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Institution

University of Graz

EducationGraz, Steiermark, Austria
About: University of Graz is a education organization based out in Graz, Steiermark, Austria. It is known for research contribution in the topics: Population & Quantum chromodynamics. The organization has 17934 authors who have published 37489 publications receiving 1110980 citations. The organization is also known as: Carolo Franciscea Graecensis & Karl Franzens Universität.


Papers
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Journal ArticleDOI
Martin Koller1
TL;DR: Traditional processing techniques for production of PHA-based medical devices, such as melt-spinning, melt extrusion, or solvent evaporation, and emerging processing techniques like 3D-printing, computer-aided wet-sp spinning, laser perforation, and electrospinning are described.
Abstract: Polyhydroxyalkanoates (PHA) are bio-based microbial biopolyesters; their stiffness, elasticity, crystallinity and degradability are tunable by the monomeric composition, selection of microbial production strain, substrates, process parameters during production, and post-synthetic processing; they display biological alternatives for diverse technomers of petrochemical origin. This, together with the fact that their monomeric and oligomeric in vivo degradation products do not exert any toxic or elsewhere negative effect to living cells or tissue of humans or animals, makes them highly stimulating for various applications in the medical field. This article provides an overview of PHA application in the therapeutic, surgical and tissue engineering area, and reviews strategies to produce PHA at purity levels high enough to be used in vivo. Tested applications of differently composed PHA and advanced follow-up products as carrier materials for controlled in vivo release of anti-cancer drugs or antibiotics, as scaffolds for tissue engineering, as guidance conduits for nerve repair or as enhanced sutures, implants or meshes are discussed from both a biotechnological and a material-scientific perspective. The article also describes the use of traditional processing techniques for production of PHA-based medical devices, such as melt-spinning, melt extrusion, or solvent evaporation, and emerging processing techniques like 3D-printing, computer-aided wet-spinning, laser perforation, and electrospinning.

196 citations

Journal ArticleDOI
TL;DR: There are now a total of nine patients diagnosed with ICOS deficiency most likely due to a common founder, and ICOS-L deficiency could not be identified in families with AR-CVID.

196 citations

Journal ArticleDOI
TL;DR: A perspective is provided by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions about the relationship between liver disease and insulin resistance.

195 citations

Journal ArticleDOI
Fritz Paltauf1
TL;DR: A possible function of plasmalogens as antioxidants has been demonstrated with cultured cells and might play a role in serum lipoproteins.

195 citations

Journal ArticleDOI
TL;DR: In this paper, the authors estimate the position of the pressure balance boundary between Coronal Mass Ejection (CME) and stellar wind ram pressures and the planetary ionosphere pressure for non- or weakly magnetized gas giants at close orbits.
Abstract: Aims. We study the possible atmospheric mass loss from 57 known transiting exoplanets around F, G, K, and M-type stars over evolutionary timescales. For stellar wind induced mass loss studies, we estimate the position of the pressure balance boundary between Coronal Mass Ejection (CME) and stellar wind ram pressures and the planetary ionosphere pressure for non- or weakly magnetized gas giants at close orbits. Methods. The thermal mass loss of atomic hydrogen is calculated by a mass loss equation where we consider a realistic heating efficiency, a radius-scaling law and a mass loss enhancement factor due to stellar tidal forces. The model takes into account the temporal evolution of the stellar EUV flux by applying power laws for F, G, K, and M-type stars. The planetary ionopause obstacle, which is an important factor for ion pick-up escape from non- or weakly magnetized gas giants is estimated by applying empirical power-laws. Results. By assuming a realistic heating efficiency of about 10–25% we found that WASP-12b may have lost about 6–12% of its mass during its lifetime. A few transiting low density gas giants at similar orbital location, like WASP-13b, WASP-15b, CoRoT-1b or CoRoT-5b may have lost up to 1–4% of their initial mass. All other transiting exoplanets in our sample experience negligible thermal loss (≤1%) during their lifetime. We found that the ionospheric pressure can balance the impinging dense stellar wind and average CME plasma flows at distances which are above the visual radius of “Hot Jupiters”, resulting in mass losses <2% over evolutionary timescales. The ram pressure of fast CMEs cannot be balanced by the ionospheric plasma pressure for orbital distances between 0.02–0.1 AU. Therefore, collisions of fast CMEs with hot gas giants should result in large atmospheric losses which may influence the mass evolution of gas giants with masses

195 citations


Authors

Showing all 18136 results

NameH-indexPapersCitations
David Haussler172488224960
Russel J. Reiter1691646121010
Frederik Barkhof1541449104982
Philip Scheltens1401175107312
Christopher D.M. Fletcher13867482484
Jennifer S. Haas12884071315
Jelena Krstic12683973457
Michael A. Kamm12463753606
Frances H. Arnold11951049651
Gert Pfurtscheller11750762873
Georg Kresse111430244729
Manfred T. Reetz11095942941
Alois Fürstner10845943085
David N. Herndon108122754888
David J. Williams107206062440
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023174
2022422
20211,775
20201,759
20191,649
20181,541