Institution
University of Grenoble
Education•Saint-Martin-d'Hères, France•
About: University of Grenoble is a education organization based out in Saint-Martin-d'Hères, France. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 25658 authors who have published 45143 publications receiving 909760 citations.
Topics: Population, Large Hadron Collider, Planet, Nanowire, Stars
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University of Michigan1, University of Alabama at Birmingham2, University of Washington3, Indiana University4, University of Hawaii5, Lahey Hospital & Medical Center6, University of Houston7, Central Michigan University8, University of Grenoble9, Erasmus University Rotterdam10, Stony Brook University11, University of North Carolina at Chapel Hill12, Uniformed Services University of the Health Sciences13, Duke University14, Paris Descartes University15, Medical University of Silesia16, University of Otago17, Mayo Clinic18, University of California, Los Angeles19, Oregon Health & Science University20, Rutgers University21
TL;DR: The CEAP Task Force has adopted the revised Delphi process and made several changes, including adding Corona phlebectatica as the C4c clinical subclass, introducing the modifier "r" for recurrent varicose veins and recurrent venous ulcers, and replacing numeric descriptions of the venous segments by their common abbreviations.
Abstract: The CEAP (Clinical-Etiology-Anatomy-Pathophysiology) classification is an internationally accepted standard for describing patients with chronic venous disorders and it has been used for reporting clinical research findings in scientific journals. Developed in 1993, updated in 1996, and revised in 2004, CEAP is a classification system based on clinical manifestations of chronic venous disorders, on current understanding of the etiology, the involved anatomy, and the underlying venous pathology. As the evidence related to these aspects of venous disorders, and specifically of chronic venous diseases (CVD, C2-C6) continue to develop, the CEAP classification needs periodic analysis and revisions. In May of 2017, the American Venous Forum created a CEAP Task Force and charged it to critically analyze the current classification system and recommend revisions, where needed. Guided by four basic principles (preservation of the reproducibility of CEAP, compatibility with prior versions, evidence-based, and practical for clinical use), the Task Force has adopted the revised Delphi process and made several changes. These changes include adding Corona phlebectatica as the C4c clinical subclass, introducing the modifier "r" for recurrent varicose veins and recurrent venous ulcers, and replacing numeric descriptions of the venous segments by their common abbreviations. This report describes all these revisions and the rationale for making these changes.
288 citations
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TL;DR: In this paper, a 3D model of the Rhone River in France is considered in 3 dimensions: the upstream-downstream progression, the transversal dimension (main stream, side-arms, marshes, flood plain and their interconnections), and the vertical dimension (relationships between epigean and ground waters).
Abstract: The hydrosystem of the Rhǒne River, France, is considered in 3 dimensions: the upstream-downstream progression, the transversal dimension (main stream, side-arms, marshes, flood plain and their interconnections), and the vertical dimension (relationships between epigean and ground waters). Emphasis is placed on the temporal dimension, which considers changes in the river's dynamics, and on the development of its ecosystems over several centuries.
Analyses were performed on different spatial scales; the definitions of functional sectors, functional sets and functional units are based on a combination of geomorphic patterns, fluvial dynamics and ecological processes. Synchronic and diachronic analyses were carried out using functional describers (granulometry and organic content of sediments, floral and faunal communities).
These studies deal mainly with the distrubed hydrosystems of regulated rivers. The changes of the ecological successions are focused on after reference to natural models and the reconstitution of ancient human disturbances. Predictive scenarios are proposed to promote ecological management of the alluvial plains in the event of hydroelectric development.
288 citations
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TL;DR: A review from sociological concepts to social robotics and human-aware navigation, and recent robotic experiments focusing on the way social conventions and robotics must be linked are presented.
Abstract: In the context of a growing interest in modelling human behavior to increase the robots' social abilities, this article presents a survey related to socially-aware robot navigation. It presents a review from sociological concepts to social robotics and human-aware navigation. Social cues, signals and proxemics are discussed. Socially aware behavior in terms of navigation is tackled also. Finally, recent robotic experiments focusing on the way social conventions and robotics must be linked is presented.
287 citations
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TL;DR: The concept that dysfunction of motor, limbic and associative cortico-basal ganglia-thalamocortical loops underlies these various disorders, which might now be amenable to DBS treatment, is discussed.
287 citations
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TL;DR: In this paper, the anti-inflammatory role of the VN has been investigated in the treatment of TNFα-related diseases such as inflammatory bowel disease and rheumatoid arthritis.
Abstract: Brain and viscera interplay within the autonomic nervous system where the vagus nerve (VN), containing approximately 80% afferent and 20% efferent fibres, plays multiple key roles in the homeostatic regulations of visceral functions. Recent data have suggested the anti-inflammatory role of the VN. This vagal function is mediated through several pathways, some of them still debated. The first one is the anti-inflammatory hypothalamic-pituitary-adrenal axis which is stimulated by vagal afferent fibres and leads to the release of cortisol by the adrenal glands. The second one, called the cholinergic anti-inflammatory pathway, is mediated through vagal efferent fibres that synapse onto enteric neurons which release acetylcholine (ACh) at the synaptic junction with macrophages. ACh binds to α-7-nicotinic ACh receptors of those macrophages to inhibit the release of tumour necrosis (TNF)α, a pro-inflammatory cytokine. The last pathway is the splenic sympathetic anti-inflammatory pathway, where the VN stimulates the splenic sympathetic nerve. Norepinephrine (noradrenaline) released at the distal end of the splenic nerve links to the β2 adrenergic receptor of splenic lymphocytes that release ACh. Finally, ACh inhibits the release of TNFα by spleen macrophages through α-7-nicotinic ACh receptors. Understanding of these pathways is interesting from a therapeutic point of view, since they could be targeted in various ways to stimulate anti-inflammatory regulation in TNFα-related diseases such as inflammatory bowel disease and rheumatoid arthritis. Among others, VN stimulation, either as an invasive or non-invasive procedure, is becoming increasingly frequent and several clinical trials are ongoing to evaluate the potential effectiveness of this therapy to alleviate chronic inflammation.
287 citations
Authors
Showing all 25961 results
Name | H-index | Papers | Citations |
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Dieter Lutz | 139 | 671 | 67414 |
Marcella Bona | 137 | 1391 | 92162 |
Nicolas Berger | 137 | 1581 | 96529 |
Cordelia Schmid | 135 | 464 | 103925 |
J. F. Macías-Pérez | 134 | 486 | 94715 |
Marina Cobal | 132 | 1078 | 85437 |
Lydia Roos | 132 | 1284 | 89435 |
Tetiana Hryn'ova | 131 | 1059 | 84260 |
Johann Collot | 131 | 1018 | 82865 |
Remi Lafaye | 131 | 1012 | 83281 |
Jan Stark | 131 | 1186 | 87025 |
Sabine Crépé-Renaudin | 129 | 1142 | 82741 |
Isabelle Wingerter-Seez | 129 | 930 | 79689 |
James Alexander | 129 | 886 | 75096 |
Jessica Levêque | 129 | 1006 | 70208 |