University of Grenoble

About: University of Grenoble is a education organization based out in Saint-Martin-d'Hères, France. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 25658 authors who have published 45143 publications receiving 909760 citations.

Development of an updated global land In situ‐based data set of temperature and precipitation extremes : HadEX3

Abstract: Robert Dunn was supported by the Met Office Hadley Centre Climate Programme funded by BEIS and Defra (GA01101) and thanks Nick Rayner and Lizzie Good for helpful comments on the manuscript Lisa Alexander is supported by the Australian Research Council (ARC) Grants DP160103439 and CE170100023 Markus Donat acknowledges funding by the Spanish Ministry for the Economy, Industry and Competitiveness Ramon y Cajal 2017 Grant Reference RYC‐2017‐22964 Mohd Noor'Arifin Bin Hj Yussof and Muhammad Khairul Izzat Bin Ibrahim thank the Brunei Darussalam Meteorological Department (BDMD) Ying Sun was supported by China funding agencies 2018YFA0605604 and 2018YFC1507702 Fatemeh Rahimzadeh and Mahbobeh Khoshkam thank IR of Iranian Meteorological Organization (IRIMO) and the Atmospheric Science and Meteorological Organization Research Center (ASMERC) for Data and also sharing their experiences, especially Abbas Rangbar Jose Marengo was supported by the National Institute of Science and Technology for Climate Change Phase 2 under CNPq Grant 465501/2014‐1, FAPESP Grants 2014/50848‐9 and 2015/03804‐9, and the National Coordination for High Level Education and Training (CAPES) Grant 88887136402‐00INCT The team that worked on the data in West Africa received funding from the UK's National Environment Research Council (NERC)/Department for International Development DFID) Future Climate For Africa programme, under the AMMA‐2050 project (Grants NE/M020428/1 and NE/M019969/1) Data from Southeast Asia (excl Indonesia) was supported by work on using ClimPACT2 during the Second Workshop on ASEAN Regional Climate Data, Analysis and Projections (ARCDAP‐2), 25–29 March 2019, Singapore, jointly funded by Meteorological Service Singapore and WMO through the Canada‐Climate Risk and Early Warning Systems (CREWS) initiative This research was supported by Thai Meteorological Department (TMD) and Thailand Science Research and Innovation (TSRI) under Grant RDG6030003 Daily data for Mexico were provided by the Servicio Meteorologico Nacional (SMN) of Comision Nacional del Agua (CONAGUA) We acknowledge the data providers in the ECA&D project (https://wwwecadeu), the SACA&D project (https://saca-bmkgknminl), and the LACA&D project (https://ciifenknminl) We thank the three anonymous reviewers for their detailed comments which improved the manuscript

Twenty-first century glacier slowdown driven by mass loss in High Mountain Asia

Abstract: Glaciers in High Mountain Asia have experienced heterogeneous rates of loss since the 1970s. Yet, the associated changes in ice flow that lead to mass redistribution and modify the glacier sensitivity to climate are poorly constrained. Here we present observations of changes in ice flow for all glaciers in High Mountain Asia over the period 2000–2017, based on one million pairs of optical satellite images. Trend analysis reveals that in 9 of the 11 surveyed regions, glaciers show sustained slowdown concomitant with ice thinning. In contrast, the stable or thickening glaciers of the Karakoram and West Kunlun regions experience slightly accelerated glacier flow. Up to 94% of the variability in velocity change between regions can be explained by changes in gravitational driving stress, which in turn is largely controlled by changes in ice thickness. We conclude that, despite the complexities of individual glacier behaviour, decadal and regional changes in ice flow are largely insensitive to changes in conditions at the bed of the glacier and can be well estimated from ice thickness change and slope alone. Changes in glacier speed in High Mountain Asia are closely linked to mass balance through gravitational driving stress, and largely insensitive to basal conditions, according to satellite-derived ice-flow observations.

The nature of domain walls in ultrathin ferromagnets revealed by scanning nanomagnetometry

Abstract: The capacity to propagate magnetic domain walls with spin-polarized currents underpins several schemes for information storage and processing using spintronic devices. A key question involves the internal structure of the domain walls, which governs their response to certain current-driven torques such as the spin Hall effect. Here we show that magnetic microscopy based on a single nitrogen-vacancy defect in diamond can provide a direct determination of the internal wall structure in ultrathin ferromagnetic films under ambient conditions. We find pure Bloch walls in Ta/CoFeB(1 nm)/MgO, while left-handed Neel walls are observed in Pt/Co(0.6 nm)/AlOx. The latter indicates the presence of a sizable interfacial Dzyaloshinskii-Moriya interaction, which has strong bearing on the feasibility of exploiting novel chiral states such as skyrmions for information technologies.

Frequency fluctuations in silicon nanoresonators

Abstract: Frequency stability is key to the performance of nanoresonators. This stability is thought to reach a limit with the resonator's ability to resolve thermally induced vibrations. Although measurements and predictions of resonator stability usually disregard fluctuations in the mechanical frequency response, these fluctuations have recently attracted considerable theoretical interest. However, their existence is very difficult to demonstrate experimentally. Here, through a literature review, we show that all studies of frequency stability report values several orders of magnitude larger than the limit imposed by thermomechanical noise. We studied a monocrystalline silicon nanoresonator at room temperature and found a similar discrepancy. We propose a new method to show that this was due to the presence of frequency fluctuations, of unexpected level. The fluctuations were not due to the instrumentation system, or to any other of the known sources investigated. These results challenge our current understanding of frequency fluctuations and call for a change in practices.

HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism.

Abstract: Plasmacytoid DCs (pDCs) have been implicated as crucial cells in antiviral immune responses On recognizing HIV, they become activated, secreting large amounts of IFN-α and inflammatory cytokines, thereby potentiating innate and adaptive antiviral immune responses Here, we have shown that HIV-stimulated human pDCs can also induce the differentiation of naive CD4+ T cells into Tregs with suppressive function This differentiation was independent of pDC production of IFN-α and primarily dependent on pDC expression of indoleamine 2,3-dioxygenase, which was induced through the TLR/MyD88 pathway, following binding of HIV to CD4 and triggering of TLR7 by HIV genomic RNA Functionally, the Tregs induced by pDCs were shown to inhibit the maturation of bystander conventional DCs This study therefore reveals what we believe to be a novel mechanism by which pDC may regulate and potentially limit anti-HIV immune responses