores and the semiautomatically assessed total area of WMH. Our data suggest that the presence of WMH exerts a subtle effect on neuropsychologic performance of normal elderly individuals, which becomes particularly evident on tasks measuring the speed of more complex mental processing.

214 citations

Journal ArticleDOI
TL;DR: AADvac1 had a favourable safety profile and excellent immunogenicity in this first-in-man study, and further trials are needed to corroborate the safety assessment and to establish proof of clinical efficacy of AADVac1.
Abstract: Summary Background Neurofibrillary pathology composed of tau protein is a main correlate of cognitive impairment in patients with Alzheimer's disease. Immunotherapy targeting pathological tau proteins is therefore a promising strategy for disease-modifying treatment of Alzheimer's disease. We have developed an active vaccine, AADvac1, against pathological tau proteins and assessed it in a phase 1 trial. Methods We did a first-in-man, phase 1, 12 week, randomised, double-blind, placebo-controlled study of AADvac1 with a 12 week open-label extension in patients aged 50–85 years with mild-to-moderate Alzheimer's disease at four centres in Austria. We randomly assigned patients with a computer-generated sequence in a 4:1 ratio overall to receive AADvac1 or placebo. They received three subcutaneous doses of AADvac1 or placebo from masked vaccine kits at monthly intervals, and then entered the open-label phase, in which all patients were allocated to AADvac1 treatment and received another three doses at monthly intervals. Patients, carers, and all involved with the trial were masked to treatment allocation. The primary endpoint was all-cause treatment-emergent adverse events, with separate analyses for injection site reactions and other adverse events. We include all patients who received at least one dose of AADvac1 in the safety assessment. Patients who had a positive IgG titre against the tau peptide component of AADvac1 at least once during the study were classified as responders. The first-in-man study is registered with EU Clinical Trials Register, number EudraCT 2012-003916-29, and ClinicalTrials.gov, number NCT01850238; the follow-up study, which is ongoing, is registered with EU Clinical Trials Register, number EudraCT 2013-004499-36, and ClinicalTrials.gov, number NCT02031198. Findings This study was done between June 9, 2013, and March 26, 2015. 30 patients were randomly assigned in the double-blind phase: 24 patients to the AADvac1 group and six to the placebo group. A total of 30 patients received AADvac1. Two patients withdrew because of serious adverse events. The most common adverse events were injection site reactions after administration (reported in 16 [53%] vaccinated patients [92 individual events]). No cases of meningoencephalitis or vasogenic oedema occurred after administration. One patient with pre-existing microhaemorrhages had newly occurring microhaemorrhages. Of 30 patients given AADvac1, 29 developed an IgG immune response. A geometric mean IgG antibody titre of 1:31415 was achieved. Baseline values of CD3+ CD4+ lymphocytes correlated with achieved antibody titres. Interpretation AADvac1 had a favourable safety profile and excellent immunogenicity in this first-in-man study. Further trials are needed to corroborate the safety assessment and to establish proof of clinical efficacy of AADvac1. Funding AXON Neuroscience SE.

214 citations

Journal ArticleDOI
TL;DR: In this paper, a theory suited for the quantum-mechanical description of surface plasmon polaritons (SPPs) is developed, and the coupling between these SPPs and a single molecule and the modified molecular dynamics in the presence of the nanoparticle is described within a combined Drude and boundary element approach.
Abstract: We theoretically investigate the strong coupling between a single molecule and a single metallic nanoparticle. A theory suited for the quantum-mechanical description of surface plasmon polaritons (SPPs) is developed. The coupling between these SPPs and a single molecule, and the modified molecular dynamics in the presence of the nanoparticle are described within a combined Drude and boundary-element-method approach. Our results show that strong coupling is possible for single molecules and metallic nanoparticles and can be observed in fluorescence spectroscopy through the splitting of emission peaks.

214 citations


Authors

Showing all 18136 results

NameH-indexPapersCitations
David Haussler172488224960
Russel J. Reiter1691646121010
Frederik Barkhof1541449104982
Philip Scheltens1401175107312
Christopher D.M. Fletcher13867482484
Jennifer S. Haas12884071315
Jelena Krstic12683973457
Michael A. Kamm12463753606
Frances H. Arnold11951049651
Gert Pfurtscheller11750762873
Georg Kresse111430244729
Manfred T. Reetz11095942941
Alois Fürstner10845943085
David N. Herndon108122754888
David J. Williams107206062440
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023174
2022422
20211,775
20201,759
20191,649
20181,541