Institution
University of Graz
Education•Graz, Steiermark, Austria•
About: University of Graz is a education organization based out in Graz, Steiermark, Austria. It is known for research contribution in the topics: Population & Quantum chromodynamics. The organization has 17934 authors who have published 37489 publications receiving 1110980 citations. The organization is also known as: Carolo Franciscea Graecensis & Karl Franzens Universität.
Papers published on a yearly basis
Papers
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TL;DR: The pulsatile flow field in an anatomically realistic model of the bifurcation of the left anterior descending coronary artery and its first diagonal branch was simulated numerically and measured by laser Doppler anemometry.
202 citations
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TL;DR: The objective of the current study was to compare the discriminating accuracy of four prognostic models developed to predict the survival of patients undergoing nephrectomy for nonmetastatic renal cell carcinoma (RCC).
Abstract: BACKGROUND
The objective of the current study was to compare, in a large multicenter study, the discriminating accuracy of four prognostic models developed to predict the survival of patients undergoing nephrectomy for nonmetastatic renal cell carcinoma (RCC).
METHODS
A total of 2404 records of patients from 6 European centers were retrospectively reviewed. For each patient, prognostic scores were calculated according to four models: the Kattan model, the University of California at Los Angeles integrated staging system (UISS) model, the Yaycioglu model, and the Cindolo model. Survival curves were estimated by the Kaplan–Meier method and compared by the log-rank test. Discriminating ability was assessed by the Harrell c-index for censored data. The primary end point was overall survival (OS), and the secondary end points were cancer-specific survival (CSS) and disease recurrence-free survival (RFS).
RESULTS
At last follow-up, 541 subjects had died of any causes, with a 5-year OS rate of 80%. The 5-year CSS and RFS rates were 85% and 78%, respectively. All models discriminated well (P < 0.0001). The c-indexes for OS were 0.706 for the Kattan nomogram, 0.683 for the UISS model, and 0.589 and 0.615 for the Yaycioglu and Cindolo models, respectively. The Kattan nomogram was found to improve discrimination substantially in the UISS intermediate-risk patients.
CONCLUSIONS
The current study appears to better define the general applicability of prognostic models for predicting survival in patients with nonmetastatic RCC treated with nephrectomy. The results suggest that postoperative models discriminate substantially better than preoperative ones. The Kattan model was consistently found to be the most accurate, although the UISS model was only slightly less well performing. The Kattan model can be useful in the UISS intermediate-risk patients. Cancer 2005. © 2005 American Cancer Society.
201 citations
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TL;DR: Creative problem solving was generally accompanied by lower levels of cortical arousal and more original responses were associated with a stronger task-related alpha synchronization in posterior cortices, which was moderated by verbal IQ and sex.
201 citations
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201 citations
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TL;DR: It is concluded that despite the abundance of topical and systemic treatment options, disease management in patients with severe chronic HE is frequently inadequate and there is a strong need for RCTs of existing and new treatment options based on clearly diagnosed subtypes of HE and its severity.
Abstract: Hand eczema (HE) is one of the most frequent skin diseases and has often a chronically relapsing course with a poor prognosis resulting in a high social and economic impact for the individual and the society. In this article, we highlight the results of an expert workshop on the 'management of severe chronic hand eczema' with the focus on the epidemiology, the burden of severe HE, its classification and diagnostic procedures, and the current status of treatment options according to an evidence-based approach (randomized controlled clinical trials, RCTs). We conclude that despite the abundance of topical and systemic treatment options, disease management in patients with severe chronic HE is frequently inadequate. There is a strong need for RCTs of existing and new treatment options based on clearly diagnosed subtypes of HE and its severity.
201 citations
Authors
Showing all 18136 results
Name | H-index | Papers | Citations |
---|---|---|---|
David Haussler | 172 | 488 | 224960 |
Russel J. Reiter | 169 | 1646 | 121010 |
Frederik Barkhof | 154 | 1449 | 104982 |
Philip Scheltens | 140 | 1175 | 107312 |
Christopher D.M. Fletcher | 138 | 674 | 82484 |
Jennifer S. Haas | 128 | 840 | 71315 |
Jelena Krstic | 126 | 839 | 73457 |
Michael A. Kamm | 124 | 637 | 53606 |
Frances H. Arnold | 119 | 510 | 49651 |
Gert Pfurtscheller | 117 | 507 | 62873 |
Georg Kresse | 111 | 430 | 244729 |
Manfred T. Reetz | 110 | 959 | 42941 |
Alois Fürstner | 108 | 459 | 43085 |
David N. Herndon | 108 | 1227 | 54888 |
David J. Williams | 107 | 2060 | 62440 |